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An experimental study of low-level laser therapy in rat Achilles tendon injury

Bergen Open Research Archive

Show simple item record Joensen, Jon eng Gjerdet, Nils Roar eng Hummelsund, Steinar eng Iversen, Vegard Vereide eng Lopes-Martins, Rodrigo Álvaro Brandão eng Bjordal, Jan Magnus eng 2012-01-18T09:05:42Z 2012-01-18T09:05:42Z 2011-05-06 eng
dc.identifier.citation Lasers in Medical Science 27(1): 103-111 en
dc.identifier.issn 0268-8921 eng
dc.description.abstract The aim of this controlled animal study was to investigate the effect of low-level laser therapy (LLLT) administered 30 min after injury to the Achilles tendon. The study animals comprised 16 Sprague Dawley male rats divided in two groups. The right Achilles tendons were injured by blunt trauma using a mini guillotine, and were treated with LLLT or placebo LLLT 30 min later. The injury and LLLT procedures were then repeated 15 hours later on the same tendon. One group received active LLLT (1= 904 nm, 60 mW mean output power, 0.158 W/cm2 for 50 s, energy 3 J) and the other group received placebo LLLT 23 hours after LLLT. Ultrasonographic images were taken to measure the thickness of the right and left Achilles tendons. Animals were then killed, and all Achilles tendons were tested for ultimate tensile strength (UTS). All analyses were performed by blinded observers. There was a significant increase in tendon thickness in the active LLLT group when compared with the placebo group (p<0.05) and there were no significant differences between the placebo and uninjured left tendons. There were no significant differences in UTS between laser-treated, placebo-treated and uninjured tendons. Laser irradiation of the Achilles tendon at 0.158 W/cm2 for 50 s (3 J) administered within the first 30 min after blunt trauma, and repeated after 15 h, appears to lead to edema of the tendon measured 23 hours after LLLT. The guillotine blunt trauma model seems suitable for inflicting tendon injury and measuring the effects of treatment on edema by ultrasonography and UTS. More studies are needed to further refine this model. en
dc.language.iso eng eng
dc.publisher Springer eng
dc.relation.ispartof <a href="" target="blank">Biophysical and biological effects from infrared Low-Level-Laser-Therapy</a> eng
dc.rights Attribution-NonCommercial CC BY-NC eng
dc.rights.uri eng
dc.subject LLLT eng
dc.subject Ultrasonographic imaging eng
dc.subject Ultimate tensile strength eng
dc.title An experimental study of low-level laser therapy in rat Achilles tendon injury eng
dc.type Journal article eng
dc.type Peer reviewed eng
dc.subject.nsi VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Radiology and diagnostic imaging: 763 eng
dc.subject.nsi VDP::Medical disciplines: 700::Clinical medical disciplines: 750::Orthopedic surgery: 784 eng
dc.rights.holder Copyright The Author(s) 2011
dc.type.version publishedVersion eng
bora.peerreviewed Peer reviewed eng
bora.cristinID 869650 eng
bibo.doi eng
dc.identifier.cristinID 869650 eng

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