Blar i Faculty of Medicine på tittel

Viser treff 3626-3645 av 8833

    • Guideline-Recommended Time Less Than 90 Minutes From ECG to Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Myocardial Infarction Is Associated with Major Survival Benefits, Especially in Octogenarians: A Contemporary Report in 11 226 Patients from NORIC 

      Larsen, Alf Inge; Løland, Kjetil Halvorsen; Hovland, Siren; Bleie, Øyvind; Eek, Christian; Fossum, Eigil; Trovik, Thor; Juliebø, Vibeke; Hegbom, Knut; Moer, Rasmus; Larsen, Tomas; Uchto, Michael; Rotevatn, Svein (Journal article; Peer reviewed, 2022)
      Background Using contemporary data from NORIC (Norwegian Registry of Invasive Cardiology) we investigated the predictive value of patient age and time from ECG diagnosis to sheath insertion (ECG‐2‐sheath) in primary ...

    • Guidelines and clinical priority setting during the COVID-19 pandemic – Norwegian doctors’ experiences 

      Bringedal, Berit; Isaksson Rø, Karin Elisabet; Bååthe, Fredrik; Miljeteig, Ingrid; Magelssen, Morten (Journal article; Peer reviewed, 2022)
      Background In the first phase of the COVID-19 pandemic, strong measures were taken to avoid anticipated pressure on health care, and this involved new priorities between patient groups and changing working conditions for ...

    • Gut microbiota and fecal microbiota transplantation in patients with food allergies: A systematic review 

      Jensen, Caroline; Antonsen, Marie Fagervik; Lied, Gülen Arslan (Journal article; Peer reviewed, 2022-09-26)
      The prevalence of food allergies (FAs) has increased considerably in recent decades, with the only available treatment being the avoidance of the specific food items causing the allergy. FAs may have a major impact on ...

    • Gut microbiota and therapeutic approaches for dysbiosis in irritable bowel syndrome: recent developments and future perspectives 

      Dale, Hanna Fjeldheim; Lied, Gülen Arslan (Journal article; Peer reviewed, 2020)
      Increased knowledge regarding the implications of gut microbiota in irritable bowel syndrome (IBS) suggests that a disturbed intestinal microenvironment (dysbiosis) might promote the development and maintenance of IBS ...

    • Gut microbiota composition during a 12-week intervention with delayed-release dimethyl fumarate in multiple sclerosis – a pilot trial 

      Storm-Larsen, Christopher; Myhr, Kjell-Morten; Farbu, Elisabeth; Midgard, Rune; Nyquist, Kaja Beate; Broch, Line; Berg-Hansen, Pål; Hov, Johannes Espolin Roksund; Holmøy, Trygve (Peer reviewed; Journal article, 2019)
      Introduction: Patients with multiple sclerosis may have a distinct gut microbiota profile. Delayed-release dimethyl fumarate is an orally administered drug for relapsing–remitting multiple sclerosis, which has been associated ...

    • Gut microbiota composition during hospitalization is associated with 60-day mortality after severe COVID-19 

      Trøseid, Marius; Holter, Jan Cato; Holm, Kristian; Vestad, Beate; Sazonova, Taisiia; Granerud, Beathe Kiland; Dyrhol-Riise, Anne Ma; Holten, Aleksander Rygh; Tonby, Kristian; Kildal, Anders Benjamin; Heggelund, Lars; Tveita, Anders Aune; Bøe, Simen; Müller, Karl Erik; Jenum, Synne; Hov, Johannes Espolin Roksund; Ueland, Thor (Journal article; Peer reviewed, 2023)
      Background Gut microbiota alterations have been reported in hospitalized COVID-19 patients, with reduced alpha diversity and altered microbiota composition related to respiratory failure. However, data regarding gut ...

