Blar i Department of Global Public Health and Primary Care på tidsskrift "Clinical Epigenetics"

Viser treff 1-4 av 4

    • A comparison of DNA methylation in newborn blood samples from infants with and without orofacial clefts 

      Xu, Zongli; Lie, Rolv T.; Wilcox, Allen J.; Saugstad, Ola Didrik; Taylor, Jack A. (Peer reviewed; Journal article, 2019-03-04)
      Background Isolated orofacial clefts are among the most common congenital birth defects. Although the underlying biological mechanisms remain largely unknown, clefts are thought to be complex disorders influenced by genetic, ...

    • An EPIC predictor of gestational age and its application to newborns conceived by assisted reproductive technologies 

      Haftorn, Kristine Løkås; Lee, Yunsung; Denault, William Robert Paul; Page, Christian Magnus; Nustad, Haakon Egdetveit; Lyle, Robert; Gjessing, Håkon Kristian; Malmberg, Anni; Magnus, Maria Christine; Næss, Øyvind; Czamara, Darina; Räikkönen, Katri; Lahti, Jari; Magnus, Per Minor; Håberg, Siri Eldevik; Jugessur, Astanand; Bohlin, Jon (Journal article; Peer reviewed, 2021)
      Background: Gestational age is a useful proxy for assessing developmental maturity, but correct estimation of gestational age is difficult using clinical measures. DNA methylation at birth has proven to be an accurate ...

    • An examination of mediation by DNA methylation on birthweight differences induced by assisted reproductive technologies 

      Carlsen, Ellen Øen; Lee, Yunsung; Magnus, Per Minor; Jugessur, Astanand; Page, Christian Magnus; Nustad, Haakon Egdetveit; Håberg, Siri Eldevik; Lie, Rolv Terje; Magnus, Maria Christine (Journal article; Peer reviewed, 2022)
      Background Children born after assisted reproductive technologies (ART) differ in birthweight from those naturally conceived. It has been hypothesized that this might be explained by epigenetic mechanisms. We examined ...

    • Gene-methylation interactions: Discovering region-wise DNA methylation levels that modify SNP-associated disease risk 

      Romanowska, Julia; Haaland, Øystein Ariansen; Jugessur, Astanand; Gjerdevik, Miriam; Xu, Zongli; Taylor, Jack A.; Wilcox, Allen J; Jonassen, Inge; Lie, Rolv T.; Gjessing, Håkon K. (Journal article; Peer reviewed, 2020)
      Background Current technology allows rapid assessment of DNA sequences and methylation levels at a single-site resolution for hundreds of thousands of sites in the human genome, in thousands of individuals simultaneously. ...