Blar i Faculty of Medicine på forfatter "Anandan, Shamundeeswari"
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CD24-targeted fluorescence imaging in patient-derived xenograft models of high-grade serous ovarian carcinoma
Kleinmanns, Katrin; Bischof, Katharina; Anandan, Shamundeeswari; Popa, Mihaela Lucia; Akslen, Lars A.; Gjertsen, Bjørn Tore; Karlsen, Ida; Fosse, Vibeke Samuelsen; Bjørge, Line; Mc Cormack, Emmet (Journal article; Peer reviewed, 2020)Background The survival rate of patients with advanced high-grade serous ovarian carcinoma (HGSOC) remains disappointing. Clinically translatable orthotopic cell line xenograft models and patient-derived xenografts (PDXs) ... -
Combining Mass Cytometry Data by CyTOFmerge Reveals Additional Cell Phenotypes in the Heterogeneous Ovarian Cancer Tumor Microenvironment: A Pilot Study
Thomsen, Liv Cecilie Vestrheim; Kleinmanns, Katrin; Anandan, Shamundeeswari; Gullaksen, Stein-Erik; Abdelaal, Tamim; Iversen, Grete Alræk; Akslen, Lars Andreas; Mc Cormack, Emmet; Bjørge, Line (Journal article; Peer reviewed, 2023-10-23)The prognosis of high-grade serous ovarian carcinoma (HGSOC) is poor, and treatment selection is challenging. A heterogeneous tumor microenvironment (TME) characterizes HGSOC and influences tumor growth, progression, and ... -
Phenotypic Characterization by Mass Cytometry of the Microenvironment in Ovarian Cancer and Impact of Tumor Dissociation Methods
Anandan, Shamundeeswari; Thomsen, Liv Cecilie Vestrheim; Gullaksen, Stein-Erik; Abdelaal, Tamim; Kleinmanns, Katrin; Skavland, Jørn; Bredholt, Geir; Gjertsen, Bjørn Tore; Cormack, Emmet Mc; Bjørge, Line (Journal article; Peer reviewed, 2021)Improved molecular dissection of the tumor microenvironment (TME) holds promise for treating high-grade serous ovarian cancer (HGSOC), a gynecological malignancy with high mortality. Reliable disease-related biomarkers are ... -
“Rethinking High-Grade Serous Carcinoma: Development of new tools for deep tissue profiling”
Anandan, Shamundeeswari (Doctoral thesis, 2021-09-03)Background: High-grade serous ovarian cancer (HGSOC) is the most frequently occurring and most fatal epithelial ovarian cancer (EOC) subtype. The reciprocal interplay of the different components encompassed within the ...