    • Gut microbiota-dependent trimethylamine N-oxide associates with inflammation in common variable immunodeficiency 

      Macpherson, Magnhild Eide; Hov, Johannes Espolin Roksund; Ueland, Thor; Dahl, Tuva Børresdatter; Kummen, Martin; Otterdal, Kari; Holm, Kristian; Berge, Rolf Kristian; Mollnes, Tom Eirik; Trøseid, Marius; Halvorsen, Bente; Aukrust, Pål; Fevang, Børre; Jørgensen, Silje Fjellgård (Journal article; Peer reviewed, 2020)
      A substantial proportion of patients with common variable immunodeficiency (CVID) have inflammatory and autoimmune complications of unknown etiology. We have previously shown that systemic inflammation in CVID correlates ...

    • GWAS for autoimmune Addison's disease identifies multiple risk loci and highlights AIRE in disease susceptibility 

      Eriksson, Daniel; Røyrvik, Ellen Christine; Aranda-Guillen, Maribel; Berger, Amund Holte; Landegren, Nils; Artaza, Haydee; Hallgren, Åsa; Grytaas, Marianne; Strøm, Sara; Bratland, Eirik; Botusan, Ileana; Oftedal, Bergithe Eikeland; Breivik, Lars Ertesvåg; Vaudel, Marc; Helgeland, Øyvind; Falorni, Alberto; Jørgensen, Anders Palmstrøm; Hulting, Anna-Lena; Svartberg, Johan; Ekwall, Olov; Fougner, Kristian J; Wahlberg, Jeanette; Nedrebø, Bjørn Gunnar; Dahlqvist, Per; Study group, Norwegian Addison Registry; Study Group, Swedish Addison Registry; Knappskog, Per Morten; Wolff, Anette Susanne Bøe; Bensing, Sophie; Johansson, Stefan; Kämpe, Olof; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2021)
      Autoimmune Addison’s disease (AAD) is characterized by the autoimmune destruction of the adrenal cortex. Low prevalence and complex inheritance have long hindered successful genetic studies. We here report the first ...

    • GWAS of suicide attempt in psychiatric disorders and association with major depression polygenic risk scores 

      Mullins, Niamh; Bigdeli, Tim B.; Børglum, Anders D.; Coleman, Jonathan R.I.; Demontis, Ditte; Mehta, Divya; Power, Robert A.; Ripke, Stephan; Stahl, Eli A.; Starnawska, Anna; Anjorin, Adebayo; Corvin, Aiden; Sanders, Alan R.; Forstner, Andreas J.; Reif, Andreas; Koller, Anna C.; Świątkowska, Beata; Baune, Bernhard T.; Müller-Myhsok, Bertram; Penninx, Brenda W.J.H.; Pato, Carlos; Zai, Clement; Rujescu, Dan; Hougaard, David M.; Quested, Digby; Levinson, Douglas F.; Binder, Elisabeth B.; Byrne, Enda M.; Agerbo, Esben; Streit, Fabian; Mayoral, Fermin; Bellivier, Frank; Degenhardt, Franziska; Breen, Gerome; Morken, Gunnar; Turecki, Gustavo; Rouleau, Guy A.; Grabe, Hans J.; Völzke, Henry; Jones, Ian; Giegling, Ina; Agartz, Ingrid; Melle, Ingrid; Lawrence, Jacob; Walters, James T.R.; Strohmaier, Jana; Shi, Jianxin; Hauser, Joanna; Biernacka, Joanna M.; Vincent, John B.; Kelsoe, John; Strauss, John S.; Lissowska, Jolanta; Pimm, Jonathan; Smoller, Jordan W.; Guzman-Parra, José; Berger, Klaus; Scott, Laura J.; Jones, Lisa A.; Azevedo, M. Helena; Trzaskowski, Maciej; Kogevinas, Manolis; Rietschel, Marcella; Boks, Marco; Ising, Marcus; Grigoroiu-Serbanescu, Maria; Hamshere, Marian L.; Leboyer, Marion; Frye, Mark; Nöthen, Markus M.; Alda, Martin; Preisig, Martin; Nordentoft, Merete; Boehnke, Michael; O'Donovan, Michael C.; Owen, Michael J.; Pato, Michele T.; Renteriá, Miguel E.; Budde, Monika; Weissman, Myrna M.; Wray, Naomi R.; Bass, Nicholas; Craddock, Nicholas; Smeland, Olav Bjerkehagen; Andreassen, Ole Andreas; Mors, Ole; Gejman, Pablo V.; Sklar, Pamela; McGrath, Patrick; Hoffmann, Per; McGuffin, Peter; Lee, Phil H.; Mortensen, Preben Bo; Kahn, René S.; Ophoff, Roel A.; Adolfsson, Rolf; Van der Auwera, Sandra; Djurovic, Srdjan; Kloiber, Stefan; Heilmann-Heimbach, Stefanie; Jamain, Stéphane; Hamilton, Steven P.; McElroy, Susan L.; Lucae, Susanne; Cichon, Sven; Schulze, Thomas G.; Hansen, Thomas; Werge, Thomas; Air, Tracy M.; Nimgaonkar, Vishwajit; Appadurai, Vivek; Cahn, Wiepke; Milaneschi, Yuri; Fanous, Ayman H.; Kendler, Kenneth S.; McQuillin, Andrew; Lewis, Cathryn M. (Journal article; Peer reviewed, 2019)
      Objective: More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin and family studies suggest that the genetic etiology of suicide attempt is partially distinct from that of the psychiatric ...

