Blar i Faculty of Medicine på forfatter "Fasmer, Ole Bernt"
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Does changing from a first generation antipsychotic (perphenazin) to a second generation antipsychotic (risperidone) alter brain activation and motor activity? A case report
Berle, Jan Øystein; Løberg, Else-Marie; Fasmer, Ole Bernt (Peer reviewed; Journal article, 2013-05-06)Background: In patients with schizophrenia, altered brain activation and motor activity levels are central features, reflecting cognitive impairments and negative symptoms, respectively. Newer studies using nonlinear methods ... -
Genome wide association study identifies variants in NBEA associated with migraine in bipolar disorder
Jacobsen, Kaya Kvarme; Nievergelt, Caroline M.; Zayats, Tetyana; Greenwood, Tifany A.; Anttila, Verneri; Akiskal, Hagop Souren; Haavik, Jan; Fasmer, Ole Bernt; Kelsoe, John R.; Johansson, Stefan; Ødegaard, Ketil Joachim (Peer reviewed; Journal article, 2015-10-12)Background. Migraine is a common comorbidity among individuals with bipolar disorder, but the underlying mechanisms for this co-occurrence are poorly understood. The aim of this study was to investigate the genetic background ... -
HYPERAKTIV: An Activity Dataset from Patients with Attention-Deficit/Hyperactivity Disorder (ADHD)
Hicks, Steven; Stautland, Andrea; Fasmer, Ole Bernt; Førland, Wenche; Hammer, Hugo Lewi; Halvorsen, Pål; Mjeldheim, Kristin; Ødegaard, Ketil Joachim; Osnes, Berge; Syrstad, Vigdis Elin Giæver; Riegler, Michael; Jakobsen, Petter (Chapter, 2021)Machine learning research within healthcare frequently lacks the public data needed to be fully reproducible and comparable. Datasets are often restricted due to privacy concerns and legal requirements that come with ... -
Individual Variability in Reaction Time and Prediction of Clinical Response to Methylphenidate in Adult ADHD: A Prospective Open Label Study Using Conners’ Continuous Performance Test II
Fredriksen, Mats; Egeland, Jens; Haavik, Jan; Fasmer, Ole Bernt (Peer reviewed; Journal article, 2019)Objective: The aim of this study was to examine whether reaction time parameters in adult patients with ADHD could predict their response to methylphenidate (MPH). Method: Previously unmedicated patients (N = 123) were ... -
Innovative approaches in investigating inter-beat intervals: Graph theoretical method suggests altered autonomic functioning in adolescents with ADHD
Kvadsheim, Elisabet; Fasmer, Ole Bernt; Fasmer, Erlend Eindride; Hauge, Erik Rønneberg; Thayer, Julian F.; Osnes, Berge; Haavik, Jan; Koenig, Julian; Adolfsdottir, Steinunn; Plessen, Kerstin J.; Sørensen, Lin (Journal article; Peer reviewed, 2022)Cardiac inter-beat intervals (IBIs) are considered to reflect autonomic functioning and self-regulatory abilities and are often investigated by traditional time- and frequency domain analyses. These analyses investigate ... -
Linear and non-linear analyses of Conner’s Continuous Performance Test-II discriminate adult patients with attention deficit hyperactivity disorder from patients with mood and anxiety disorders
Fasmer, Ole Bernt; Mjeldheim, Kristin; Førland, Wenche; Hansen, Anita Lill; Syrstad, Vigdis Elin Giæver; Ødegaard, Ketil Joachim; Berle, Jan Øystein (Peer reviewed; Journal article, 2016-08-11)Background: Attention Deficit Hyperactivity Disorder (ADHD) is a heterogeneous disorder. Therefore it is important to look for factors that can contribute to better diagnosis and classification of these patients. The aims ... -
Motor activity patterns in acute schizophrenia and other psychotic disorders can be differentiated from bipolar mania and unipolar depression
Krane-Gartiser, Karoline; Henriksen, Tone Elise Gjøtterud; Morken, Gunnar; Vaaler, Arne; Fasmer, Ole Bernt (Peer reviewed; Journal article, 2018-12)The purpose of this study was to compare 24-h motor activity patterns between and within three groups of acutely admitted inpatients with schizophrenia and psychotic disorders (n = 28), bipolar mania (n = 18) and motor-retarded ... -
A Naturalistic Study of the Effect of Acupuncture on Heart-Rate Variability
Fasmer, Ole Bernt; Liao, Hanbo; Huang, Yong; Berle, Jan Øystein; Wu, Junxian; Ødegaard, Ketil Joachim; Wik, Gustav; Zhang, Zhangjin (Peer reviewed; Journal article, 2012-02)Objectives: To study the effect of acupuncture on heart rate variability (HRV) by using linear and non-linear methods of analysis. Methods: 40 patients were recruited consecutively, including patients with insomnia, ... -
