Blar i Faculty of Medicine på tidsskrift "Theranostics"
Viser treff 1-2 av 2
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Repurposing 18F-FMISO as a PET tracer for translational imaging of nitroreductase-based gene directed enzyme prodrug therapy
(Journal article; Peer reviewed, 2021)Nitroreductases (NTR) are a family of bacterial enzymes used in gene directed enzyme prodrug therapy (GDEPT) that selectively activate prodrugs containing aromatic nitro groups to exert cytotoxic effects following gene ... -
Targeting the splicing factor NONO inhibits GBM progression through GPX1 intron retention
(Journal article; Peer reviewed, 2022)Background: Splicing factors are essential for nascent pre-mRNA processing and critical in cancer progression, suggesting that proteins with splicing functions represent potential molecular targets for cancer therapy. Here, ...