Blar i Faculty of Medicine på tittel
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Role of a Digital Clinical Decision–Support System in General Practitioners’ Management of COPD in Norway
(Journal article; Peer reviewed, 2021)Background: The study investigated if a web-based clinical decision–support system (CDSS) tool would improve general practitioners’ (GPs) accuracy of diagnosis and classification of patients with chronic obstructive pulmonary ... -
The Role of a Mission Organization in Building a Sustainable Government Hospital in Southern Ethiopia
(Journal article, 2020)In 1950, the Norwegian Lutheran Mission (NLM) began holistic mission work, including health work in Yirga Alem in Sidama in Southern Ethiopia. The hospital, which had served as a military hospital during the Italian war ... -
Role of Adipocyte SLC7A10 and Amino Acid Metabolism in Obesity and Insulin Resistance
(Doctoral thesis, 2020-12-18)Obesity is a rising global concern, associated with increased risk of developing metabolic syndrome, insulin resistance and type 2 diabetes. Chronic availability of excess nutrients may promote adipocyte dysfunction, ... -
The Role of Age in Cellular Responses to Microenvironmental Cues as a Breast Cancer Susceptibility Factor
(Doctoral thesis, 2016-05-09)Aging is the critical risk factor for many forms of cancer. We used the mammary gland as a model system to study the impact of age on human epithelia in which age is the greatest risk factor for cancer. Dysfunctional ... -
The role of anti-citrullinated protein antibody reactivities in an inception cohort of patients with rheumatoid arthritis receiving treat-to-target therapy
(Peer reviewed; Journal article, 2018-07-13)Background: Anti-citrullinated protein antibody (ACPA) reactivities precede clinical onset of rheumatoid arthritis (RA), and it has been suggested that ACPA reactivities towards distinct target proteins may be associated ... -
The role of arginine and arginine-metabolizing enzymes during Giardia - host cell interactions in vitro
(Peer reviewed; Journal article, 2013-11-14)Background: Arginine is a conditionally essential amino acid important in growing individuals and under nonhomeostatic conditions/disease. Many pathogens interfere with arginine-utilization in host cells, especially nitric ... -
The role of autoantibodies in cell mediated autoimmune Addison`s disease
(Master thesis, 2012-05-31)Background: Addison`s disease (primary adrenal insufficiency) is a prototypic organ-specific autoimmune disease affecting the adrenal cortex. Autoimmune Addison`s disease (AAD) is often characterized by autoantibodies ... -
The Role of Axl in Cancer and Stem Cell Plasticity: in vivo Lineage Tracing and Imaging Mass Cytometry Analysis
(Master thesis, 2019-11-14) -
The role of Axl in melanoma metastasis
(Master thesis, 2015-05-31)Melanoma is a highly invasive and metastatic cancer, thus understanding the mechanism of melanoma metastasis is a major issue. In our study, the objective is to elucidate the role of the receptor tyrosine kinase Axl in ... -
Role of Caveolin-1 in Hypoxia and Proneural to Mesenchymal Transition of Glioblastoma
(Master thesis, 2018-06-29)Glioblastomas (GBM), a grade IV astrocytoma, is the most common and aggressive primary brain tumors in adults, associated with short survival and uniformly fatal outcome irrespective of treatment. GBM is highly heterogeneous ... -
The Role of Diet in Irritable Bowel Syndrome with special reference to Gut Neuroendocrine System
(Doctoral thesis, 2015-08-28)Background: The majority of the patients with irritable bowel syndrome (IBS) believe that diet triggers their symptoms, which affect the quality of their lives. The pathophysiology of IBS is not exactly known, however, the ... -
The role of diet in the pathophysiology and management of irritable bowel syndrome
(Journal article; Peer reviewed, 2021)Irritable bowel syndrome (IBS) is a chronic gastrointestinal (GI) disorder that reportedly affects 5% to 20% of the world population. The etiology of IBS is not completely understood, but diet appears to play an important ... -
Role of dietary carbohydrate quality and quantity in visceral obesity reduction : Results from a randomized controlled trial (CARBFUNC)
(Doctoral thesis, 2022-03-25)Background: Increased visceral adipose tissue (VAT) volume is associated with common lifestyle diseases and poses an increasing health challenge worldwide. There is a great need for effective approaches that result in ... -
The role of dietary fat and carbohydrates in development of adipose tissue inflammation
(Master thesis, 2009-06-02)Obesity is considered as a chronic low-grade inflammatory condition, which can be characterized by increased levels of the proinflammatory cytokines such as TNF-α and IL-6, and macrophage infiltration in adipose tissue. ... -
Role of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development
(Peer reviewed; Journal article, 2013-11-12)Background: Endometrial cancer incidence is continuing to rise in the wake of the current ageing and obesity epidemics. Much of the risk for endometrial cancer development is influenced by the environment and lifestyle. ... -
The role of epigenetics in multi-generational transmission of asthma: An NIAID workshop report-based narrative review
(Journal article; Peer reviewed, 2022)There is mounting evidence that environmental exposures can result in effects on health that can be transmitted across generations, without the need for a direct exposure to the original factor, for example, the effect of ... -
The role of evidence in the decision-making process of selecting essential medicines in developing countries: the case of Tanzania
(Peer reviewed; Journal article, 2014-01-08)Background: Insufficient access to essential medicines is a major health challenge in developing countries. Despite the importance of Standard Treatment Guidelines and National Essential Medicine Lists in facilitating ... -
Role of evolutionary conserved residues in integrin α11 cytoplasmic tail
(Master thesis, 2021-05-31)Integrins are cell surface receptors, present in the plasma membrane of cells. The integrin family is composed of 18 α subunits and 8 β subunits, which can combine non-covalently to form 24 different integrin heterodimers. ... -
The role of fat distribution and inflammation in the origin of endometrial cancer, study protocol of the ENDOCRINE study
(Journal article; Peer reviewed, 2022)Background Obesity is a growing problem worldwide, especially in countries with improved socioeconomic circumstances. Also, in the Netherlands the incidence of overweight and obesity is rising. There is increasing evidence ... -
Role of fungal burden in risk stratification of HIV-negative patients with Pneumocystis pneumonia: A 12-year, retrospective, observational, multicenter cohort
(Journal article; Peer reviewed, 2023)Objectives This study aimed to explore the role of fungal burden in risk stratification of patients without HIV-negative patients with Pneumocystis pneumonia (PCP). Methods This was a retrospective analysis of the ...