Browsing Department of Global Public Health and Primary Care by Journals "BMC Bioinformatics"
Now showing items 1-3 of 3
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Detecting diferentially methylated regions using a fast wavelet‑based approach to functional association analysis
(Journal article; Peer reviewed, 2021)Background We present here a computational shortcut to improve a powerful wavelet-based method by Shim and Stephens (Ann Appl Stat 9(2):665–686, 2015. https://doi.org/10.1214/14-AOAS776) called WaveQTL that was originally ... -
Haplin power analysis: a software module for power and sample size calculations in genetic association analyses of family triads and unrelated controls
(Peer reviewed; Journal article, 2019-04-02)Background: Log-linear and multinomial modeling offer a flexible framework for genetic association analyses of offspring (child), parent-of-origin and maternal effects, based on genotype data from a variety of child-parent ... -
Wavelet Screening: a novel approach to analyzing GWAS data
(Journal article; Peer reviewed, 2021)Background Traditional methods for single-variant genome-wide association study (GWAS) incur a substantial multiple-testing burden because of the need to test for associations with a vast number of single-nucleotide ...