Browsing Bergen Open Research Archive by Title
Now showing items 22019-22038 of 34347
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Novel STAT3 Inhibitors Targeting STAT3 Dimerization by Binding to the STAT3 SH2 Domain
(Journal article; Peer reviewed, 2022)Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In silico computational modeling, drug affinity responsive target ... -
A novel synthesis of tin oxide thin films by the sol-gel process for optoelectronic applications
(Peer reviewed; Journal article, 2015)A novel and simple chemical method based on sol-gel processing was proposed to deposit metastable orthorhombic tin oxide (SnOx) thin films on glass substrates at room temperature. The resultant samples are labeled according ... -
A novel synthesis of tin oxide thin films by the sol-gel process for optoelectronic applications
(Peer reviewed; Journal article, 2015-02-13)A novel and simple chemical method based on sol-gel processing was proposed to deposit metastable orthorhombic tin oxide (SnOx) thin films on glass substrates at room temperature. The resultant samples are labeled according ... -
Novel Synthetic Methodology and Total Syntheses of Highly Functionalized Carbazoles and Benzo[c]cinnolines
(Doctoral thesis, 2018-01-19)This dissertation discloses a project encompassing a synthetic strategies and new methods for the synthesis of some functionalized N-heterocyclic compounds. Much attention have been focused to synthesize N-heterocyclic ... -
Novel theoretical tools in jet quenching
(Doctoral thesis, 2023-06-13)Jet quenching er studiet av hvordan egenskapene til en QCD-jet endrer seg når den passerer gjennom varmt nukleært materiale. Dette er relevant for kollisjoner av tunge ioner ved LHC og RHIC, da slike kollisjoner produserer ... -
Novel Tools for Research and Education in Seismology
(Master thesis, 2002)It’s first part describes the noise performances of an inexpensive instrument for seismic data collection; the geophone-based seismograph used in the SEIS-SCHOOL network and now called Cossac Ranger. The analysis of its ... -
Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children
(Peer reviewed; Journal article, 2017-07-19)Pediatric tuberculosis (TB) is challenging to diagnose, confirmed by growth of Mycobacterium tuberculosis at best in 40% of cases. The WHO has assigned high priority to the development of non-sputum diagnostic tools. We ... -
A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway
(Peer reviewed; Journal article, 2013-01-22)Background: Nested PCR is a commonly used technique in diagnosis of malaria owing to its high sensitivity and specificity. However, it is time-consuming, open to considerable risk of contamination and has low cost-efficiency. ... -
A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway
(Peer reviewed; Journal article, 2013-01-22)Background: Nested PCR is a commonly used technique in diagnosis of malaria owing to its high sensitivity and specificity. However, it is time-consuming, open to considerable risk of contamination and has low cost-efficiency. ... -
Novice Difficulties with Language Constructs
(Master thesis, 2013-08-01)Programming is a difficult skill to learn, and programming courses have high dropout rates. In this thesis we study the problems that students have during their first introductory programming course at The University of ... -
De novo missense mutations in the NAA10 gene cause severe non-syndromic developmental delay in males and females
(Peer reviewed; Journal article, 2015)Recent studies revealed the power of whole-exome sequencing to identify mutations in sporadic cases with non-syndromic intellectual disability. We now identified de novo missense variants in NAA10 in two unrelated individuals, ... -
'Now Objects Perceive Me': Art that Interrogates Machine Vision
(Conference lecture, 2016-10-05)This paper analyses three recent works of art that interrogate the relationship between human perception and machine vision: Nadav Assor’s art-documentary Lessons on Leaving Your Body (2014), Muse’s VR music video Revolt ... -
“Now that you are circumcised, you cannot have first sex with your wife”: post circumcision sexual behaviours and beliefs among men in Wakiso district, Uganda
(Peer reviewed; Journal article, 2017)Introduction: Safe male circumcision is an important biomedical intervention in the comprehensive HIV prevention programmes implemented in 14 sub-Saharan African countries with high HIV prevalence. To sustain its partial ... -
Nowcasting av norsk BNP med maskinlæringsalgoritmer
(Master thesis, 2019-09-21)Hvordan det går med økonomien er noe som aktører i finans, bedrifter og det offentlige tjener på å vite så fort som mulig. Blant de viktigste makrotallene er veksten i bruttonasjonalprodukt, som viser verdien av alt som ... -
Nowcasting COVID-19 incidence indicators during the Italian first outbreak
(Journal article; Peer reviewed, 2021)A novel parametric regression model is proposed to fit incidence data typically collected during epidemics. The proposal is motivated by real-time monitoring and short-term forecasting of the main epidemiological indicators ... -
.no®. Forholdet mellom varemerke og overlappande domenenamn ved overdraging og pantsetjing
(Master thesis, 2018-12-10)Avhandlinga tar føre seg samanhengen mellom eit varemerke og eit domenenamn som kan gjere inngrep i varemerkeretten. Problemstillinga er om denne samanhengen kan ha innverknad på avtalar om overdraging og pantsetjing, som ... -
NP-scout: Machine learning approach for the quantification and visualization of the natural product-likeness of small molecules
(Peer reviewed; Journal article, 2019)Natural products (NPs) remain the most prolific resource for the development of small-molecule drugs. Here we report a new machine learning approach that allows the identification of natural products with high accuracy. ... -
NPM1-Mutated Patient-Derived AML Cells Are More Vulnerable to Rac1 Inhibition
(Journal article; Peer reviewed, 2022)The prognosis of acute myeloid leukemia (AML) is poor, especially for the elderly population. Targeted therapy with small molecules may be a potential strategy to overcome chemoresistance and improve survival in AML. We ... -
NR-SAFE: a randomized, double-blind safety trial of high dose nicotinamide riboside in Parkinson’s disease
(Journal article; Peer reviewed, 2023)Nicotinamide adenine dinucleotide (NAD) replenishment therapy using nicotinamide riboside (NR) shows promise for Parkinson’s disease (PD) and other neurodegenerative disorders. However, the optimal dose of NR remains ...