• Degradation of Extracellular NAD+ Intermediates in Cultures of Human HEK293 Cells 

      Kulikova, Veronika; Shabalin, Konstantin; Nerinovski, Kirill; Yakimov, Alexander; Svetlova, Maria; Solovjeva, Ljudmila; Kropotov, Andrey; Khodorkovskiy, Mikhail; Migaud, Marie E.; Ziegler, Mathias; Nikiforov, Andrey (Peer reviewed; Journal article, 2019-11-29)
      Nicotinamide adenine dinucleotide (NAD) is an essential redox carrier, whereas its degradation is a key element of important signaling pathways. Human cells replenish their NAD contents through NAD biosynthesis from ...
    • Early Evolutionary Selection of NAD Biosynthesis Pathway in Bacteria 

      Sharma, Suraj; Hsieh, Yin-Chen; Dietze, Jørn; Bockwoldt, Mathias; Strømland, Øyvind; Ziegler, Mathias; Heiland, Ines (Journal article; Peer reviewed, 2022)
      Bacteria use two alternative pathways to synthesize nicotinamide adenine dinucleotide (NAD) from nicotinamide (Nam). A short, two-step route proceeds through nicotinamide mononucleotide (NMN) formation, whereas the other ...