Blar i Faculty of Medicine på tidsskrift "Neuro-Oncology"
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Cancer cell heterogeneity and plasticity: A paradigm shift in glioblastoma
(Journal article; Peer reviewed, 2022)Phenotypic plasticity has emerged as a major contributor to intra-tumoral heterogeneity and treatment resistance in cancer. Increasing evidence shows that glioblastoma (GBM) cells display prominent intrinsic plasticity and ... -
Long-term treatment with valganciclovir improves lentiviral suicide gene therapy of glioblastoma
(Peer reviewed; Journal article, 2019)Background: Suicide gene therapy for malignant gliomas has shown encouraging results in the latest clinical trials. However, prodrug application was most often restricted to short-term treatment (14 days), especially when ... -
Surgical resection of glioblastomas induces pleiotrophin-mediated self-renewal of glioblastoma stem cells in recurrent tumors
(Journal article; Peer reviewed, 2022)Background Glioblastomas are highly resistant to therapy, and virtually all patients experience tumor recurrence after standard-of-care treatment. Surgical tumor resection is a cornerstone in glioblastoma therapy, but its ...