Blar i Faculty of Medicine på emneord "Neopterin"
Viser treff 1-5 av 5
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Cellular immune activity biomarker neopterin is associated hyperlipidemia: results from a large population-based study
(Peer reviewed; Journal article, 2016-02-25)Background: Increased serum neopterin had been described in older age two decades ago. Neopterin is a biomarker of systemic adaptive immune activation that could be potentially implicated in metabolic syndrome (MetS). ... -
High neopterin and IP-10 levels in cerebrospinal fluid are associated with neurotoxic tryptophan metabolites in acute central nervous system infections
(Peer reviewed; Journal article, 2018-11-23)Background The host response to intruders in the central nervous system (CNS) may be beneficial but could also be harmful and responsible for neurologic symptoms and sequelae in CNS infections. This immune response induces ... -
Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study
(Peer reviewed; Journal article, 2014-04-24)The risk of osteoporosis increases in inflammatory disorders. In cell-mediated immune activation, interferon (IFN)-γ stimulates macrophage release of neopterin and increases the activity of indoleamine 2,3-dioxygenase ... -
Interferon gamma (IFN-γ)-mediated inflammation and the kynurenine pathway in relation to risk of hip fractures: The Hordaland Health Study
(Peer reviewed; Journal article, 2014-05-10)Summary The cytokine interferon gamma (IFN-γ) stimulates neopterin release and tryptophan degradation into kynurenines through the kynurenine pathway. High levels of neopterin were associated with increased hip fracture ... -
Interferon-γ–induced inflammatory markers and the risk of cancer: The Hordaland Health Study
(Peer reviewed; Journal article, 2014-06-19)Background It has been reported that interferon-γ (IFN-γ)–induced inflammatory markers, such as circulating neopterin and kynurenine-to-tryptophan ratio (KTR), are increased in patients with cancer and are also a predictor ...