Browsing Faculty of Medicine by Title
Now showing items 5059-5078 of 8833
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Longer-term quality of care, effectiveness, and cost-effectiveness of implementing a model of care for osteoarthritis: A cluster-randomized controlled trial
(Journal article; Peer reviewed, 2024)Objective: To assess the quality of care, effectiveness, and cost-effectiveness over 12 months after implementing a structured model of care for hip and knee osteoarthritis (OA) in primary healthcare as compared to usual ... -
Longevity of B-cell and T-cell responses after live attenuated influenza vaccination in children
(Peer reviewed; Journal article, 2015-05-15)Background. The live attenuated influenza vaccine (LAIV) is the preferred vaccine for children, but the mechanisms behind protective immune responses are unclear, and the duration of immunity remains to be elucidated. This ... -
The longitudinal association between the use of antihypertensive medications and 24-hour sleep in nursing homes: results from the randomized controlled COSMOS trial
(Journal article; Peer reviewed, 2021)Background Antihypertensive medication use and sleep problems are highly prevalent in nursing home patients. While it is hypothesized that blood pressure and antihypertensive medication use can affect sleep, this has not ... -
Longitudinal cerebrospinal fluid measurements show glial hypo- and hyperactivation in predementia Alzheimer’s disease
(Journal article; Peer reviewed, 2023)Background Brain innate immune activation is associated with Alzheimer’s disease (AD), but degrees of activation may vary between disease stages. Thus, brain innate immune activation must be assessed in longitudinal ... -
Longitudinal effects of adjuvant chemotherapy and lymph node staging on patient-reported outcomes in endometrial cancer survivors: a prospective cohort study
(Journal article; Peer reviewed, 2021)Background: Most patients with endometrial cancer with localized disease are effectively treated and survive for a long time. The primary treatment is hysterectomy, to which surgical staging procedures may be added to ... -
A longitudinal follow-up of autoimmune polyendocrine syndrome type 1
(Peer reviewed; Journal article, 2016-08)Context: Autoimmune polyendocrine syndrome type 1 (APS1) is a childhood-onset monogenic disease defined by the presence of two of the three major components: hypoparathyroidism, primary adrenocortical insufficiency, and ... -
Longitudinal Follow-Up of Blood Telomere Length in HIV-Exposed Uninfected Children Having Received One Year of Lopinavir/Ritonavir or Lamivudine as Prophylaxis
(Journal article; Peer reviewed, 2021)Telomere shortening can be enhanced upon human immunodeficiency virus (HIV) infection and by antiretroviral (ARV) exposures. The aim of this study was to evaluate the acute and long-term effect on telomere shortening of ... -
Longitudinal follow-up of employment status in patients with chronic fatigue syndrome after mononucleosis
(Peer reviewed; Journal article, 2015-11-26)Objective: To examine the effect of early clinical and demographic factors on occupational outcome, return to work or awarded permanent disability pension in young patients with chronic fatigue syndrome (CFS). Design: ... -
Longitudinal relationship between diabetes-specific emotional distress and follow-up HbA1c in adults with Type 1 diabetes mellitus
(Peer reviewed; Journal article, 2015-05-18)Aim To examine whether diabetes-specific emotional distress was related to follow-up glycaemic control in adults with Type 1 diabetes mellitus. Methods Adults with Type 1 diabetes mellitus completed the Diabetes Distress ... -
A longitudinal study of dental erosion and associated lifestyle factors in a group of Swedish children and adolescents
(Doctoral thesis, 2017-12-15)Background: Erosive wear has been observed among Swedish adolescents, but with unknown prevalence. High prevalence of dental erosion is reported from different parts of the world, and often linked to an increasing consumption ... -
A Longitudinal Study of the Association between Mammographic Density and Gene Expression in Normal Breast Tissue
(Peer reviewed; Journal article, 2019-01-06)High mammographic density (MD) is associated with a 4–6 times increase in breast cancer risk. For post-menopausal women,MD often decreases over time, but little is known about the underlying biological mechanisms. MD ... -
A longitudinal study of the pulmonary mycobiome in subjects with and without chronic obstructive pulmonary disease
(Journal article; Peer reviewed, 2022-05-12)Background: Few studies have examined the stability of the pulmonary mycobiome. We report longitudinal changes in the oral and pulmonary mycobiome of participants with and without COPD in a large-scale bronchoscopy study ... -
Longitudinal Transcriptomic Analysis of Human Cortical Spheroids Identifies Axonal Dysregulation in the Prenatal Brain as a Mediator of Genetic Risk for Schizophrenia
(Journal article; Peer reviewed, 2024)Background Schizophrenia (SCZ) has a known neurodevelopmental etiology, but limited access to human prenatal brain tissue hampers the investigation of basic disease mechanisms in early brain development. Here, we elucidate ... -
Longterm follow-up in European respiratory health studies - patterns and implications
(Peer reviewed; Journal article, 2014-04-16)Background: Selection bias is a systematic error in epidemiologic studies that may seriously distort true measures of associations between exposure and disease. Observational studies are highly susceptible to selection ... -
Looking forward to the next 15 years: innovation and new pathways for research in health equity
(Peer reviewed; Journal article, 2017)Since our launch in 2002, the International Journal for Equity in Health (IJEqH) has furthered our collective understanding of equity in health and health services by providing a platform on which academics and practitioners ... -
Lopinavir/Ritonavir versus Lamivudine peri-exposure prophylaxis to prevent HIV-1 transmission by breastfeeding: the PROMISE-PEP trial Protocol ANRS 12174
(Peer reviewed; Journal article, 2012-10-06)Background: Postnatal transmission of HIV-1 through breast milk remains an unsolved challenge in many resource-poor settings where replacement feeding is not a safe alternative. WHO now recommends breastfeeding of infants ... -
Loss of COPZ1 induces NCOA4 mediated autophagy and ferroptosis in glioblastoma cell lines
(Journal article; Peer reviewed, 2021)Dysregulated iron metabolism is a hallmark of many cancers, including glioblastoma (GBM). However, its role in tumor progression remains unclear. Herein, we identified coatomer protein complex subunit zeta 1 (COPZ1) as a ... -
Loss of epigenetic suppression of retrotransposons with oncogenic potential in aging mammary luminal epithelial cells
(Journal article; Peer reviewed, 2023)A primary function of DNA methylation in mammalian genomes is to repress transposable elements (TEs). The widespread methylation loss that is commonly observed in cancer cells results in the loss of epigenetic repression ... -
Loss of health certificates among offshore petroleum workers on the Norwegian Continental Shelf 2002-2010
(Peer reviewed; Journal article, 2011)Background: A health certificate is required to work on the offshore petroleum installations of the Norwegian Shelf. Loss of health certificate (“loss of licence”, LOL) may cause economic problems for the individual worker. ... -
Loss of life years due to unavailable helicopter emergency medical service: a single base study from a rural area of Norway
(Peer reviewed; Journal article, 2019)Background: Despite the potential benefits of physician-staffed Helicopter Emergency Medical Service (HEMS), many dispatches to primary HEMS missions in Norway are cancelled before patient encounter. Information is sparse ...