Browsing Faculty of Medicine by Author "Bjørndal, Bodil"
Now showing items 21-34 of 34
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Plasma Cholesterol- and Body Fat-Lowering Effects of Chicken Protein Hydrolysate and Oil in High-Fat Fed Male Wistar Rats
Aloysius, Thomas Aquinas; Tillander, Veronika; Pedrelli, Matteo; Dankel, Simon Erling Nitter; Berge, Rolf Kristian; Bjørndal, Bodil (Journal article; Peer reviewed, 2022)Rest raw materials provide a new source of bioactive dietary ingredients, and this study aimed to determine the health effects of diets with chicken protein hydrolysate (CPH) and chicken oil (CO) generated from deboned ... -
The PPAR pan-agonist tetradecylthioacetic acid promotes redistribution of plasma cholesterol towards large HDL
Lundåsen, Thomas; Pedrelli, Matteo; Bjørndal, Bodil; Rozell, Björn; Kuiper, Raoul; Burri, Lena; Pavanello, Chiara; Turri, Marta; Skorve, Jon; Berge, Rolf Kristian; Alexson, Stefan E.H.; Tillander, Veronika (Journal article; Peer reviewed, 2020)Tetradecylthioacetic acid (TTA) is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including ... -
A protein extract from chicken reduces plasma homocysteine in rats
Lysne, Vegard; Bjørndal, Bodil; Vik, Rita; Nordrehaug, Jan Erik; Skorve, Jon; Nygård, Ottar; Berge, Rolf Kristian (Peer reviewed; Journal article, 2015-06-04)The present study aimed to evaluate effects of a water-soluble protein fraction of chicken (CP), with a low methionine/glycine ratio, on plasma homocysteine and metabolites related to homocysteine metabolism. Male Wistar ... -
A randomized, double-blind, placebo-controlled clinical study to investigate the efficacy of herring roe oil for treatment of psoriasis
Tveit, Kåre Steinar; Brokstad, Karl Albert; Berge, Rolf Kristian; Sæbø, Per Christian; Hallaråker, Hogne; Brekke, Stian; Meland, Nils; Bjørndal, Bodil (Journal article; Peer reviewed, 2020-05-07)The effect of omega-3 polyunsaturated fatty acid supplements in patients with psoriasis vulgaris has previously been investigated, but interventions varied in source, composition, dose, administration route and duration ... -
A salmon peptide diet alleviates experimental colitis as compared with fish oil
Grimstad, Tore; Bjørndal, Bodil; Cacabelos, Daniel; Aasprong, Ole Gunnar; Omdal, Roald; Svardal, Asbjørn M.; Bohov, Pavol; Pamplona, Reinald; Portero-Otin, Manuel; Berge, Rolf Kristian; Hausken, Trygve (Peer reviewed; Journal article, 2013-01-10)Fish oil (FO) has been shown to have anti-inflammatory properties in animal models of inflammatory bowel disease, but how fish peptides (FP) influence intestinal inflammation has been less studied. Male Wistar rats, divided ... -
A salmon protein hydrolysate exerts lipid-independent anti-atherosclerotic activity in apoE-deficient mice
Parolini, Cinzia; Vik, Rita; Busnelli, Marco; Bjørndal, Bodil; Holm, Sverre; Brattelid, Trond; Manzini, Stefano; Ganzetti, Giulia S.; Dellera, Federica; Halvorsen, Bente; Aukrust, Pål; Sirtori, Cesare R.; Nordrehaug, Jan Erik; Skorve, Jon; Berge, Rolf Kristian; Chiesa, Giulia (Peer reviewed; Journal article, 2014-05-19)Fish consumption is considered health beneficial as it decreases cardiovascular disease (CVD)-risk through effects on plasma lipids and inflammation. We investigated a salmon protein hydrolysate (SPH) that is hypothesized ... -
Serum Acylcarnitines and Risk of Cardiovascular Death and Acute Myocardial Infarction in Patients With Stable Angina Pectoris
Strand, Elin; Pedersen, Eva Ringdal; Svingen, Gard Frodahl Tveitevåg; Olsen, Thomas; Bjørndal, Bodil; Karlsson, Therese; Dierkes, Jutta; Njølstad, Pål Rasmus; Mellgren, Gunnar; Tell, Grethe S.; Berge, Rolf Kristian; Svardal, Asbjørn M.; Nygård, Ottar (Peer reviewed; Journal article, 2017-02)Background: Excess levels of serum acylcarnitines, which are intermediate products in metabolism, have been observed in metabolic diseases such as type 2 diabetes mellitus. However, it is not known whether acylcarnitines ... -
