Blar i Department of Global Public Health and Primary Care på forfatter "Nilsen, Roy Miodini"
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450K epigenome-wide scan identifies differential DNA methylation in newborns related to maternal smoking during pregnancy
Joubert, Bonnie R.; Håberg, Siri Eldevik; Nilsen, Roy Miodini; Wang, Xuting; Vollset, Stein Emil; Murphy, Susan K; Huang, Zhiqing; Hoyo, Cathrine; Midttun, Øivind; Cupul-Uicab, Lea A; Ueland, Per Magne; Wu, Michael C; Nystad, Wenche; Bell, Douglas A; Peddada, Shyamal D; London, Stephanie J (Peer reviewed; Journal article, 2012-10)Background: Epigenetic modifications, such as DNA methylation, due to in utero exposures may play a critical role in early programming for childhood and adult illness. Maternal smoking is a major risk factor for multiple ... -
The ability of the Ages and Stages Questionnaire (ASQ) to indicate motor difficulties in infants in primary care
Tveten, Kine Melfald; Strand, Liv Inger; Riiser, Kirsti; Nilsen, Roy Miodini; Dragesund, Tove (Journal article; Peer reviewed, 2022)Introduction Delayed achievement of motor milestones may be an early indicator of motor difficulties. Parent-reported questionnaires may serve as an efficient, low-cost screening to identify infants in need of further ... -
Adjusting for outcome risk factors in immigrant datasets: total or direct effects?
Nilsen, Roy Miodini; Klungsøyr, Kari; Stigum, Hein (Journal article; Peer reviewed, 2023)Background When quantifying differences in health outcomes between immigrants and non-immigrants, it is common practice to adjust for observed differences in outcome risk factors between the groups being compared. However, ... -
Being overweight in childhood, puberty, or early adulthood: Changing asthma risk in the next generation?
Johannessen, Ane; Lønnebotn, Marianne; Calciano, Lucia; Benediktsdóttir, Bryndís; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Dharmage, Shyamali; Franklin, Karl A.; Gíslason, Þórarinn; Holm, Mathias; Janson, Christer; Jarvis, Deborah; Jõgi, Rain; Kim, Jeong-Lim; Kirkeleit, Jorunn; Lodge, Caroline; Malinovschi, Andrei; Martinez-Moratalla, Jesus; Nilsen, Roy Miodini; Pereira-Vega, Antonio; Gomez Real, Francisco; Schlünssen, Vivi; Accordini, Simone; Svanes, Cecilie (Peer reviewed; Journal article, 2020-03)Background Overweight status and asthma have increased during the last decades. Being overweight is a known risk factor for asthma, but it is not known whether it might also increase asthma risk in the next generation. ... -
Cohort profile: Outcomes & Multi-morbidity In Type 2 diabetes (OMIT) – a national registry-based observational cohort with focus on care and treatment of key high-risk groups in Norway
Forster, Rachel Bedenis; Strandberg, Ragnhild Bjarkøy; Tibballs, Katrina Louise Bø; Nøkleby, Kjersti; Berg, Tore Julsrud; Iversen, Tor; Hagen, Terje P.; Richardsen, Kåre Rønn; Cooper, John; Sandberg, Sverre; Løvaas, Karianne Fjeld; Nilsen, Roy Miodini; Iversen, Marjolein M.; Jenum, Anne Karen; Buhl, Esben Selmer (Journal article; Peer reviewed, 2022)Purpose The ‘Outcomes & Multi-morbidity in Type 2 Diabetes’ (OMIT) is an observational registry-based cohort of Norwegian patients with type 2 diabetes (T2D) established to study high-risk groups often omitted from randomised ... -
Country of first birth and neonatal outcomes in migrant and Norwegian-born parous women in Norway: a population-based study
Vik, Eline Skirnisdottir; Nilsen, Roy Miodini; Aasheim, Vigdis; Small, Rhonda; Moster, Dag; Schytt, Erica (Journal article; Peer reviewed, 2020)Background This study compares subsequent birth outcomes in migrant women who had already had a child before arriving in Norway with those in migrant women whose first birth occurred in Norway. The aim of this study was ... -
Diet matters, particularly in pregnancy - results from MoBa studies of maternal diet and pregnancy outcomes
