Browsing Faculty of Medicine by Journals "Breast Cancer Research and Treatment"
Now showing items 1-8 of 8
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Differences in metastatic patterns in relation to time between primary surgery and first relapse from breast cancer suggest synchronized growth of dormant micrometastases
(Peer reviewed; Journal article, 2014-08)A significant variation in the metastatic pattern among breast cancer patients exists. Clinical observations suggest that these differences are related to time to recurrence (TTR), thus suggesting a common systemic growth ... -
Exploring the effects of lifestyle on breast cancer risk, age at diagnosis, and survival: the EBBA-Life study
(Journal article; Peer reviewed, 2020)Purpose Whether an unfavorable lifestyle not only affects breast cancer risk, but also influences age at onset of breast cancer and survival, is under debate. Methods In a population-based cohort, the Energy Balance ... -
FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis
(Peer reviewed; Journal article, 2017-04)Purpose: Proliferation is a hallmark of cancer. Using a combined genomic approach, FGD5 amplification has been identified as a driver of proliferation in Luminal breast cancer. We aimed to describe FGD5 copy number change ... -
High PTEN gene expression is a negative prognostic marker in human primary breast cancers with preserved p53 function
(Peer reviewed; Journal article, 2017)Purpose: PTEN is an important tumor suppressor in breast cancer. Here, we examined the prognostic and predictive value of PTEN and PTEN pseudogene (PTENP1) gene expression in patients with locally advanced breast cancer ... -
MRPS23 amplification and gene expression in breast cancer; association with proliferation and the non-basal subtypes
(Journal article; Peer reviewed, 2020-01-16)Purpose MRPS23 is recognized as a driver of proliferation in luminal breast cancer. The aims of the present study were to describe MRPS23 copy number change in breast cancer, and to assess associations between MRPS23 copy ... -
Prognostic and predictive impact of stroma cells defned by PDGFRb expression in early breast cancer: results from the randomized SweBCG91RT trial
(Journal article; Peer reviewed, 2021)Purpose Predictive biomarkers are needed to aid the individualization of radiotherapy (RT) in breast cancer. Cancer-associated fibroblasts have been implicated in tumor radioresistance and can be identified by platelet-derived ... -
The recurrence pattern following delayed breast reconstruction after mastectomy for breast cancer suggests a systemic effect of surgery on occult dormant micrometastases
(Peer reviewed; Journal article, 2016)The purpose of this study was to characterize the recurrence dynamics in breast cancer patients after delayed reconstruction. We hypothesized that surgical reconstruction might stimulate dormant micrometastases and reduce ... -
Vessel size as a marker of survival in estrogen receptor positive breast cancer
(Journal article; Peer reviewed, 2023)Purpose: Angiogenesis is crucial for tumor growth and is one of the hallmarks of cancer. In this study, we analyzed microvessel density, vessel median size, and perivascular a-SMA expression as prognostic biomarkers in ...