Blar i Faculty of Medicine på forfatter "Burger, Bram"

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    • Analyzing the Structure of Pathways and Its Influence on the Interpretation of Biomedical Proteomics Data Sets 

      Burger, Bram; Hernández Sánchez, Luis Francisco; Lereim, Ragnhild Reehorst; Barsnes, Harald; Vaudel, Marc (Peer reviewed; Journal article, 2018)
      Biochemical pathways are commonly used as a reference to conduct functional analysis on biomedical omics data sets, where experimental results are mapped to knowledgebases comprising known molecular interactions collected ...

    • Automated splitting into batches for observational biomedical studies with sequential processing 

      Burger, Bram; Vaudel, Marc; Barsnes, Harald (Journal article; Peer reviewed, 2022)
      Experimental design usually focuses on the setting where treatments and/or other aspects of interest can be manipulated. However, in observational biomedical studies with sequential processing, the set of available samples ...

    • Extending protein interaction networks using proteoforms and small molecules 

      Sanchez, Luis Francisco Hernandez; Burger, Bram; Campos, Rodrigo Alexander Castro; Johansson, Stefan; Njølstad, Pål Rasmus; Barsnes, Harald; Vaudel, Marc (Journal article; Peer reviewed, 2023)
      Motivation: Biological network analysis for high-throughput biomedical data interpretation relies heavily on topological characteristics. Networks are commonly composed of nodes representing genes or proteins that are ...

    • PathwayMatcher: proteoform-centric network construction enables fine-granularity multi-omics pathway mapping 

      Hernández Sánchez, Luis Francisco; Burger, Bram; Horro Marcos, Carlos; Fabregat, Antonio; Johansson, Stefan; Njølstad, Pål Rasmus; Barsnes, Harald; Hermjakob, Henning; Vaudel, Marc (Peer reviewed; Journal article, 2019-07-30)
      Background Mapping biomedical data to functional knowledge is an essential task in bioinformatics and can be achieved by querying identifiers (e.g., gene sets) in pathway knowledge bases. However, the isoform and ...