Blar i Faculty of Medicine på tittel
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Biological responses of dental pulp stem cells to surfaces modified by collagen 1 and fibronectin
(Master thesis, 2014-01-18)Collagen 1 and fibronectin are extracellular matrix proteins that contribute in cell activity and involve in regulating dental pulp stem cells. The purpose of this in vitro study was to investigate the effect of collagen ... -
Biological Responses to Aliphatic Polyester Scaffolds for Bone Tissue Engineering Applications
(Doctoral thesis, 2010-12-03)Currently, various strategies are used to stimulate healing of bone defects and restore lost alveolar bone and periodontal support. The concept of tissue engineering has emerged as a valid approach to the current therapies ... -
Biological variation of cardiac myosin-binding protein C in healthy individuals
(Journal article; Peer reviewed, 2021)Objectives Cardiac myosin-binding protein C (cMyC) is a novel biomarker of myocardial injury, with a promising role in the triage and risk stratification of patients presenting with acute cardiac disease. In this study, ... -
Biological variation of secretoneurin; a novel cardiovascular biomarker implicated in arrhythmogenesis
(Journal article, 2021)Background Secretoneurin is a novel prognostic biomarker that may predict mortality in heart failure and the occurrence of ventricular arrhythmias. This study reports the within subject variation (CVI), between subject ... -
The biology of aging and cancer: A brief overview of shared and divergent molecular hallmarks
(Peer reviewed; Journal article, 2017-10)Aging is the inevitable time-dependent decline in physiological organ function and is a major risk factor for cancer development. Due to advances in health care, hygiene control and food availability, life expectancy is ... -
Biomarker and pathology studies in neurodegenerative cognitive impairment
(Doctoral thesis, 2019-10-16)Background: Dementia is a major cause of functional impairment and early death in older age groups. Neurodegenerative disorders are the most common cause of dementia. The most frequent neuropathological lesions include ... -
Biomarker changes as surrogate endpoints in early-phase trials in heart failure with reduced ejection fraction
(Journal article; Peer reviewed, 2022)Aims No biomarker has achieved widespread acceptance as a surrogate endpoint for early-phase heart failure (HF) trials. We assessed whether changes over time in a panel of plasma biomarkers were associated with subsequent ... -
Biomarker profiles in serum and saliva of experimental Sjögren's syndrome: associations with specific autoimmune manifestations
(Peer reviewed; Journal article, 2008-02-20)Introduction Sjögren's syndrome (SS) is a systemic autoimmune disease that mainly targets the exocrine glands. The aim of this study was to investigate the involvement of 87 proteins measured in serum and 75 proteins ... -
Biomarker prognostication of cognitive impairment may be feasible even in out-of hospital cardical arrest survivors with good neurological outcome
(Journal article; Peer reviewed, 2021)Background Patients surviving out-of hospital cardicac arrest, with good neurological outcome according to Cerebral Performance Category, frequently have neuropsychological impairment. We studied whether biomarker data ... -
Biomarker signature and pathophysiological pathways in patients with chronic heart failure and metabolic syndrome
(Journal article; Peer reviewed, 2023)Aim The comorbidities that collectively define metabolic syndrome are common in patients with heart failure. However, the role of metabolic syndrome in the pathophysiology of heart failure is not well understood. We ... -
Biomarkers and Algorithms for the Diagnosis of Vitamin B12 Deficiency
(Peer reviewed; Journal article, 2016-06-27)Vitamin B12 (cobalamin, Cbl, B12) is an indispensable water-soluble micronutrient that serves as a coenzyme for cytosolic methionine synthase (MS) and mitochondrial methylmalonyl-CoA mutase (MCM). Deficiency of Cbl, whether ... -
Biomarkers and echocardiographic predictors of myocardial dysfunction in patients with hypertension
(Peer reviewed; Journal article, 2015-03-09)The study aimed to identify early echocardiographic and circulating biomarkers of heart failure (HF) in hypertensive patients with normal resting echocardiography. Echocardiography at rest and during exercise, and selected ... -
Biomarkers and Fatty Fish Intake: A Randomized Controlled Trial in Norwegian Preschool Children
(Journal article; Peer reviewed, 2021)Background Biomarkers such as omega-3 (n–3) PUFAs, urinary iodine concentration (UIC), 1-methylhistidine (1-MH), and trimethylamine N-oxide (TMAO) have been associated with fish intake in observational studies, but data ... -
Biomarkers and risk factors of neurodegeneration in multiple sclerosis
(Doctoral thesis, 2023-02-10)Bakgrunn og mål: Markører på nevrodegenerasjon er tett knyttet til klinisk funksjonsnedsettelse og sykdomsprogresjon hos pasienter med multippel sklerose (MS). Slike biomarkører kan derfor bidra til å identifisere potensielle ... -
Biomarkers for Diabetes Mellitus in advanced Peripheral Arterial Disease. Diagnostic performance and outcome prediction of HbA1c, fasting plasma glucose and the oral glucose tolerance test
(Doctoral thesis, 2019-05-14)Background: At present, the diagnosis of diabetes mellitus (DM) is based on the result from either of three tests; HbA1c, fasting plasma glucose (FPG) or 2-hour post glucose-load value following an oral glucose tolerance ... -
Biomarkers in breast cancer, with special focus on tumor cell proliferation
(Doctoral thesis, 2016-10-31)Background: Breast cancer is a heterogeneous disease encompassing distinct subtypes that differ in incidence and prognosis. Better characterization of established biomarkers and exploration of novel biomarkers and possible ... -
Biomarkers of inflammation and left ventricular remodelling in psoriasis patients treated with infliximab
(Journal article; Peer reviewed, 2022)Objective: Psoriasis is an immune mediated disorder associated with T cell activation and cardiovascular disease (CVD). We explored the association of inflammation with left ventricular (LV) remodelling in psoriasis patients ... -
Biomarkers of one-carbon metabolism and B-vitamin status : Targeted metabolomics in rats and humans exploring the effects of PPARα-activation and dietary composition
(Doctoral thesis, 2019-10-04)BACKGROUND: One-carbon metabolism is an overarching term describing central metabolic pathways involved in the transfer of one-carbon units. These include the methionine-homocysteine and folate cycles, as well as the choline ... -
Biomarkers related to carotid intima-media thickness and plaques in long-term survivors of ischemic stroke
(Peer reviewed; Journal article, 2015-05-08)Lifestyle risk factors, inflammation and genetics play a role in the development of atherosclerosis. We therefore studied Fc gamma receptor (FcγR) polymorphisms, interleukin (IL)-10 polymorphisms and other biomarkers related ... -
Biomass fuel use for cooking in Nepalese families and child cognitive abilities, results from a community-based study
(Journal article; Peer reviewed, 2022)Background Biomass fuel use for cooking is widespread in low to middle income countries. Studies on the association between biomass fuel use and cognitive abilities in children are limited. Objective To examine the association ...