Browsing Faculty of Medicine by Journals "Matrix Biology"

Now showing items 1-3 of 3

    • The extostosin family: Proteins with many functions 

      Busse-Wicher, Marta; Wicher, Krzysztof B.; Kusche-Gullberg, Marion (Peer reviewed; Journal article, 2014-04)
      Heparan sulfates are complex sulfated molecules found in abundance at cell surfaces and in the extracellular matrix. They bind to and influence the activity of a variety of molecules like growth factors, proteases and ...

    • Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis 

      Wang, Yuanyuan; Liu, Xiaobo; Obser, Tobias; Bauer, Alexander T.; Heyes, Martin; Starzonek, Sarah; Zulal, Mina; Opitz, Karena; Ott, Leonie; Riethdorf, Sabine; Lange, Tobias; Pantel, Klaus; Bendas, Gerd; Schneider, Stefan W.; Gullberg, Marion Kusche; Gorzelanny, Christian (Journal article; Peer reviewed, 2022)
      Heparan sulfate (HS), a highly negatively charged glycosaminoglycan, is ubiquitously present in all tissues and also exposed on the surface of mammalian cells. A plethora of molecules such as growth factors, cytokines or ...

    • Post-translational modifications of integrin ligands as pathogenic mechanisms in disease 

      Zeltz, Cedric; Gullberg, Donald (Peer reviewed; Journal article, 2014-11)
      Protein post-translational modifications like glycation, carbamylation and citrullination increase the functional diversity of the proteome but in disease situations might do more harm than good. Post-translational ...