Browsing Department of Biological Sciences by Subject "CRISPR zebrafish MODY5 Diabetes"
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Gene-editing of the monogenic diabetes associated gene hnf1ba to model multisystemic MODY5 disease mechanisms in zebrafish (DR)
(Master thesis, 2021-12-03)Maturity-Onset Diabetes of the Young (MODY) is a rare form of monogenic diabetes, characterized by autosomal dominant inheritance, non-obesity, and early-onset diabetes due to reduced pancreatic beta-cell secretion. Precision ...