Blar i Faculty of Medicine på tittel

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    • Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjogren's syndrome in salivary glands of non-obese diabetic mice 

      Gatumu, Margaret Karimi; Skarstein, Kathrine; Papandile, Adrian; Browning, Jeffrey L.; Fava, Roy A.; Bolstad, Anne Isine (Peer reviewed; Journal article, 2009-02-18)
      Introduction The lymphotoxin-beta receptor (LTβR) pathway is important in the development and maintenance of lymphoid structures. Blocking this pathway has proven beneficial in murine models of autoimmune diseases such as ...

    • Blood eosinophils during bronchiolitis: Associations with atopy, asthma and lung function in young adults 

      Sørensen, Karen Galta; Øymar, Knut Asbjørn Alexander; Dalen, Ingvild; Halvorsen, Thomas; Mikalsen, Ingvild Bruun (Journal article; Peer reviewed, 2023)
      Aim: To study if blood eosinophils during bronchiolitis were associated with atopy, asthma and lung function in young adults and if these associations differed between respiratory syncytial virus (RSV) bronchiolitis and ...

    • Blood glucose and risk of incident and fatal cancer in the metabolic syndrome and cancer project (me-can): analysis of six prospective cohorts 

      Stocks, Tanja; Rapp, Kilian; Bjørge, Tone; Manjer, Jonas; Ulmer, Hanno; Selmer, Randi Marie; Lukanova, Annekatrin; Johansen, Dorthe; Concin, Hans; Tretli, Steinar; Hallmans, Göran; Jonsson, Håkan; Stattin, Pär (Peer reviewed; Journal article, 2009-12-22)
      Background: Prospective studies have indicated that elevated blood glucose levels may be linked with increased cancer risk, but the strength of the association is unclear. We examined the association between blood glucose ...

    • Blood Lactate AUC Is a Sensitive Test for Evaluating the Effect of Exercise Training on Functional Work Capacity in Patients with Chronic Heart Failure 

      Valborgland, Torstein; Isaksen, Kjetil; Munk, Peter Scott; Larsen, Alf Inge (Journal article; Peer reviewed, 2021)
      Purpose. Exercise training is an essential treatment option for patients with chronic heart failure (CHF). However, it remains controversial, which surrogate measures of functional work capacity are most reliable. The ...

    • Blood meal origins and insecticide susceptibility of Anopheles arabiensis from Chano in South-West Ethiopia 

      Ulesido, Fekadu Massebo; Balkew, Meshesha; Gebre-Michael, Teshome; Lindtjørn, Bernt (Peer reviewed; Journal article, 2013-02-22)
      Background: Anopheles arabiensis, the main malaria vector in Ethiopia, shows both anthropophilic and zoophilic behaviours. Insecticide resistance is increasing, and alternative methods of vector control are needed. The ...

    • Blood meal sources and entomological inoculation rates of anophelines along a highland altitudinal transect in south-central Ethiopia 

      Ayele, Abebe Animut; Balkew, Meshesha; Gebre-Michael, Teshome; Lindtjørn, Bernt (Peer reviewed; Journal article, 2013-02-23)
      Background: The role of anophelines in transmitting malaria depends on their distribution, preference to feed on humans and also their susceptibility to Plasmodium gametocytes, all of which are affected by local environmental ...

    • Blood Metabolites Associate with Prognosis in Endometrial Cancer 

      Strand, Elin; Tangen, Ingvild Løberg; Fasmer, Kristine Eldevik; Jacob, Havjin; Halle, Mari Kyllesø; Hoivik, Erling A; Delvoux, Bert; Trovik, Jone; Haldorsen, Ingfrid S.; Romano, Andrea; Krakstad, Camilla (Peer reviewed; Journal article, 2019-12-14)
      Endometrial cancer has a high prevalence among post-menopausal women in developed countries. We aimed to explore whether certain metabolic patterns could be related to the characteristics of aggressive disease and poorer ...

    • Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID‑19 

      Aamodt, Anne Hege; Høgestøl, Einar August; Popperud, Trine Haug; Holter, Jan Cato; Dyrhol-Riise, Anne Ma; Tonby, Kristian; Stiksrud, Birgitte; Berge, Tone; Barratt-Due, Andreas; Aukrust, Pål; Heggelund, Lars; Blennow, Kaj; Zetterberg, Henrik; Harbo, Hanne Flinstad; Quist‑Paulsen, Else (Journal article; Peer reviewed, 2021)
      Objective To test the hypotheses that blood biomarkers for nervous system injury, serum concentrations of neurofilament light chain protein (NfL) and glial fibrillary acidic protein (GFAp) can serve as biomarkers for ...

    • Blood Pressure Treatment in Kidney Transplant Recipients—Can We Improve? 

      Onsøien, Mari Olsen; Midtvedt, Karsten; Reisæter, Anna Varberg; Aasarød, Knut; Waldum-Grevbo, Bård; Vikse, Bjørn Egil; Eriksen, Bjørn Odvar; Åsberg, Anders (Journal article; Peer reviewed, 2021)
      Background. Hypertension in kidney transplant (KTx) recipients is common, affecting both patient and graft survival. Annual data from the Norwegian Renal Registry reveal that <50% of adult (>18 y) KTx recipients reach ...

    • Blood pressure, antihypertensive medication and neuropsychiatric symptoms in older people with dementia: The COSMOS study 

      de Jong-Schmit, Bianca E. M.; Poortvliet, Rosalinde K. E.; Böhringer, Stefan; Bogaerts, Jonathan M. K.; Achterberg, Wilco P.; Husebø, Bettina (Journal article; Peer reviewed, 2021)
      Objectives Neuropsychiatric symptoms (NPS) are very common in older patients with dementia. There is increasing evidence that hypoperfusion of the brain plays a role in the development of NPS. The aim of this study is to ...

    • Blood steroid levels predict survival in endometrial cancer and reflect tumor estrogen signaling 

      Forsse, David Erik; Tangen, Ingvild Løberg; Fasmer, Kristine Eldevik; Halle, Mari Kyllesø; Viste, Kristin; Almås, Bjørg; Bertelsen, Bjørn-Erik; Trovik, Jone; Haldorsen, Ingfrid S.; Krakstad, Camilla (Peer reviewed; Journal article, 2020-02)
      Objective Blood-based biomarkers are attractive due to ease of sampling and standardized measurement technology, reducing obstacles to clinical implementation. The objective of this study was to evaluate a clinically ...

    • Blood-based epigenetic estimators of chronological age in human adults using DNA methylation data from the Illumina MethylationEPIC array 

      Lee, Yunsung; Løkås Haftorn, Kristine; Denault, William Robert Paul; Nustad, Haakon Egdetveit; Page, Christian; Moen, Gunn-Helen; Magnus, Maria C.; Gjessing, Håkon K.; Harris, Jennifer R.; Magnus, Per; Håberg, Siri E.; Jugessur, Astanand; Bohlin, Jon; Lyle, Robert; Lee-Ødegård, Sindre; Groop, Leif C.; Prasad, Rashmi B.; Sletner, Line; Sommer, Christine (Journal article; Peer reviewed, 2020)
      Background Epigenetic clocks have been recognized for their precise prediction of chronological age, age-related diseases, and all-cause mortality. Existing epigenetic clocks are based on CpGs from the Illumina ...

    • Bloodlettings in Hemochromatosis Result in Increased Blood Lead (Pb) Concentrations 

      Yazdani, Mazyar; Distante, Sonia; Mørkrid, Lars; Ulvik, Rune Johan; Bolann, Bjørn Johan (Journal article; Peer reviewed, 2022)
      Hemochromatosis is a hereditary disorder, most often associated with mutations of the HFE (High FErrum) gene. If left untreated, it can result in severe parenchymal iron accumulation. Bloodletting is the mainstay treatment. ...

    • BLR1 and FCGR1A transcripts in peripheral blood associate with the extent of intrathoracic tuberculosis in children and predict treatment outcome 

      Jenum, Synne; Bakken, Rasmus; Sivakumaran, Dhanasekaran; Mukherjee, Aparna; Lodha, Rakesh; Singh, Sarman; Singh, Varinder; Haks, Marielle C.; Ottenhoff, Tom H.M.; Kabra, Sushil K.; Doherty, Timothy Mark; Ritz, Christian; Grewal, Harleen (Peer reviewed; Journal article, 2016-12-12)
      Biomarkers reflecting the extent of Mycobacterium tuberculosis-induced pathology and normalization during anti-tuberculosis treatment (ATT) would considerably facilitate trials of new treatment regimens and the identification ...

