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Swabbing for respiratory viral infections in older patients: a comparison of rayon and nylon flocked swabs

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dc.contributor.author Hernes, Susanne
dc.contributor.author Quarsten, Hanne
dc.contributor.author Hagen, Egil
dc.contributor.author Lyngroth, Anne Liv
dc.contributor.author Pripp, Are Hugo
dc.contributor.author Bjorvatn, Bjarne
dc.contributor.author Bakke, Per S.
dc.date.accessioned 2011-03-04T13:54:19Z
dc.date.available 2011-03-04T13:54:19Z
dc.date.issued 2011
dc.identifier.citation European Journal of Clinical Microbiology & Infectious Diseases 30(2): 159-165 en_US
dc.identifier.issn 0934-9723
dc.identifier.uri http://dx.doi.org/10.1007/s10623-010-9469-6
dc.identifier.uri http://hdl.handle.net/1956/4549
dc.description.abstract The purpose of this study was to compare the sampling efficacy of rayon swabs and nylon flocked swabs, and of oropharyngeal and nasopharyngeal specimens for the detection of respiratory viruses in elderly patients. Samples were obtained from patients 60 years of age or above who were newly admitted to Sorlandet Hospital Arendal, Norway. The patients were interviewed for current symptoms of a respiratory tract infection. Using rayon swabs and nylon flocked swabs, comparable sets of mucosal samples were harvested from the nasopharynx and the oropharynx. The samples were analysed using real-time polymerase chain reaction (PCR) methods. A total of 223 patients (mean age 74.9 years, standard deviation [SD] 9.0 years) were swabbed and a virus was recovered from 11% of the symptomatic patients. Regardless of the sampling site, a calculated 4.8 times higher viral load (95% confidence interval [CI] 1.3–17, p = 0.017) was obtained using the nylon flocked swabs as compared to the rayon swabs. Also, regardless of the type of swab, a calculated 19 times higher viral load was found in the samples from the nasopharynx as compared to the oropharynx (95% CI 5.4–67.4, p < 0.001). When swabbing for respiratory viruses in elderly patients, nasopharyngeal rather than oropharyngeal samples should be obtained. Nylon flocked swabs appear to be more efficient than rayon swabs. en_US
dc.language.iso eng en_US
dc.publisher Springer en
dc.relation.ispartof <a href="http://hdl.handle.net/1956/7819" target="blank">Community acquired infections in adult and elderly airways; an evaluation of diagnostic harvesting techniques</a>
dc.rights Copyright The Author(s) 2010. This article is published with open access at Springerlink.com en_US
dc.rights.uri http://creativecommons.org/licenses/by-nc/2.5/ en_US
dc.title Swabbing for respiratory viral infections in older patients: a comparison of rayon and nylon flocked swabs en_US
dc.type Peer reviewed en_US
dc.type Journal article en_US
dc.subject.nsi VDP::Medical disciplines: 700 en_US
dc.rightsHolder The Author(s) 2010 en_US
dc.type.version publishedVersion en_US
bora.journalTitle European Journal of Clinical Microbiology & Infectious Diseases
bibo.volume 30
bibo.issue 2
bibo.pageStart 159
bibo.pageEnd 165
bora.cristinID 830324
bibo.doi http://dx.doi.org/10.1007/s10623-010-9469-6


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Copyright The Author(s) 2010. This article is published with open access at Springerlink.com Except where otherwise noted, this item's license is described as Copyright The Author(s) 2010. This article is published with open access at Springerlink.com

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