    • GWAS-based pathway analysis differentiates between fluid and crystallized intelligence 

      Christoforou, Andrea; Espeseth, Thomas; Davis, G.; Fernandes, Carla P.D.; Giddaluru, Sudheer; Mattheisen, Manuel; Tenesa, A.; Harris, Sarah E.; Liewald, David C; Payton, Anthony; Ollier, W; Horan, M.; Pendleton, Neil; Haggarty, Paul; Djurovic, Srdjan; Herms, Stefan; Hoffman, P.; Cichon, Sven; Starr, John M; Lundervold, Astri; Reinvang, Ivar; Steen, Vidar Martin; Deary, Ian J; Le Hellard, Stephanie (Peer reviewed; Journal article, 2014-09)
      Cognitive abilities vary among people. About 40–50% of this variability is due to general intelligence (g), which reflects the positive correlation among individuals' scores on diverse cognitive ability tests. g is positively ...

    • Habitual Sleep Patterns and Chronic Sleep Problems in Relation to Sex, Age, and Circadian Preference in a Population-Based Sample of Norwegian Adults 

      Saxwig, Ingvild West; Bjorvatn, Bjørn; Waage, Siri (Journal article; Peer reviewed, 2023)
      Sleep patterns and problems vary in relation to internal (e.g., sex, age, circadian preference) and external (e.g., social structures) factors. The main aim of the present study was to describe habitual sleep patterns and ...

    • Habitual Sleep, Social Jetlag, and Reaction Time in Youths With Delayed Sleep–Wake Phase Disorder. A Case–Control Study 

      Saxvig, Ingvild W.; Wilhelmsen-Langeland, Ane; Pallesen, Ståle; Nordhus, Inger Hilde; Vedaa, Øystein; Bjorvatn, Bjørn (Peer reviewed; Journal article, 2019-11-12)
      The aim of this study was to explore habitual sleep, social jetlag, and day-to-day variations in sleep (measured as intra-individual standard deviation, ISD) in youths with delayed sleep–wake phase disorder (DSWPD), compared ...

    • Haemagglutination inhibition and virus microneutralisation serology assays: use of harmonised protocols and biological standards in seasonal influenza serology testing and their impact on inter-laboratory variation and assay correlation: A FLUCOP collaborative study 

      Waldock, Joanna; Remarque, Edmond J.; Zheng, Lingyi; Ho, Sammy; Hoschler, Katja; Neumann, Britta; Sediri-Schön, Hanna; Trombetta, Claudia M.; Montomoli, Emanuele; Marchi, Serena; Lapini, Giulia; Zhou, Fan; Jalloh, Sarah Larteley Lartey; Cox, Rebecca Jane; Facchini, Marzia; Castrucci, Maria Rita; Friel, Damien; Ollinger, Thierry; Caillet, Catherine; Music, Nedzad; Palladino, Giuseppe; Engelhardt, Othmar G. (Journal article; Peer reviewed, 2023)
      Introduction: The haemagglutination inhibition assay (HAI) and the virus microneutralisation assay (MN) are long-established methods for quantifying antibodies against influenza viruses. Despite their widespread use, both ...

