Blar i Faculty of Medicine på tittel
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Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen
(Journal article; Peer reviewed, 2021)Low steady‐state levels of active tamoxifen metabolites have been associated with inferior treatment outcomes. In this retrospective analysis of 406 estrogen receptor‐positive breast cancer (BC) patients receiving adjuvant ... -
Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism
(Peer reviewed; Journal article, 2016-12-04)The underlying mechanisms responsible for the development of castration-resistant prostate cancer (CRPC) in patients who have undergone androgen deprivation therapy are not fully understood. This is the first study to ... -
Low-energy fracture of the distal radius in middleaged and elderly Norwegian women and men. Topics related to osteoporosis, fracture risk and vitamin D
(Doctoral thesis, 2011-02-25)Introduction: Low-energy distal radius fractures normally occur earlier in life than hip and spine fractures and may be the first presentation of osteoporosis. Few studies have addressed the association between distal ... -
Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells
(Journal article; Peer reviewed, 2020)The use of ultrasound (US) and microbubbles (MB), usually referred to as sonoporation, has great potential to increase the efficacy of chemotherapy. However, the molecular mechanisms that mediate sonoporation response are ... -
Low-Level Laser Therapy and Cryotherapy in Tendinopathy Treatment. Clinical, biological, and biophysical effects of low-level laser therapy alone and in combination with cryotherapy
(Doctoral thesis, 2018-06-12)Introduction: Low-level laser therapy (LLLT) and cryotherapy are applied to the human skin to trigger biological actions in the underlying tissue. LLLT modulates biological processes by emitting energy-charged photons to ... -
The lower airway microbiota and inflammation in chronic obstructive pulmonary disease (COPD) : Thoughts on where to measure it, how to interpret it, and why it might matter
(Doctoral thesis, 2024-02-01)Bakgrunn: Kronisk obstruktiv lungesjukdom (KOLS) er ein kompleks, inflammatorisk sjukdom som forårsakar millionar av dødsfall årleg. Bakteriane i dei nedre luftvegane (mikrobiotaet) og immunresponsar kan spele ei viktig ... -
The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease
(Journal article; Peer reviewed, 2022)Background The lower airways microbiome and host immune response in chronic pulmonary diseases are incompletely understood. We aimed to investigate possible microbiome characteristics and key antimicrobial peptides and ... -
The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis
(Journal article; Peer reviewed, 2022-10-19)Background: The role of the pulmonary microbiome in sarcoidosis is unknown. The objectives of this study were the following: (1) examine whether the pulmonary fungal and bacterial microbiota differed in patients with ... -
Lower antibiotic prescription rates in hospitalized COVID-19 patients than influenza patients, a prospective study
(Journal article; Peer reviewed, 2022)Background COVID-19 patients are extensively treated with antibiotics despite few bacterial complications. We aimed to study antibiotic use in hospitalized COVID-19 patients compared to influenza patients in two consecutive ... -
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
(Journal article; Peer reviewed, 2021)Background: Both neurodegenerative and neurodevelopmental abnormalities have been suggested to be part of the etiopathology of severe mental illness (SMI). Neuron-specific enolase (NSE), mainly located in the neuronal ... -
Lower conversion rate with robotic assisted rectal resections compared with conventional laparoscopy; a national cohort study
(Journal article; Peer reviewed, 2021)Background Conversion from laparoscopic to open access colorectal surgery is associated with a poorer postoperative outcome. The aim of this study was to assess conversion rates and outcomes after standard laparoscopic ... -
Lower education and immigrant background are associated with lower participation in a diabetes education program - Insights from adult patients in the Outcomes & Multi-morbidity In Type 2 diabetes cohort (OMIT)
(Journal article; Peer reviewed, 2023)Objectives Diabetes educational programmes should be offered to patients with type 2 diabetes mellitus (T2DM). We assessed the proportion of diabetes educational program participation among adults with T2DM, and its ... -
Lower extremity neuromuscular deficits associated with obstetric fistula
(Master thesis, 2011)SUMMARY Background: Obstetric fistula affects thousands of women every year, one of the dreadful consequences of surviving an obstructed labour. A majority of these are left untreated, abandoned by their husband and family ... -
Lower risk of smoking-related cancer in individuals with familial hypercholesterolemia compared with controls: a prospective matched cohort study
(Peer reviewed; Journal article, 2019-12-17)According to guidelines, individuals with familial hypercholesterolemia (FH) shall receive lifestyle intervention and intensive lipid-lowering treatment from early in life to reduce the risk of coronary heart disease. Our ... -
Lower secondary school students’ scientific literacy and their proficiency in identifying and appraising health claims in news media: a secondary analysis using large-scale survey data
(Peer reviewed; Journal article, 2019-10-18)Objectives: Scientific literacy is assumed necessary for appraising the reliability of health claims. Using a national science achievement test, we explored whether students located at the lower quartile on the latent trait ... -
Lowering of tumor interstitial fluid pressure reduces tumor cell proliferation in a xenograft tumor model
(Peer reviewed; Journal article, 2006-02)High tumor interstitial fluid pressure (TIFP) is a characteristic of most solid tumors. TIFP may hamper adequate uptake of macromolecular therapeutics in tumor tissue. In addition, TIFP generates mechanical forces affecting ... -
LPS quantification of oral samples from the RHINESSA study population
(Master thesis, 2023-06-01)The human immune system defends the body against threats through a complex network of organs, cells, and proteins. It has two subsystems: the innate immune system provides immediate defense, while the adaptive immune system ... -
LRFN5 locus structure is associated with autism and influenced by the sex of the individual and locus conversions
(Journal article; Peer reviewed, 2022)LRFN5 is a regulator of synaptic development and the only gene in a 5.4 Mb mammalian-specific conserved topologically associating domain (TAD); the LRFN5 locus. An association between locus structural changes and developmental ... -
LTP mechanisms in the dentate gyrus in vivo: BDNF signaling, translation control, and gene function
(Doctoral thesis, 2007-03-30) -
The lucky ones get cured: Health care seeking among women with pelvic organ prolapse in Amhara Region, Ethiopia
(Peer reviewed; Journal article, 2018-11-26)Background: The majority of women suffering from maternal morbidities live in resource-constrained settings with diverse barriers preventing access to quality biomedical health care services. This study aims to highlight ...