Brantsæter, Anne Lise; Haugen, Margaretha; Myhre, Ronny; Sengpiel, Verena; Englund-Ögge, Linda; Nilsen, Roy Miodini; Borgen, Iren; Duarte-Salles, Talita; Papadopoulou, Eleni; Vejrup, Kristine; von Ruesten, Anne; Hillesund, Elisabet Rudjord; Birgisdottir, Bryndis Eva; Magnus, Per; Trogstad, Lill; Jacobsson, Bo; Bacelis, Jonas; Myking, Solveig; Knutsen, Helle Katrine; Kvalem, Helen Engelstad; Alexander, Jan; Mendez, Michelle; Meltzer, Helle Margrete (Peer reviewed; Journal article, 2014)Awareness that maternal diet may influence the outcome of pregnancy as well as the long-term health of mother and child has increased in recent years. A new food frequency questionnaire (FFQ) was developed and validated ... -
Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study
Husabø, Gunnar; Nilsen, Roy Miodini; Flaatten, Hans; Solligård, Erik; Frich, Jan C; Bondevik, Gunnar Tschudi; Braut, Geir Sverre; Walshe, Kieran; Harthug, Stig; Hovlid, Einar (Peer reviewed; Journal article, 2020-01-22)Background: Early recognition of sepsis is critical for timely initiation of treatment. The first objective of this study was to assess the timeliness of diagnostic procedures for recognizing sepsis in emergency departments. ... -
Effects of external inspection on sepsis detection and treatment: a study protocol for a quasiexperimental study with a stepped-wedge design
Hovlid, Einar; Frich, Jan C; Walshe, Kieran; Nilsen, Roy Miodini; Flaatten, Hans; Braut, Geir Sverre; Helgeland, Jon; Teig, Inger Lise; Harthug, Stig (Peer reviewed; Journal article, 2017)Introduction: Inspections are widely used in health care as a means to improve the health services delivered to patients. Despite their widespread use, there is little evidence of their effect. The mechanisms for how ... -
Effects of external inspections on sepsis detection and treatment: a stepped-wedge study With cluster-level randomisation
Husabø, Gunnar; Nilsen, Roy Miodini; Solligård, Erik; Flaatten, Hans; Walshe, Kieran; Frich, Jan C; Bondevik, Gunnar Tschudi; Braut, Geir Sverre; Helgeland, Jon; Harthug, Stig; Hovlid, Einar (Journal article; Peer reviewed, 2020)Objective To evaluate the effects of external inspections on (1) hospital emergency departments’ clinical processes for detecting and treating sepsis and (2) length of hospital stay and 30-day mortality. Design Incomplete ... -
Electronic capturing of patient-reported outcome measures on a touchscreen computer in clinical diabetes practice (the DiaPROM trial): a feasibility study
Hernar, Ingvild; Graue, Marit; Richards, David A; Strandberg, Ragnhild Bjarkøy; Nilsen, Roy Miodini; Tell, Grethe S.; Haugstvedt, Anne (Peer reviewed; Journal article, 2019-02-20)Background: Living with type 1 diabetes (T1D) is demanding, and emotional problems may impair ability for diabetes self-management. Thus, diabetes guidelines recommend regular assessment of such problems. Using patient-reported ... -
Epidural analgesia for labour pain in nulliparous women in Norway in relation to maternal country of birth and migration related factors
Aasheim, Vigdis; Nilsen, Roy Miodini; Vik, Eline Skirnisdottir; Small, Rhonda; Schytt, Erica (Journal article; Peer reviewed, 2020)Objective To investigate associations between maternal country of birth and other migration related factors (length of residence, reason for migration, paternal origin) and epidural analgesia for labour pain in nulliparous ... -
Factors associated with change in health-related quality of life among individuals treated with long-term mechanical ventilation, a 6-year follow-up study
Markussen, Heidi Øksnes; Lehmann, Sverre; Nilsen, Roy Miodini; Natvig, Gerd Karin (Peer reviewed; Journal article, 2018-03)Aims: To examine changes and explanatory variables for changes in health-related quality of life in patients treated with long-term mechanical ventilation over a 6-year period. Background: Long-term mechanical ventilation ... -