    • Half of all hospitalised children treated with antibiotics for pneumonia did not fulfil radiological, microbiological or laboratory criteria 

      Selvåg, Maren Andrea Øvrum; Thaulow, Christian Magnus (Journal article; Peer reviewed, 2021)
      Aim Evaluating the management of paediatric pneumonia is important. We aimed to estimate the proportion of children receiving antibiotics for suspected community-acquired pneumonia (CAP) that were likely to have a bacterial ...

    • Half of children with recurrent or chronic wet cough before three years of age were symptom-free by age seven 

      Sørensen, Karen Galta; Mikalsen, Ingvild Bruun; Neven, Axel; Øymar, Knut (Journal article; Peer reviewed, 2020)
      Aim We aimed to study the natural course of recurrent episodic and chronic wet cough in preschool children, the proportion and age of resolution, and risk factors for persistent symptoms. Methods Parents of children ...

    • Hallucinating schizophrenia patients have longer left arcuate fasciculus fiber tracks: a DTI tractography study 

      Falkenberg, Liv E.; Westerhausen, René; Johnsen, Erik; Kroken, Rune Andreas; Løberg, Else-Marie; Beresniewicz, Justyna; Kazimierczak, Katarzyna Anna; Kompus, Kristiina; Ersland, Lars; Sandøy, Lydia Brunvoll; Hugdahl, Kenneth (Journal article; Peer reviewed, 2020)
      The arcuate fasciculus (AF) has been implicated in the pathology behind schizophrenia and auditory verbal hallucinations (AVHs). White matter tracts forming the arcuate fasciculus can be quantified and visualized using ...

    • Hallucinations in acutely admitted patients with psychosis, and effectiveness of risperidone, olanzapine, quetiapine, and ziprasidone: a pragmatic, randomized study 

      Johnsen, Erik; Sinkeviciute, Igne; Løberg, Else-Marie; Kroken, Rune A.; Hugdahl, Kenneth; Jørgensen, Hugo A. (Peer reviewed; Journal article, 2013-09-30)
      Background Hallucinations are prevalent in schizophrenia and related psychotic disorders and may have severe consequences for the affected patients. Antipsychotic drug trials that specifically address the anti-hallucinatory ...

    • HAMLET forms annular oligomers when deposited with phoshpolipid monolayers 

      Baumann, Anne; Gjerde, Anja Underhaug; Ying, Ming; Svanborg, Catharina; Holmsen, Holm A.; Glomm, Wilhelm; Martinez, Aurora; Halskau, Øyvind (Peer reviewed; Journal article, 2012-04)
      Recently, the anticancer activity of human α-lactalbumin made lethal to tumor cells (HAMLET) has been linked to its increased membrane affinity in vitro, at neutral pH, and ability to cause leakage relative to the inactive ...

    • HAMLET interacts with lipid membranes and perturbs their structure and integrity 

      Mossberg, Ann-Kristin; Puchades, Maja; Halskau, Øyvind; Baumann, Anne; Lanekoff, Ingela; Chao, Yinxia; Martinez, Aurora; Svanborg, Catharina; Karlsson, Roger (Peer reviewed; Journal article, 2010-01-23)
      Background Cell membrane interactions rely on lipid bilayer constituents and molecules inserted within the membrane, including specific receptors. HAMLET (human α-lactalbumin made lethal to tumor cells) is a tumoricidal ...

    • The hamster wheel: a case study on embodied narrative identity and overcoming severe obesity 

      Natvik, Eli; Råheim, Målfrid; Sviland, Randi (Journal article; Peer reviewed, 2021)
      Based in narrative phenomenology, this article describes an example of how lived time, self and bodily engagement with the social world intertwine, and how our sense of self develops. We explore this through the life story ...