Nonlinear Analysis of Motor Activity Shows Differences between Schizophrenia and Depression: A Study Using Fourier Analysis and Sample Entropy
Hauge, Erik R.; Berle, Jan Øystein; Ødegaard, Ketil Joachim; Holsten, Fred; Fasmer, Ole Bernt (Peer reviewed; Journal article, 2011-01-28)The purpose of this study has been to describe motor activity data obtained by using wrist-worn actigraphs in patients with schizophrenia and major depression by the use of linear and non-linear methods of analysis. Different ... -
Objective assessment of motor activity in a clinical sample of adults with attention-deficit/hyperactivity disorder and/or cyclothymic temperament
Syrstad, Vigdis Elin Giæver; Mjeldheim, Kristin; Førland, Wenche; Jakobsen, Petter; Gjestad, Rolf; Berle, Jan Øystein; Merikangas, Kathleen Ries; Ødegaard, Ketil Joachim; Fasmer, Ole Bernt (Journal article; Peer reviewed, 2022)Background Most research on patterns of motor activity has been conducted on adults with mood disorders, but few studies have investigated comorbid attention-deficit/hyperactivity disorder (ADHD) or temperamental factors ... -
Observed communication skills: how do they relate to the consultation content? A nation-wide study of graduate medical students seeing a standardized patient for a first-time consultation in a general practice setting
Gude, Tore; Vaglum, Per; Anvik, Tor; Bærheim, Anders; Eide, Hilde; Fasmer, Ole Bernt; Graugaard, Peter; Grimstad, Hilde; Hjortdahl, Per; Holen, Are; Nordoy, Tone; Skirbekk, Helge; Finset, Arnstein (Peer reviewed; Journal article, 2007-11-08)Background In this study, we wanted to investigate the relationship between background variables, communication skills, and the bio-psychosocial content of a medical consultation in a general practice setting with a ... -
Patterns of motor activity in spontaneously hypertensive rats compared to Wistar Kyoto rats
Fasmer, Ole Bernt; Johansen, Espen Borgå (Peer reviewed; Journal article, 2016-12-01)Background: Increased motor activity is a defining characteristic of patients with ADHD, and spontaneously hypertensive rats have been suggested to be an animal model of this disorder. In the present study, we wanted to ... -
A pilot study to determine whether combinations of objectively measured activity parameters can be used to differentiate between mixed states, mania, and bipolar depression
Scott, Janine Linda; Vaaler, Arne; Fasmer, Ole Bernt; Morken, Gunnar; Krane-Gartiser, Karoline (Peer reviewed; Journal article, 2017-03-01)Background: Until recently, actigraphy studies in bipolar disorders focused on sleep rather than daytime activity in mania or depression, and have failed to analyse mixed episodes separately. Furthermore, even those studies ... -
Reduced heart rate variability during mania in a repeated naturalistic observational study
Stautland, Andrea; Jakobsen, Petter; Fasmer, Ole Bernt; Osnes, Berge; Tørresen, Jim; Nordgreen, Tine; Ødegaard, Ketil Joachim (Journal article; Peer reviewed, 2023)Background: Bipolar disorder (BD) is a chronic recurrent mood disorder associated with autonomic nervous system (ANS) dysfunction, indexed by heart rate variability (HRV). Changes in HRV between mood states are sparsely ... -
Vagally mediated heart rate variability, stress, and perceived social support: a focus on sex differences
Kvadsheim, Elisabet; Sørensen, Lin; Fasmer, Ole Bernt; Osnes, Berge; Haavik, Jan; Williams, DeWayne P.; Thayer, Julian Francis; Koenig, Julian (Journal article; Peer reviewed, 2022)Higher vagally mediated heart rate variability (vmHRV), reflecting vagal activity as indexed by heart function and lower stress vulnerability, is associated with higher perceived social support. Seeking social support is ... -
Variability of activity patterns across mood disorders and time of day
Krane-Gartiser, Karoline; Vaaler, Arne; Fasmer, Ole Bernt; Sørensen, Kjetil; Morken, Gunnar; Scott, Janine Linda (Peer reviewed; Journal article, 2017-12-19)Background: Few actigraphy studies in mood disorders have simultaneously included unipolar (UP) and bipolar (BD) depression or BD mixed states as a separate subgroup from mania. This study compared objectively measured ...