Blar i Department of Clinical Dentistry på forfatter "Yassin, Mohammed Ahmed"
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Adenoviral mediated mono delivery of BMP2 is superior to the combined delivery of BMP2 and VEGFA in bone regeneration in a critical-sized rat calvarial bone defect
Sharma, Sunita; Xue, Ying; Xing, Zhe; Yassin, Mohammed Ahmed; Sun, Yang; Lorens, James; Finne-Wistrand, Anna; Sapkota, Dipak; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2019-04-11)Apart from osteogenesis, neovascularization of the defect area is an important determinant for successful bone healing. Accordingly, several studies have employed the combined delivery of VEGFA and BMP2 for bone regeneration. ... -
Cell seeding density is a critical determinant for copolymer scaffolds-induced bone regeneration
Yassin, Mohammed Ahmed; Leknes, Knut N.; Pedersen, Torbjørn Østvik; Xing, Zhe; Sun, Yang; Lie, Stein Atle; Finne-Wistrand, Anna; Mustafa, Kamal Babikeir Eln (Peer reviewed; Journal article, 2015-11)Constructs intended for bone tissue engineering (TE) are influenced by the initial cell seeding density. Therefore, the objective of this study was to determine the effect of bone marrow stromal stem cells (BMSCs) density ... -
Comparison of bone regenerative capacity of donor-matched human adipose–derived and bone marrow mesenchymal stem cells
Mohamed Ahmed, Samih; Yassin, Mohammed Ahmed; Elsebahy, Ahmad Rashad Saad Mohamed; Espedal, Heidi; Idris, Shaza Bushra M.; Finne-Wistrand, Anna; Vindenes, Hallvard; Mustafa, Kamal Babikeir Eln; Fristad, Inge (Journal article; Peer reviewed, 2020-11)Adipose-derived stem cells (ASC) have been used as an alternative to bone marrow mesenchymal stem cells (BMSC) for bone tissue engineering. However, the efficacy of ASC in bone regeneration in comparison with BMSC remains ... -
Computational and experimental characterization of 3D-printed PCL structures toward the design of soft biological tissue scaffolds
Liu, Hailong; Ahlinder, Astrid; Yassin, Mohammed Ahmed; Finne-Wistrand, Anna; Gasser, T. (Journal article; Peer reviewed, 2020)Degradable porous polymeric structures are attractive candidates for biological tissue scaffolds, and adequate mechanical, transport, chemical and biological properties determine their functionality. Aside from the properties ... -
Contact osteogenesis by biodegradable 3D-printed poly(lactide-co-trimethylene carbonate)
Hassan, Mohamad Nageeb Abdelaziz; Yassin, Mohammed Ahmed; Eltawila, Ahmed Maher; Aladawi, Ahmed Emad; Mohamed-Ahmed, Samih Salah Eldin Mahgoub; Suliman, Salwa; Kandil, Sherif; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2022)Background To support bone regeneration, 3D-printed templates function as temporary guides. The preferred materials are synthetic polymers, due to their ease of processing and biological inertness. Poly(lactide-co-trimethylene ... -
Engineering 3D degradable, pliable scaffolds toward adipose tissue regeneration; optimized printability, simulations and surface modification
Jain, Shubham; Yassin, Mohammed Ahmed; Fuoco, Tiziana; Liu, Hailong; Mohamed Ahmed, Samih; Mustafa, Kamal Babikeir Eln; Finne-Wistrand, Anna (Journal article; Peer reviewed, 2020)We present a solution to regenerate adipose tissue using degradable, soft, pliable 3D-printed scaffolds made of a medical-grade copolymer coated with polydopamine. The problem today is that while printing, the medical grade ... -
Induction of osteogenic differentiation of bone marrow stromal cells on 3D polyester-based scaffolds solely by subphysiological fluidic stimulation in a laminar flow bioreactor
Yamada, Shuntaro; Yassin, Mohammed Ahmed; Schwarz, Thomas; Hansmann, Jan; Mustafa, Kamal Babikeir Elnour (Journal article; Peer reviewed, 2021)The fatal determination of bone marrow mesenchymal stem/stromal cells (BMSC) is closely associated with mechano-environmental factors in addition to biochemical clues. The aim of this study was to induce osteogenesis in ... -
Surface activation with oxygen plasma promotes osteogenesis with enhanced extracellular matrix formation in three- dimensional microporous scaffolds
Yamada, Shuntaro; Yassin, Mohammed Ahmed; Weigel, Tobias; Schmitz, Tobias; Hansmann, Jan; Mustafa, Kamal Babikeir Eln (Journal article; Peer reviewed, 2021)Various types of synthetic polyesters have been developed as biomaterials for tissue engineering. These materials commonly possess biodegradability, biocompatibility, and formability, which are preferable properties for ... -
Unique osteogenic profile of bone marrow stem cells stimulated in perfusion bioreactor is Rho-ROCK-mediated contractility dependent
Yamada, Shuntaro; Yassin, Mohammed Ahmed; Torelli, Francesco; Hansmann, Jan; Green, Jeremy; Mustafa, Kamal (Journal article; Peer reviewed, 2023)The fate determination of bone marrow mesenchymal stem/stromal cells (BMSC) is tightly regulated by mechanical cues, including fluid shear stress. Knowledge of mechanobiology in 2D culture has allowed researchers in bone ...