Browsing Faculty of Medicine by Journals "BMJ Open"
Now showing items 21-40 of 123
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Comparing the impact of upfront radiosurgery versus expectation in vestibular schwannoma (the V-REX study): protocol for a randomised, observer-blinded, 4-year, parallel-group, single-centre, superiority study
(Journal article; Peer reviewed, 2021)Introduction The optimal management of small-sized to medium-sized vestibular schwannoma (VS) is a matter of controversy. Clinical results of the prevailing treatment modalities (microsurgery, stereotactic radiosurgery ... -
Compliance with national guidelines for antibiotic prophylaxis in hip fracture patients: A quality assessment study of 13 329 patients in the Norwegian Hip Fracture Register
(Journal article; Peer reviewed, 2020)Objective We assessed compliance with new guidelines for prophylactic antibiotics in hip fracture surgery in Norway introduced in 2013. Design The data from the Norwegian Hip Fracture Register was used to assess the ... -
Continuity of care, measurement and association with hospital admission and mortality: a registry-based longitudinal cohort study
(Journal article; Peer reviewed, 2021)Objective To assess whether continuity of care (COC) with a general practitioner (GP) is associated with mortality and hospital admissions for older patients We argue that the conventional continuity measure may overestimate ... -
Contribution of an extensive medication-based comorbidity index (Rx-Risk) in explaining the excess mortality after hip fracture in older Norwegians: a NOREPOS cohort study
(Journal article; Peer reviewed, 2022)Objectives Patients with hip fracture are typically characterised by extensive comorbidities and excess mortality. Methods that account for a wide range of comorbidities are needed when attempting to identify causal ... -
Cost-effectiveness of household contact investigation for detection of tuberculosis in Pakistan
(Journal article; Peer reviewed, 2021)Objectives Despite WHO guidelines recommending household contact investigation, and studies showing the impact of active screening, most tuberculosis (TB) programmes in resource-limited settings only carry out passive ... -
Cost-effectiveness of running a paediatric oncology unit in Ethiopia
(Journal article; Peer reviewed, 2023)Objective: To estimate the cost-effectiveness of running a paediatric oncology unit in Ethiopia to inform the revision of the Ethiopia Essential Health Service Package (EEHSP), which ranks the treatment of childhood cancers ... -
Cost–utility analysis of antibiotic treatment in patients with chronic low back pain and Modic changes: results from a randomised, placebo-controlled trial in Norway (the AIM study)
(Journal article; Peer reviewed, 2020)Objective To evaluate the cost–utility of 100 days of antibiotics in patients with chronic low back pain (LBP) and type I or II Modic changes included in the Antibiotic treatment In patients with chronic low back pain ... -
Determining universal processes related to best outcome in emergency abdominal surgery: A multicentre, international, prospective cohort study
(Peer reviewed; Journal article, 2014-10-29)Introduction: Emergency abdominal surgery outcomes represent an internationally important marker of healthcare quality and capacity. In this study, a novel approach to investigating global surgical outcomes is proposed, ... -
Distributional impact of infectious disease interventions in the Ethiopian Essential Health Service Package: a modelling study
(Journal article; Peer reviewed, 2023)Objectives Reducing inequalities in health and financial risk are key goals on the path toward universal health coverage, particularly in low-income and middle-income countries. The design of the health benefit package ... -
Does caesarean delivery in the first pregnancy increase the risk for adverse outcome in the second? A registry-based cohort study on first and second singleton births in Norway
(Journal article; Peer reviewed, 2020)Objective To explore if newborns in the second pregnancy following a previous caesarean delivery (CD) have higher risk of perinatal mortality or cerebral palsy than newborns in pregnancies following a previous vaginal ... -
Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: Findings from the opinion-based PREDICT-FD modified Delphi consensus initiative
(Journal article; Peer reviewed, 2020)Objectives The PRoposing Early Disease Indicators for Clinical Tracking in Fabry Disease (PREDICT-FD) initiative aimed to reach consensus among a panel of global experts on early indicators of disease progression that may ... -
Effect of a specific exercise programme during pregnancy on diastasis recti abdominis: study protocol for a randomised controlled trial
(Journal article; Peer reviewed, 2022)Introduction: Diastasis recti abdominis (DRA) is a common condition in pregnant and postpartum women. Evidence for the treatment of DRA is both sparse and weak. As this condition occurs during the last two trimesters of ... -
The effect of guided self-determination on self-management in persons with type 1 diabetes mellitus and HbA1c ≥64 mmol/mol: a group-based randomised controlled trial
(Peer reviewed; Journal article, 2017)Objectives: To determine whether the impact of guided self-determination (GSD) applied in group training (GSD-GT) in people with chronically elevated HbA1c and type 1 diabetes mellitus (DM) was superior to ‘care as usual’ ... -
Effects of external inspection on sepsis detection and treatment: a study protocol for a quasiexperimental study with a stepped-wedge design
(Peer reviewed; Journal article, 2017)Introduction: Inspections are widely used in health care as a means to improve the health services delivered to patients. Despite their widespread use, there is little evidence of their effect. The mechanisms for how ... -
Effects of external inspections on sepsis detection and treatment: a stepped-wedge study With cluster-level randomisation
(Journal article; Peer reviewed, 2020)Objective To evaluate the effects of external inspections on (1) hospital emergency departments’ clinical processes for detecting and treating sepsis and (2) length of hospital stay and 30-day mortality. Design Incomplete ... -
The effects of vitamin B12 supplementation in pregnancy and postpartum on growth and neurodevelopment in early childhood: Study Protocol for a Randomized Placebo Controlled Trial
(Peer reviewed; Journal article, 2017)Introduction: Vitamin B12 is crucial for normal cell division and differentiation, and necessary for the development and myelination of the central nervous system. Pregnant mothers in resource poor settings are at risk for ... -
Efficacy of low-level laser therapy in patients with lower extremity tendinopathy or plantar fasciitis: systematic review and meta-analysis of randomised controlled trials
(Journal article; Peer reviewed, 2022)Objectives We investigated the effectiveness of low-level laser therapy (LLLT) in lower extremity tendinopathy and plantar fasciitis on patient-reported pain and disability. Design Systematic review and meta-analysis. Data ... -
Efficacy of low-level laser therapy on pain and disability in knee osteoarthritis: Systematic review and meta-analysis of randomised placebo-controlled trials
(Peer reviewed; Journal article, 2019)Objectives: Low-level laser therapy (LLLT) is not recommended in major knee osteoarthritis (KOA) treatment guidelines. We investigated whether a LLLT dose–response relationship exists in KOA. Design: Systematic review ... -
Efficacy of mobilisation with movement in chronic shoulder pain: protocol for a systematic review and meta-analysis of controlled trials
(Journal article; Peer reviewed, 2021)Introduction Shoulder pain affects approximately one in four adults and is thus one of the most common musculoskeletal problems. Only 50% of patients who begin treatment for shoulder pain are cured within 6 months. There ... -
Ethics and legal requirements for data linkage in 14 European countries for children with congenital anomalies
(Journal article; Peer reviewed, 2023)Introduction: Linking healthcare data sets can create valuable resources for research, particularly when investigating rare exposures or outcomes. However, across Europe, the permissions processes required to access data ...