Browsing Department of Biomedicine by Subject "VDP::Medical sciences: 700::Basic medical, dental and veterinary sciences: 710::Medical molecular biology: 711"
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HAMLET forms annular oligomers when deposited with phoshpolipid monolayers
(Peer reviewed; Journal article, 2012-04)Recently, the anticancer activity of human α-lactalbumin made lethal to tumor cells (HAMLET) has been linked to its increased membrane affinity in vitro, at neutral pH, and ability to cause leakage relative to the inactive ... -
In vitro treatment of melanoma brain metastasis by simultaneously targeting the MAPK and PI3K signaling pathways
(Peer reviewed; Journal article, 2014-05-16)Malignant melanoma is the most lethal form of skin cancer, with a high propensity to metastasize to the brain. More than 60% of melanomas have the BRAFV600E mutation, which activates the mitogen-activated protein kinase ...