Sex-specific responses in glucose-insulin homeostasis and lipoprotein-lipid components after high-dose supplementation with marine n-3 PUFAs in abdominal obesity: a randomized double-blind crossover study
Laupsa-Borge, Johnny; Grytten, Elise; Bohov, Pavol; Bjørndal, Bodil; Strand, Elin; SKORVE, JON; Nordrehaug, Jan Erik; Berge, Rolf Kristian; Rostrup, Espen; Mellgren, Gunnar; Dankel, Simon N; Nygård, Ottar Kjell (Journal article; Peer reviewed, 2023)Background: Clinical studies on effects of marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and the plant-derived omega-6 (n-6) PUFA ... -
Short-term activation of peroxisome proliferator-activated receptors α and γ induces tissue-specific effects on lipid metabolism and fatty acid composition in male Wistar rats
Strand, Elin; Lysne, Vegard; Grinna, Mari Lausund; Bohov, Pavol; Svardal, Asbjørn M.; Nygård, Ottar; Berge, Rolf Kristian; Bjørndal, Bodil (Peer reviewed; Journal article, 2019-06-12)Dietary fatty acids (FAs) affect certain metabolic routes, including pathways controlled by the peroxisome proliferator-activated receptors (PPARs), but tissue-specific effects are not well-defined. Thus, the aim was to ... -
Short-term treatment with a peroxisome proliferator-activated receptor α agonist influences plasma one-carbon metabolites and B-vitamin status in rats
Lysne, Vegard; Bjørndal, Bodil; Grinna, Mari Lausund; Midttun, Øivind; Ueland, Per Magne; Berge, Rolf Kristian; Dierkes, Jutta; Nygård, Ottar; Strand, Elin (Peer reviewed; Journal article, 2019-12-05)Introduction: Peroxisome proliferator-activated receptors (PPARs) have been suggested to be involved in the regulation of one-carbon metabolism. Previously we have reported effects on plasma concentrations of metabolites ... -
Tetradecylthioacetic Acid Increases Hepatic Mitochondrial b-Oxidation and Alters Fatty Acid Composition in a Mouse Model of Chronic Inflammation
Burri, Lena; Bjørndal, Bodil; Wergedahl, Hege; Berge, Kjetil; Bohov, Pavol; Svardal, Asbjørn; Berge, Rolf Kristian (Peer reviewed; Journal article, 2011-04-09)The administration of tetradecylthioacetic acid (TTA), a hypolipidemic and anti-inflammatory modified bioactive fatty acid, has in several experiments based on high fat diets been shown to improve lipid transport and ... -
Tetradecylthiopropionic acid induces hepatic mitochondrial dysfunction and steatosis, accompanied by increased plasma homocysteine in mice
Berge, Rolf Kristian; Bjørndal, Bodil; Strand, Elin; Bohov, Pavol; Lindquist, Carine; Nordrehaug, Jan Erik; Svardal, Asbjørn; Skorve, Jon; Nygård, Ottar (Peer reviewed; Journal article, 2016-02-05)Background: Hepatic mitochondrial dysfunction plays an important role in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). Methyl donor supplementation has been shown to alleviate NAFLD, connecting the condition ... -
Three differently generated salmon protein hydrolysates reveal opposite effects on hepatic lipid metabolism in mice fed a high-fat diet
Vik, Rita; Tilander, Veronika; Skorve, Jon; Vihervaara, Terhi; Ekroos, Kim; Alexson, Stefan E.H.; Berge, Rolf Kristian; Bjørndal, Bodil (Peer reviewed; Journal article, 2015-03-17)This study investigates the effects of salmon peptide fractions, generated using different enzymatic hydrolyzation methods, on hepatic lipid metabolism. Four groups of mice were fed a high-fat diet with 20% casein (control ... -
Upregulated PDK4 expression is a sensitive marker of increased fatty acid oxidation
Pettersen, Ina Katrine Nitschke; Tusubira, Deusdedit; Ashrafi, Hanan; Dyrstad, Sissel Elisabeth; Hansen, Lena; Liu, Xiao-Zheng; Hodneland, Linn I.; Løvsletten, Nils Gunnar; Berge, Kjetil; Wergedahl, Hege; Bjørndal, Bodil; Fluge, Øystein; Bruland, Ove; Rustan, Arild; Halberg, Nils; Røsland, Gro Vatne; Berge, Rolf Kristian; Tronstad, Karl Johan (Peer reviewed; Journal article, 2019)Fatty acid oxidation is a central fueling pathway for mitochondrial ATP production. Regulation occurs through multiple nutrient- and energy-sensitive molecular mechanisms. We explored if upregulated mRNA expression of the ...