    • Blue-blocking glasses as additive treatment for mania: A randomized placebo-controlled trial 

      Henriksen, Tone Elise Gjøtterud; Skrede, Silje; Fasmer, Ole Bernt; Schøyen, Helle Kristine; Leskauskaite, Ieva; Bjørke-Bertheussen, Janette; Assmus, Jörg; Hamre, Børge; Grønli, Janne; Lund, Anders (Peer reviewed; Journal article, 2016-05)
      Objectives: The discovery of the blue lightsensitive retinal photoreceptor responsible for signaling daytime to the brain suggested that light to the circadian system could be inhibited by using blue-blocking orange tinted ...

    • Blue-blocking glasses as adjunctive treatment for bipolar mania - and exploration of motor activity patterns in serious mental disorders 

      Henriksen, Tone Elise Gjøtterud (Doctoral thesis, 2020-10-23)
      Background: There is a need for more effective treatments of bipolar mania. Promising reports of the effects of dark therapy on bipolar disorder symptoms and the discovery of a mainly blue-light sensitive daylight-signaling ...

    • BMI and BMI SDS in childhood: annual increments and conditional change 

      Brannsether-Ellingsen, Bente; Eide, Geir Egil; Roelants, Mathieu; Bjerknes, Robert; Juliusson, Petur Benedikt (Peer reviewed; Journal article, 2016)
      Background: Early detection of abnormal weight gain in childhood may be important for preventive purposes. It is still debated which annual changes in BMI should warrant attention. Aim: To analyse 1-year increments of Body ...

    • Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study 

      Hughes, Amanda M.; Sanderson, Eleanor; Morris, Tim; Ayorech, Ziada; Tesli, Martin Steen; Ask, Helga; Reichborn-Kjennerud, Ted; Andreassen, Ole; Magnus, Per Minor; Helgeland, Øyvind; Johansson, Stefan; Njølstad, Pål Rasmus; Davey Smith, George; Havdahl, Alexandra Karoline Saasen; Howe, Laura D.; Davies, Neil Martin (Journal article; Peer reviewed, 2022)
      Background: Higher BMI in childhood is associated with emotional and behavioural problems, but these associations may not be causal. Results of previous genetic studies imply causal effects but may reflect influence of ...

    • Body mass index and physical activity in early childhood are associated with atopic sensitization, atopic dermatitis and asthma in later childhood 

      Øymar, Knut; Byberg, Kristine Kjer; Eide, Geir Egil; Forman, Michele R.; Júlíusson, Pétur Benedikt (Peer reviewed; Journal article, 2016-08-24)
      Background: The results of studies on the associations of childhood excessive weight/obesity and physical activity with atopic sensitization and atopic diseases are inconsistent. We studied the associations of anthropometry ...

    • Body mass index and weight change are associated with adult lung function trajectories: the prospective ECRHS study 

      Peralta, Gabriela P.; Marcon, Alessandro; Carsin, Anne-Elie; Abramson, Michael J.; Accordini, Simone; Amaral, André F.S.; Antó, Josep Maria; Bowatte, Gayan; Burney, Peter; Corsico, Angelo; Demoly, Pascal; Dharmage, Shyamali C.; Forsberg, Bertil; Fuertes, Elaine; Garcia-Larsen, Vanessa; Gislason, Thorarinn; Gullón, José-Antonio; Heinrich, Joachim; Holm, Mathias; Jarvis, Deborah; Janson, Christer; Jõgi, Rain; Johannessen, Ane; Leynaert, Bénédicte; Rovira, Jesús Martínez-Moratalla; Nowak, Dennis; Probst-Hensch, Nicole; Raherison, Chantal; Sánchez-Ramos, José Luis; Sigsgaard, Torben; Siroux, Valérie; Squillacioti, Giulia; Urrutia, Isabel; Weyler, Joost; Zock, Jan-Paul; Garcia-Aymerich, Judith (Journal article; Peer reviewed, 2020)
      Background Previous studies have reported an association between weight increase and excess lung function decline in young adults followed for short periods. We aimed to estimate lung function trajectories during adulthood ...