Blar i Faculty of Medicine på forfatter "Browning, Jeffrey L."
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Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjogren's syndrome in salivary glands of non-obese diabetic mice
Gatumu, Margaret Karimi; Skarstein, Kathrine; Papandile, Adrian; Browning, Jeffrey L.; Fava, Roy A.; Bolstad, Anne Isine (Peer reviewed; Journal article, 2009-02-18)Introduction The lymphotoxin-beta receptor (LTβR) pathway is important in the development and maintenance of lymphoid structures. Blocking this pathway has proven beneficial in murine models of autoimmune diseases such as ... -
Lymphotoxin-beta Receptor blockade reduces CXCL13 in Lacrimal Glands and improves Corneal integrity in the NOD Model of Sjögren's Syndrome
Fava, Roy A.; Kennedy, Susan M.; Wood, Sheryl G.; Bolstad, Anne Isine; Bienkowska, Jadwiga; Papandile, Adrian; Kelly, John A.; Mavragani, Clio P.; Gatumu, Margaret Karimi; Skarstein, Kathrine; Browning, Jeffrey L. (Peer reviewed; Journal article, 2011-11-01)Introduction: In Sjögren’s syndrome, keratoconjunctivitis sicca (dry eye) is associated with infiltration of lacrimal glands by leukocytes and consequent losses of tear-fluid production and the integrity of the ocular ...