Blar i Faculty of Medicine på tidsskrift "Frontiers in Molecular Neuroscience"
Viser treff 1-4 av 4
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Chip protein U-box domain truncation affects Purkinje neuron morphology and leads to behavioral changes in zebrafish
(Journal article; Peer reviewed, 2021-09-24)The ubiquitin ligase CHIP (C-terminus of Hsc70-interacting protein) is encoded by STUB1 and promotes ubiquitination of misfolded and damaged proteins. CHIP deficiency has been linked to several diseases, and mutations in ... -
Detection of Arc/Arg3.1 oligomers in rat brain: constitutive and synaptic activity-evoked dimer expression in vivo
(Journal article; Peer reviewed, 2023)The immediate early gene product activity-regulated cytoskeleton-associated protein (Arc or Arg3.1) is a major regulator of long-term synaptic plasticity with critical roles in postnatal cortical development and memory ... -
Direct Binding of the Flexible C-Terminal Segment of Periaxin to β4 Integrin Suggests a Molecular Basis for CMT4F
(Peer reviewed; Journal article, 2019-04-09)The process of myelination in the nervous system requires a coordinated formation of both transient and stable supramolecular complexes. Myelin-specific proteins play key roles in these assemblies, which may link membranes ... -
GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation
(Peer reviewed; Journal article, 2017-06-16)The selective and neuronal activity-dependent degradation of synaptic proteins appears to be crucial for long-term synaptic plasticity. One such protein is activity-regulated cytoskeleton-associated protein (Arc), which ...