Blar i Faculty of Medicine på emneord "Chemoresistance"
Viser treff 1-2 av 2
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Alterations of the retinoblastoma gene in metastatic breast cancer
(Peer reviewed; Journal article, 2011-01-21)Germline mutations affecting the retinoblastoma gene (RB1) predispose to inherited retinoblastomas but also other malignancies, including breast cancer. While somatic RB1 mutations have been detected in different malignancies, ... -
Cancer stem cells as mediators of treatment resistance in brain tumors: Status and controversies
(Peer reviewed; Journal article, 2007-11)Malignant primary brain tumors are characterized by a short median survival and an almost 100% tumorrelated mortality. Despite the addition of new chemotherapy regimes, the overall survival has improved marginally, and ...