Browsing Faculty of Medicine by Journals "BMC Structural Biology"
Now showing items 1-3 of 3
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The Host-Pathogen interaction of Human Cyclophilin A and HIV-1 Vpr requires specific N-terminal and novel C-terminal domains
(Peer reviewed; Journal article, 2011-12-20)Background: Cyclophilin A (CypA) represents a potential key molecule in future antiretroviral therapy since inhibition of CypA suppresses human immunodeficiency virus type 1 (HIV-1) replication. CypA interacts with the ... -
Structure and dynamics of a human myelin protein P2 portal region mutant indicate opening of the β barrel in fatty acid binding proteins
(Peer reviewed; Journal article, 2018-06-25)Background: Myelin is a multilayered proteolipid sheath wrapped around selected axons in the nervous system. Its constituent proteins play major roles in forming of the highly regular membrane structure. P2 is a myelin-specific ... -
A three dimensional visualisation approach to protein heavy-atom structure reconstruction
(Peer reviewed; Journal article, 2014-12-31)Background: A commonly recurring problem in structural protein studies, is the determination of all heavy atom positions from the knowledge of the central α-carbon coordinates. Results: We employ advances in virtual reality ...