• Deep conservation of ribosome stall sites across RNA processing genes 

      Chyzynska, Katarzyna; Labun, Kornel; Jones, Carl Matthew; Grellscheid, Sushma Nagaraja; Valen, Eivind Dale (Journal article; Peer reviewed, 2021)
      The rate of translation can vary depending on the mRNA template. During the elongation phase the ribosome can transiently pause or permanently stall. A pause can provide the nascent protein with the time to fold or be ...
    • ORFik: a comprehensive R toolkit for the analysis of translation 

      Tjeldnes, Håkon; Labun, Kornel; Torres Cleuren, Yamila Nicole; Chyzynska, Katarzyna; Swirski, Michal; Valen, Eivind Dale (Journal article; Peer reviewed, 2021)
      Background With the rapid growth in the use of high-throughput methods for characterizing translation and the continued expansion of multi-omics, there is a need for back-end functions and streamlined tools for processing, ...
    • Shoelaces: An interactive tool for ribosome profiling processing and visualization 

      Birkeland, Åsmund; Chyzynska, Katarzyna; Valen, Eivind (Peer reviewed; Journal article, 2018-07-18)
      Background: The emergence of ribosome profiling to map actively translating ribosomes has laid the foundation for a diverse range of studies on translational regulation. The data obtained with different variations of this ...