Blar i Faculty of Medicine på forfatter "Harthug, Stig"
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Adverse events and in-hospital mortality: An analysis of all deaths in a Norwegian health trust during 2011
Flaatten, Hans; Brattebø, Guttorm; Alme, Bjørn Arild; Berge, Kjersti; Rosland, Jan Henrik; Viste, Asgaut; Bertelsen, Bjørn; Harthug, Stig; Aardal, Sidsel (Peer reviewed; Journal article, 2017-07-06)Background: The estimated number of in-hospitals deaths due to adverse events is often different when using data from deceased patients compared with that of a population experiencing adverse events. Methods: The study was ... -
Antibiotic use in children before, during and after hospitalisation
Thaulow, Christian Magnus; Blix, Hege Salvesen; Nilsen, Roy Miodini; Eriksen, Beate Horsberg; Wathne, Jannicke Slettli; Berild, Dag; Harthug, Stig (Journal article; Peer reviewed, 2022)Purpose: To investigate ambulatory antibiotic use in children during 1 year before and 1 year after in-hospital antibiotic exposure compared to children from the general population that had not received antibiotics ... -
Antimicrobial resistance predicts death in Tanzanian children with bloodstream infections: a prospective cohort study
Blomberg, Bjørn; Manji, Karim P.; Urassa, Willy K.; Tamim, Bushir S.; Mwakagile, Davis S. M.; Jureen, Roland; Msangi, Viola; Tellevik, Marit Gjerde; Holberg-Petersen, Mona; Harthug, Stig; Maselle, Samwel Y.; Langeland, Nina (Peer reviewed; Journal article, 2007-05-22)Background: Bloodstream infection is a common cause of hospitalization, morbidity and death in children. The impact of antimicrobial resistance and HIV infection on outcome is not firmly established. Methods: We assessed ... -
Are infants exposed to antimicrobials during the first 3 months of life at increased risk of recurrent use? An explorative data-linkage study
Thaulow, Christian Magnus; Harthug, Stig; Nilsen, Roy Miodini; Eriksen, Beate Horsberg; Wathne, Jannicke Slettli; Berild, Dag; Blix, Hege Salvesen (Journal article; Peer reviewed, 2022)Objectives: To investigate whether infants exposed to antimicrobials in hospital during the first 3 months of life had an increased risk of ambulatory antimicrobial use during the following year compared with infants not ... -
The association between adherence to national antibiotic guidelines and mortality, readmission and length of stay in hospital inpatients: results from a Norwegian multicentre, observational cohort study
Wathne, Jannicke Slettli; Harthug, Stig; Kleppe, Lars Kåre Selland; Blix, Hege Salvesen; Nilsen, Roy Miodini; Charani, Esmita; Smith, Ingrid (Peer reviewed; Journal article, 2019-04-15)Background: Clinical antibiotic prescribing guidelines are essential in defining responsible use in the local context. Our objective was to investigate the association between adherence to national antibiotic prescribing ... -
Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study
Mehl, Arne; Åsvold, Bjørn Olav; Lydersen, Stian; Paulsen, Julie; Solligård, Erik; Damås, Jan Kristian; Harthug, Stig; Edna, Tom-Harald (Peer reviewed; Journal article, 2017-03-11)Background: Studies from several countries indicate that the incidence and mortality of bloodstream infection (BSI) have been increasing over time. Methods: We studied the burden of disease and death related to BSI in a ... -
Causal Analysis of World Health Organization's Surgical Safety Checklist Implementation Quality and Impact on Care Processes and Patient Outcomes: Secondary Analysis From a Large Stepped Wedge Cluster Randomized Controlled Trial in Norway
Haugen, Arvid Steinar; Wæhle, Hilde Valen; Almeland, Stian Kreken; Harthug, Stig; Sevdalis, Nick; Eide, Geir Egil; Nortvedt, Monica Wammen; Smith, Ingrid; Softeland, Eirik (Peer reviewed; Journal article, 2019)Objective: We hypothesize that high-quality implementation of the World Health Organization's Surgical Safety Checklist (SSC) will lead to improved care processes and subsequently reduction of peri- and postoperative ... -
Development and validation of patients' surgical safety checklist
Harris, Kristin; Søfteland, Eirik; Moi, Asgjerd Litleré; Harthug, Stig; Ravnøy, Mette; Storesund, Anette; Jurmy, Elaheh; Thakkar, Bhaumik; Haaverstad, Rune; Skeie, Eli; Valen, Hilde Wæhle; Sevdalis, Nick; Haugen, Arvid Steinar (Journal article; Peer reviewed, 2022)Background: Poor uptake and understanding of critical perioperative information represent a major safety risk for surgical patients. Implementing a patient-driven surgical safety checklist might enhance the way critical ... -
Discharge care quality in hospitalised elderly patients: Extended validation of the Discharge Care Experiences Survey
Boge, Ranveig Marie; Haugen, Arvid Steinar; Nilsen, Roy Miodini; Bruvik, Frøydis Kristine; Harthug, Stig (Peer reviewed; Journal article, 2019)Background: The Discharge Care Experiences Survey (DICARES) was previously developed to measure quality of discharge care in elderly patients (≥ 65 years). The objective of this study was to test the factorial validity of ... -
Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study
Husabø, Gunnar; Nilsen, Roy Miodini; Flaatten, Hans; Solligård, Erik; Frich, Jan C; Bondevik, Gunnar Tschudi; Braut, Geir Sverre; Walshe, Kieran; Harthug, Stig; Hovlid, Einar (Peer reviewed; Journal article, 2020-01-22)Background: Early recognition of sepsis is critical for timely initiation of treatment. The first objective of this study was to assess the timeliness of diagnostic procedures for recognizing sepsis in emergency departments. ... -
