Browsing Faculty of Medicine by Journals "F1000 Research"

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Case Report: Polyvinylpyrrolidone deposition disease from repeated injection of opioid substitution drugs: Report of a case with a fatal outcome

Stalund, Ida Viken; Riise, Gro Nygard; Leh, Friedemann; Bjånes, Tormod Karlsen; Riise, Lars; Svarstad, Einar; Leh, Sabine (Journal article; Peer reviewed, 2021)

Background: Intravenous injection of oral opioid substitution drugs (OSD) is widespread among injecting drug users. Several OSDs contain the polymer polyvinylpyrrolidone (PVP) as an excipient. Parenterally administered PVP ...
Toward understanding scarless skin wound healing and pathological scarring

Karppinen, Sanna-Maria; Heljasvaara, Ritva Leena; Gullberg, Donald; Tasanen, Kaisa; Pihlajaniemi, Taina (Peer reviewed; Journal article, 2019)

The efficient healing of skin wounds is crucial for securing the vital barrier function of the skin, but pathological wound healing and scar formation are major medical problems causing both physiological and psychological ...