Browsing Faculty of Medicine by Subject "APS-1"
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Oral microbiota in autoimmune polyendocrine syndrome type 1
(Peer reviewed; Journal article, 2018)Background: Autoimmune polyendocrine syndrome type-1 (APS-1) is a rare, childhood onset disease caused by mutations in the Autoimmune Regulator gene. The phenotypic expression is highly variable and includes disease ... -
Sensing foul AIRE: Investigating possible reporter genes for AIRE mutations
(Master thesis, 2018-06-29)The autoimmune regulator protein, known as AIRE, is a potent transcriptional regulator active in medullary thymic epithelial cells (mTECs) of the thymus, where it is able to switch on the expression of thousands of genes ...