The effect of antibiotic stewardship interventions with stakeholder involvement in hospital settings: A multicentre, cluster randomized controlled intervention study
Wathne, Jannicke Slettli; Kleppe, Lars Kåre Selland; Harthug, Stig; Blix, Hege Salvesen; Nilsen, Roy Miodini; Charani, Esmita; Smith, Ingrid (Peer reviewed; Journal article, 2018-09-10)Background: There is limited evidence from multicenter, randomized controlled studies to inform planning and implementation of antibiotic stewardship interventions in hospitals. Methods: A cluster randomized, controlled, ... -
Effect of the World Health Organization Checklist on Patient Outcomes: A Stepped Wedge Cluster Randomized Controlled Trial
Haugen, Arvid Steinar; Søfteland, Eirik; Almeland, Stian Kreken; Sevdalis, Nick; Vonen, Barthold; Eide, Geir Egil; Nortvedt, Monica Wammen; Harthug, Stig (Peer reviewed; Journal article, 2015-05)Objectives: We hypothesized reduction of 30 days’ in-hospital morbidity, mortality, and length of stay postimplementation of the World Health Organization’s Surgical Safety Checklist (SSC). Background: Reductions of morbidity ... -
Effects of external inspection on sepsis detection and treatment: a study protocol for a quasiexperimental study with a stepped-wedge design
Hovlid, Einar; Frich, Jan C; Walshe, Kieran; Nilsen, Roy Miodini; Flaatten, Hans; Braut, Geir Sverre; Helgeland, Jon; Teig, Inger Lise; Harthug, Stig (Peer reviewed; Journal article, 2017)Introduction: Inspections are widely used in health care as a means to improve the health services delivered to patients. Despite their widespread use, there is little evidence of their effect. The mechanisms for how ... -
Effects of external inspections on sepsis detection and treatment: a stepped-wedge study With cluster-level randomisation
Husabø, Gunnar; Nilsen, Roy Miodini; Solligård, Erik; Flaatten, Hans; Walshe, Kieran; Frich, Jan C; Bondevik, Gunnar Tschudi; Braut, Geir Sverre; Helgeland, Jon; Harthug, Stig; Hovlid, Einar (Journal article; Peer reviewed, 2020)Objective To evaluate the effects of external inspections on (1) hospital emergency departments’ clinical processes for detecting and treating sepsis and (2) length of hospital stay and 30-day mortality. Design Incomplete ... -
Elderly patients’ (≥65 years) experiences associated with discharge; Development, validity and reliability of the Discharge Care Experiences Survey
Boge, Ranveig Marie; Haugen, Arvid Steinar; Nilsen, Roy Miodini; Harthug, Stig (Peer reviewed; Journal article, 2018-11-07)Background: A review of the literature reveals a lack of validated instruments that particularly measure quality in the hospital discharge process. This study aims to develop and validate a survey instrument feasible for ... -
Factors influencing the development of evidence-based practice among nurses: a self-report survey
Dalheim, Anne; Harthug, Stig; Nilsen, Roy Miodini; Nortvedt, Monica Wammen (Peer reviewed; Journal article, 2012-10-24)Background: Health authorities in several countries have decided that the health care services should be evidence-based. Recent research indicates that evidence-based practice may be more successfully implemented if the ... -
Feasibility of implementing a surgical patient safety checklist: prospective cross-sectional evaluation
Harris, Kristin; Søfteland, Eirik; Moi, Asgjerd Litleré; Harthug, Stig; Ravnøy, Mette; Storesund, Anette; Jurmy, Elaheh; Skeie, Eli; Wæhle, Hilde Valen; Sevdalis, Nick; Haugen, Arvid Steinar (Journal article; Peer reviewed, 2023)Background The World Health Organization’s Global Patient Safety Action Plan 2021–2030 call for attention to patient and family involvement to reduce preventable patient harm. Existing evidence indicates that patients’ ... -
How does the WHO Surgical Safety Checklist fit with existing perioperative risk management strategies? An ethnographic study across surgical specialties
Wæhle, Hilde Valen; Haugen, Arvid Steinar; Wiig, Siri; Softeland, Eirik; Sevdalis, Nick; Harthug, Stig (Journal article; Peer reviewed, 2020)Background The World Health Organization (WHO) Surgical Safety Checklist (SSC) has demonstrated beneficial impacts on a range of patient- and team outcomes, though variation in SSC implementation and staffʼs perception ... -
Identifying targets for antibiotic stewardship interventions through analysis of the antibiotic prescribing process in hospitals - a multicentre observational cohort study
Wathne, Jannicke Slettli; Skodvin, Brita; Charani, Esmita; Harthug, Stig; Blix, Hege Salvesen; Nilsen, Roy Miodini; Kleppe, Lars Kåre Selland; Vukovic, Marta; Smith, Ingrid (Journal article; Peer reviewed, 2020)Background: In order to change antibiotic prescribing behaviour, we need to understand the prescribing process. The aim of this study was to identify targets for antibiotic stewardship interventions in hospitals through ... -
Impact of the Norwegian National Patient Safety Program on implementation of the WHO Surgical Safety Checklist and on perioperative safety culture
Haugen, Arvid Steinar; Søfteland, Eirik; Sevdalis, Nick; Eide, Geir Egil; Nortvedt, Monica Wammen; Vincent, Charles; Harthug, Stig (Journal article; Peer reviewed, 2020)Objectives Our primary objective was to study the impact of the Norwegian National Patient Safety Campaign and Program on Surgical Safety Checklist (SSC) implementation and on safety culture. Secondary objective was ...