Blar i Department of Chemistry på forfatter "Camilio, Ketil Andre"
-
LTX-315: a first-in-class oncolytic peptide that reprograms the tumor microenvironment
Sveinbjørnsson, Baldur; Camilio, Ketil Andre; Haug, Bengt Erik; Rekdal, Øystein (Peer reviewed; Journal article, 2017)The oncolytic peptide LTX-315, which has been de novo designed based on structure–activity relationship studies of host defense peptides, has the ability to kill human cancer cells and induce specific anticancer immune ... -
Oncolytic peptide LTX-315 induces an immune-mediated abscopal effect in a rat sarcoma model
Nestvold, Janne M.; Wang, Mengyu; Camilio, Ketil Andre; Zinöcker, Severin; Tjelle, Torunn Elisabeth; Lindberg, Alf; Haug, Bengt Erik; Kvalheim, Gunnar; Sveinbjørnsson, Baldur; Rekdal, Øystein (Peer reviewed; Journal article, 2017)LTX 315 is an oncolytic peptide with potent immunological properties. In the present study, we demonstrate that intratumoral treatment with LTX-315 resulted in a complete regression and systemic immune response in a rat ...