Folate and reproductive health. An epidemiologic study of folic acid supplement use and its relation to birth outcomes in Norwegian pregnant women
Nilsen, Roy Miodini (Doctoral thesis, 2010-04-23)Background: Randomized trials and observational studies have consistently shown that maternal intake of folic acid supplements before and early in pregnancy reduces the risk of neural tube defects in infants. These reports ... -
Folic acid supplementation, dietary folate intake during pregnancy and risk for spontaneous preterm delivery: a prospective observational cohort study
Sengpiel, Verena; Bacelis, Jonas; Myhre, Ronny; Myking, Solveig; Pay, Aase Serine Devold; Haugen, Margaretha; Brantsæter, Anne Lise; Meltzer, Helle Margrethe; Nilsen, Roy Miodini; Magnus, Per; Vollset, Stein Emil; Nilsson, Staffan; Jacobsson, Bo (Peer reviewed; Journal article, 2014-11-02)Background: Health authorities in numerous countries recommend periconceptional folic acid supplementation to prevent neural tube defects. The objective of this study was to examine the association of dietary folate intake ... -
Gestational diabetes mellitus by maternal country of birth and length of residence in immigrant women in Norway
Strandberg, Ragnhild Bjarkøy; Iversen, Marjolein M.; Jenum, Anne Karen; Sørbye, Linn Marie; Vik, Eline Skirnisdottir; Schytt, Erica; Aasheim, Vigdis; Nilsen, Roy Miodini (Journal article; Peer reviewed, 2021)Aims: Immigrant women are at higher risk for gestational diabetes mellitus (GDM) than non-immigrant women. This study described the prevalence of GDM in immigrant women by maternal country of birth and examined the ... -
Health-related quality of life as predictor for mortality in patients treated with long-term mechanical ventilation
Markussen, Heidi Øksnes; Lehmann, Sverre; Nilsen, Roy Miodini; Natvig, Gerd Karin (Peer reviewed; Journal article, 2019-01-11)Background The Severe Respiratory Insufficiency (SRI) questionnaire is a specific measure of health-related quality of life (HRQoL) in patients treated with long-term mechanical ventilation (LTMV). The aim of the present ... -
Increased incidence of postoperative infections during prophylaxis with cephalothin compared to doxycycline in intestinal surgery
Baatrup, Gunnar; Nilsen, Roy Miodini; Svensen, Rune; Akselsen, Per E. (Peer reviewed; Journal article, 2009-12-07)Background: The antibiotics used for prophylaxis during surgery may influence the rate of surgical site infections. Tetracyclines are attractive having a long half-life and few side effects when used in a single dose ... -
Lifelong exposure to air pollution and greenness in relation to asthma, rhinitis and lung function in adulthood
Kuiper, Ingrid Nordeide; Svanes, Cecilie; Markevych, Iana; Accordini, Simone; Bertelsen, Randi Jacobsen; Bråbäck, Lennart; Christensen, Jesper Heile; Forsberg, Bertil; Halvorsen, Thomas; Heinrich, Joachim; Hertel, Ole; Hoek, Gerard; Holm, Mathias; De Hoogh, Kees; Janson, Christer; Malinovschi, Andrei; Marcon, Alessandro; Nilsen, Roy Miodini; Sigsgaard, Torben; Johannessen, Ane (Journal article; Peer reviewed, 2021)Objectives To investigate if air pollution and greenness exposure from birth till adulthood affects adult asthma, rhinitis and lung function. Methods: We analysed data from 3428 participants (mean age 28) in the RHINESSA ... -
Lower education and immigrant background are associated with lower participation in a diabetes education program - Insights from adult patients in the Outcomes & Multi-morbidity In Type 2 diabetes cohort (OMIT)
Strandberg, Ragnhild Bjarkøy; Nilsen, Roy Miodini; Pouwer, Frans; Igland, Jannicke; Forster, Rachel Bedenis; Jenum, Anne Karen; Buhl, Esben Selmer; Iversen, Marjolein Memelink (Journal article; Peer reviewed, 2023)Objectives Diabetes educational programmes should be offered to patients with type 2 diabetes mellitus (T2DM). We assessed the proportion of diabetes educational program participation among adults with T2DM, and its ...