Browsing Department of Biomedicine by Journals "Cells"
Now showing items 1-5 of 5
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Assembly and Cellular Exit of Coronaviruses: Hijacking an Unconventional Secretory Pathway from the Pre-Golgi Intermediate Compartment via the Golgi Ribbon to the Extracellular Space
(Journal article; Peer reviewed, 2021)Coronaviruses (CoVs) assemble by budding into the lumen of the intermediate compartment (IC) at the endoplasmic reticulum (ER)-Golgi interface. However, why CoVs have chosen the IC as their intracellular site of assembly ... -
Collagen Assembly at the Cell Surface: Dogmas Revisited
(Journal article; Peer reviewed, 2021)With the increased awareness about the importance of the composition, organization, and stiffness of the extracellular matrix (ECM) for tissue homeostasis, there is a renewed need to understand the details of how cells ... -
Epac1 Is Crucial for Maintenance of Endothelial Barrier Function through A Mechanism Partly Independent of Rac1
(Journal article; Peer reviewed, 2020)Epac1 (exchange protein activated by cAMP) stabilizes the endothelial barrier, but detailed studies are limited by the side effects of pharmacological Epac1 modulators and transient transfections. Here, we compare the key ... -
Flexible Players within the Sheaths: The Intrinsically Disordered Proteins of Myelin in Health and Disease
(Journal article; Peer reviewed, 2020)Myelin ensheathes selected axonal segments within the nervous system, resulting primarily in nerve impulse acceleration, as well as mechanical and trophic support for neurons. In the central and peripheral nervous systems, ... -
How Does Protein Zero Assemble Compact Myelin?
(Journal article; Peer reviewed, 2020-08)Myelin protein zero (P0), a type I transmembrane protein, is the most abundant protein in peripheral nervous system (PNS) myelin—the lipid-rich, periodic structure of membrane pairs that concentrically encloses long axonal ...