Browsing Faculty of Medicine by Title
Now showing items 5634-5653 of 8830
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N-terminal acetylation of actin by NAA80 is essential for structural integrity of the Golgi apparatus
(Journal article; Peer reviewed, 2020)N-alpha-acetyltransferase 80 (NAA80) was recently demonstrated to acetylate the N-terminus of actin, with NAA80 knockout cells showing actin cytoskeleton-related phenotypes, such as increased formation of membrane protrusions ... -
N-terminal pro-B-type natriuretic peptide as a prognostic indicator for 30-day mortality following out-of-hospital cardiac arrest: A prospective observational study
(Journal article; Peer reviewed, 2020-08-24)Background Early risk stratification applying cardiac biomarkers may prove useful in sudden cardiac arrest patients. We investigated the prognostic utility of early-on levels of high sensitivity cardiac troponin-T (hs-cTnT), ... -
N-terminal pro-B-type natriuretic peptide for prediction of ventricular arrhythmias: Data from the SMASH study
(Journal article; Peer reviewed, 2023)Background Elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations predict heart failure (HF) and mortality, but whether NT-proBNP predicts ventricular arrhythmias (VA) is not clear. Hypothesis We ... -
N-terminal pro-B-type natriuretic peptide level at longterm follow-up after atrial fibrillation ablation: A marker of reverse atrial remodeling and successful ablation
(Peer reviewed; Journal article, 2011-10-13)Aims: We investigated the relationship between arrhythmia burden, left atrial volume (LAV) and N-terminal pro-B-type natriuretic peptide (NT-pro-BNP) at baseline and after long-term follow-up of atrial fibrillation (AF) ... -
The N-terminal sequence of tyrosine hydroxylase is a conformationally versatile motif that binds 14-3-3 proteins and membranes
(Peer reviewed; Journal article, 2014-01-09)Tyrosine hydroxylase (TH) catalyzes the rate-limiting step in the synthesis of catecholamine neurotransmitters, and a reduction in TH activity is associated with several neurological diseases. Human TH is regulated, among ... -
Na+ is shifted from the extracellular to the intracellular compartment and is not inactivated by glycosaminoglycans during high salt conditions in rats
(Journal article; Peer reviewed, 2022)Recently, studies have emerged suggesting that the skin plays a role as major Na+ reservoir via regulation of the content of glycosaminoglycans and osmotic gradients. We investigated whether there were electrolyte gradients ... -
NAA10 p.(D10G) and NAA10 p.(L11R) variants hamper formation of the NatA N-terminal acetyltransferase complex
(Journal article; Peer reviewed, 2020)The majority of the human proteome is subjected to N-terminal (Nt) acetylation catalysed by N-terminal acetyltransferases (NATs). The NatA complex is composed of two core subunits—the catalytic subunit NAA10 and the ribosomal ... -
NAA10 p.(N101K) disrupts N-terminal acetyltransferase complex NatA and is associated with developmental delay and hemihypertrophy
(Journal article; Peer reviewed, 2020)Nearly half of all human proteins are acetylated at their N-termini by the NatA N-terminal acetyltransferase complex. NAA10 is evolutionarily conserved as the catalytic subunit of NatA in complex with NAA15, but may also ... -
The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson’s disease
(Journal article; Peer reviewed, 2022)We conducted a double-blinded phase I clinical trial to establish whether nicotinamide adenine dinucleotide (NAD) replenishment therapy, via oral intake of nicotinamide riboside (NR), is safe, augments cerebral NAD levels, ... -
Nakkens betydning for postural kontroll
(Master thesis, 2012-11-01)Background: Neck disorders may affect as many as 70% of the general population at some point. Neck disorders are multidimensional, and are assumed to affect postural control. Manual therapists often see patients with neck ... -
Nano-TiO2 penetration of oral mucosa: in vitro analysis using 3D organotypic human buccal mucosa models
(Peer reviewed; Journal article, 2016)BACKGROUND: Oral cavity is a doorway for a variety of products containing titanium dioxide (TiO2) nanoparticles (NPs) (nano-TiO2) such as food additives, oral healthcare products and dental materials. Their potential to ... -
Nanodiamond modified copolymer scaffolds affects tumour progression of early neoplastic oral keratinocytes
(Peer reviewed; Journal article, 2016-07)This study aimed to evaluate the tumorigenic potential of functionalising poly(LLA-co-CL) scaffolds. The copolymer scaffolds were functionalised with nanodiamonds (nDP) or with nDP and physisorbed BMP-2 (nDP-PHY) to enhance ... -
Nanosafety aspects: Dental health care workers’ perception of nanomaterials and in vitro nanotoxicity assessment using new approach methodologies
(Doctoral thesis, 2024-05-23)Nanoteknologi er i utstrakt bruk innen sektorer som medisin og odontologi, forbrukerprodukter, energi og landbruk. Toksiske effekter knyttet til bruk av nanomaterialer (NM) og nanopartikler (NP) har vekket bekymring på ... -
Narcolepsy and hypersomnia in Norwegian children and young adults following the influenza A(H1N1) 2009 pandemic
(Peer reviewed; Journal article, 2017-04)Background: Associations between influenza infection and sleep disorders are poorly studied. We investigated if pandemic influenza infection or vaccination with Pandemrix in 2009/2010 was associated with narcolepsy or ... -
Narrative Approach for Identifying Movements of Change and the Value of Therapeutic Writing Related to Chronic pain Management
(Peer reviewed; Journal article, 2016)In this study, we examined extensive narratives prepared by participants who attended a chronic pain management programme where therapeutic writing was included. The aim was to explore how narrators experience the contexts ... -
A narrative approach to explore grief experiences and treatment adherence in people with chronic pain after participation in a pain-management program: a 6-year follow-up study
(Peer reviewed; Journal article, 2013-08-09)Objective: The aim of this study was to explore grief caused by chronic pain and treatment adherence, and how these experiences are integrated into ongoing life stories. Methods: A 6-year follow-up using a qualitative ... -
A Narrative of Oral Care in Palliative Patients
(Journal article; Peer reviewed, 2022)Painful oral conditions represent a significant problem for most patients with a serious disease and palliative care needs. The main causes of such conditions may be associated with the underlying disease and its treatment, ... -
Nasal symptoms increase the risk of snoring and snoring increases the risk of nasal symptoms. A longitudinal population study
(Journal article; Peer reviewed, 2021)Purpose Humans have a preference for nasal breathing during sleep. This 10-year prospective study aimed to determine if nasal symptoms can predict snoring and also if snoring can predict development of nasal symptoms. The ... -
Nasjonale registerkilder i epidemiologisk forskning
(Peer reviewed; Journal article, 2017)