Browsing Faculty of Medicine by Author "Maag, Jesper L.V."

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    • Dynamic expression of long noncoding RNAs and repeat elements in synaptic plasticity 

      Maag, Jesper L.V.; Panja, Debabrata; Sporild, Ida; Patil, Sudarshan; Kaczorowski, Dominik C.; Bramham, Clive R.; Dinger, Marcel E.; Wibrand, Karin (Peer reviewed; Journal article, 2015-10-01)
      Long-term potentiation (LTP) of synaptic transmission is recognized as a cellular mechanism for learning and memory storage. Although de novo gene transcription is known to be required in the formation of stable LTP, the ...

    • Widespread promoter methylation of synaptic plasticity genes in long-term potentiation in the adult brain in vivo. 

      Maag, Jesper L.V.; Kaczorowski, Dominik C.; Panja, Debabrata; Peters, Timothy J.; Bramham, Clive R.; Wibrand, Karin; Dinger, Marcel E. (Peer reviewed; Journal article, 2017-03-23)
      Background: DNA methylation is a key modulator of gene expression in mammalian development and cellular differentiation, including neurons. To date, the role of DNA modifications in long-term potentiation (LTP) has not ...