Browsing Faculty of Medicine by Author "Dale, Hege Avsnes"
Now showing items 1-3 of 3
-
Evidence for the role of Rab11-positive recycling endosomes as intermediates in coronavirus egress from epithelial cells
Saraste, Jaakko; Enyioko, Mary; Dale, Hege Avsnes; Prydz, Kristian; Machamer, Carolyn (Journal article; Peer reviewed, 2022)After their assembly by budding into the lumen of the intermediate compartment (IC) at the endoplasmic reticulum (ER)–Golgi interface, coronaviruses (CoVs) are released from their host cells following a pathway that remains ... -
In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways
Daphu, Inderjit Kaur; Horn, Sindre August; Stieber, Daniel; Varughese, Jobin K.; Spriet, Endy; Dale, Hege Avsnes; Skaftnesmo, Kai Ove; Bjerkvig, Rolf; Thorsen, Frits Alan (Peer reviewed; Journal article, 2014-05-16)Malignant melanoma is the most lethal form of skin cancer, with a high propensity to metastasize to the brain. More than 60% of melanomas have the BRAFV600E mutation, which activates the mitogen-activated protein kinase ... -
A new live-cell reporter strategy to simultaneously monitor mitochondrial biogenesis and morphology
Hodneland, Linn I.; Pettersen, Ina Katrine Nitschke; Nikolaisen, Julie; Micklem, David Robert; Dale, Hege Avsnes; Røsland, Gro Vatne; Lorens, James; Tronstad, Karl Johan (Peer reviewed; Journal article, 2015-11-24)Changes in mitochondrial amount and shape are intimately linked to maintenance of cell homeostasis via adaptation of vital functions. Here, we developed a new live-cell reporter strategy to simultaneously monitor mitochondrial ...