Blar i Faculty of Medicine på forfatter "Berven, Frode S."
-
Arachnoid cysts do not contain cerebrospinal fluid: A comparative chemical analysis of arachnoid cyst fluid and cerebrospinal fluid in adults
Berle, Magnus; Wester, Knut; Ulvik, Rune Johan; Kroksveen, Ann Cathrine; Haaland, Øystein; Amiry-Moghaddam, Mahmood; Berven, Frode S. (Peer reviewed; Journal article, 2010-06-10)Background Arachnoid cyst (AC) fluid has not previously been compared with cerebrospinal fluid (CSF) from the same patient. ACs are commonly referred to as containing "CSF-like fluid". The objective of this study was to ... -
Compomics-utilities: an open-source Java library for computational proteomics
Barsnes, Harald; Vaudel, Marc; Colaert, Niklaas; Helsens, Kenny; Sickmann, Albert; Berven, Frode S.; Martens, Lennart (Peer reviewed; Journal article, 2011-03-08)Background The growing interest in the field of proteomics has increased the demand for software tools and applications that process and analyze the resulting data. And even though the purpose of these tools can vary ... -
Comprehensive Analysis of Exported Proteins from Mycobacterium tuberculosis H37Rv
Målen, Hiwa; Berven, Frode S.; Fladmark, Kari Espolin; Wiker, Harald G. (Proteomics, Peer reviewed; Journal article, 2007-04-21)Proteins secreted by Mycobacterium tuberculosis play an essential role in the pathogenesis of tuberculosis. The culture filtrates of M. tuberculosis H37Rv made by Sadamu Nagai (Japan), are considerably enriched for secreted ... -
Effects of blood contamination and the rostro-caudal gradient on the human cerebrospinal fluid proteome
Aasebø, Elise; Opsahl, Jill Anette; Bjørlykke, Yngvild; Myhr, Kjell-Morten; Kroksveen, Ann Cathrine; Berven, Frode S. (Peer reviewed; Journal article, 2014-03-05)Over the last years there has been an increased focus on the importance of knowing the effect of pre-analytical influence on the proteomes under study, particularly in the field of biomarker discovery. We present three ... -
Exploring the human plasma proteome for humoral mediators of remote ischemic preconditioning - A word of caution
Helgeland, Erik; Breivik, Lars Ertesvåg; Vaudel, Marc; Svendsen, Øyvind Sverre; Garberg, Hilde Kristin; Nordrehaug, Jan Erik; Berven, Frode S.; Jonassen, Anne Kristin (Peer reviewed; Journal article, 2014-10-15)Despite major advances in early revascularization techniques, cardiovascular diseases are still the leading cause of death worldwide, and myocardial infarctions contribute heavily to this. Over the past decades, it has ... -
Molecular mechanisms of nutlin-3 involve acetylation of p53, histones and heat shock proteins in acute myeloid leukemia
Haaland, Ingvild; Opsahl, Jill Anette; Berven, Frode S.; Reikvam, Håkon; Fredly, Hanne Kristin; Haugse, Ragnhild; Thiede, Bernd; McCormack, Emmet; Lain, Sonia; Bruserud, Øystein; Gjertsen, Bjørn Tore (Peer reviewed; Journal article, 2014-05-21)Background: The small-molecule MDM2 antagonist nutlin-3 has proved to be an effective p53 activating therapeutic compound in several preclinical cancer models, including acute myeloid leukemia (AML). We and others have ... -
Protein profiling reveals inter-individual protein homogeneity of arachnoid cyst fluid and high qualitative similarity to cerebrospinal fluid
Berle, Magnus; Kroksveen, Ann Cathrine; Haaland, Øystein; Aye, Thin T.; Opsahl, Jill Anette; Oveland, Eystein; Wester, Knut; Ulvik, Rune Johan; Helland, Christian Andre; Berven, Frode S. (Peer reviewed; Journal article, 2011-05-20)Background: The mechanisms behind formation and filling of intracranial arachnoid cysts (AC) are poorly understood. The aim of this study was to evaluate AC fluid by proteomics to gain further knowledge about ACs. Two goals ... -
Proteomic analysis of formalin-fixed paraffin-embedded glomeruli suggests depletion of glomerular filtration barrier proteins in two-kidney one-clip hypertensive rats
Finne, Kenneth; Vethe, Heidrun; Skogstrand, Trude; Leh, Sabine Maria; Dahl, Tone Dolva; Tenstad, Olav; Berven, Frode S.; Reed, Rolf K.; Vikse, Bjørn Egil (Peer reviewed; Journal article, 2014-08-16)Background It is well known that hypertension may cause glomerular damage, but the molecular mechanisms involved are still incompletely understood. Methods In the present study, we used formalin-fixed paraffin-embedded ... -
Quantitative proteomics comparison of arachnoid cyst fluid and cerebrospinal fluid collected perioperatively from arachnoid cyst patients
Berle, Magnus; Kroksveen, Ann Cathrine; Garberg, Hilde Kristin; Aarhus, Mads; Haaland, Øystein; Wester, Knut; Ulvik, Rune Johan; Helland, Christian Andre; Berven, Frode S. (Peer reviewed; Journal article, 2013-04-29)Background: There is little knowledge concerning the content and the mechanisms of filling of arachnoid cysts. The aim of this study was to compare the protein content of arachnoid cysts and cerebrospinal fluid by quantitative ...