Blar i Bergen Open Research Archive på tittel
Viser treff 11908-11927 av 34099
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Fully-implicit simulation of vertical-equilibrium models with hysteresis and capillary fringe
(Peer reviewed; Journal article, 2016-02)Geological carbon storage represents a new and substantial challenge for the subsurface geosciences. To increase understanding and make good engineering decisions, containment processes and large-scale storage operations ... -
Fun, influence and competence-a mixed methods study of prerequisites for high school students' participation in physical education
(Peer reviewed; Journal article, 2017-03-10)Background: Many adolescents do not reach the recommended levels of physical activity (PA), and students attending vocational studies are less committed to take part in physical education (PE) than other students. The ... -
Function and regulation of phenylalanine and tyrosine hydroxylases from human and Caenorhabditis elegans. With focus in evolutionary aspects and development of new therapies
(Doctoral thesis, 2010-06-11)The family of the aromatic amino acid hydroxylases (AAAH) is well studied in mammals. It includes four members, i.e. phenylalanine hydroxylase (PAH), tyrosine hydroxylase (TH) and the tryptophan hydroxylases (TPH1 and 2). ... -
Function and regulation of Steroid Receptor Coactivator 2. Transcriptional regulation of cellular metabolism
(Doctoral thesis, 2015-12-18)Nuclear hormone receptors (NRs) associate with coregulators to enable complex programs of gene expression. The p160 steroid receptor coactivator 2 (SRC- 2/GRIP1) regulates metabolism and cellular processes in a tissue-specific ... -
A function of profilin in force generation during malaria parasite motility that is independent of actin binding
(Journal article; Peer reviewed, 2020)During transmission of malaria-causing parasites from mosquito to mammal, Plasmodium sporozoites migrate at high speed within the skin to access the bloodstream and infect the liver. This unusual gliding motility is based ... -
Functional activity level reported by an informant is an early predictor of Alzheimer’s disease
(Journal article; Peer reviewed, 2023)Background Loss of autonomy in day-to-day functioning is one of the feared outcomes of Alzheimer’s disease (AD), and relatives may have been worried by subtle behavioral changes in ordinary life situations long before these ... -
Functional analyses of BRCA1 variants of unknown significance found in hereditary breast or ovarian cancer families in Norway: A tool for improved diagnosis
(Doctoral thesis, 2023-03-21)Tumorsuppressorgenet BRCA1 speler mange viktige roller for å hindre tumorutvikling, og endringar i BRCA1-genet er ei av hovudårsakene til arveleg bryst- og eggstokk-kreft (HBOC). I artikkel I vart det laga ei oversikt over ... -
Functional Analyses of Rare Germline Missense BRCA1 Variants Located within and outside Protein Domains with Known Functions
(Journal article; Peer reviewed, 2023-01-19)The BRCA1 protein is implicated in numerous important cellular processes to prevent genomic instability and tumorigenesis, and pathogenic germline variants predispose carriers to hereditary breast and ovarian cancer (HBOC). ... -
Functional analysis and exterior calculus on mixed-dimensional geometries
(Journal article; Peer reviewed, 2020-07-12)We are interested in differential forms on mixed-dimensional geometries, in the sense of a domain containing sets of d-dimensional manifolds, structured hierarchically so that each d-dimensional manifold is contained in ... -
Functional analysis of BRCA1 variants of uncertain significance (VUS)
(Master thesis, 2022-06-01) -
Functional analysis of metagenomes and metatranscriptomes using SEED and KEGG
(Peer reviewed; Journal article, 2011-02-15)Background: Metagenomics is the study of microbial organisms using sequencing applied directly to environmental samples. Technological advances in next-generation sequencing methods are fueling a rapid increase in the ... -
Functional analysis of the nonvisual opsins melanopsin and vertebrate ancient opsin (VA opsin) in Atlantic salmon (Salmo salar)
(Master thesis, 2017-06-15)The role of nonvisual photoreceptors is yet to be elucidated regarding the link to biological function. This study aims to characterise the expression pattern of melanopsin and vertebrate ancient opsin during early ... -
Functional analysis of tilS homologues in Bacteria and Archaea
(Master thesis, 2005-09-09)Out of all of the microorganisms sequenced so far about one third of the genes have unknown function. Several studies have shown that information on evolutionary relationships between unknown genes can aid in the prediction ... -
Functional and animal studies of short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD), a fatty acid beta-oxidation enzyme involved in congenital hyperinsulinism of infancy
(Doctoral thesis, 2021-02-16)Short-chain 3-hydroxyacyl-CoA dehydrogenase (SCHAD) is a mitochondrial enzyme involved in fatty acid β-oxidation and the regulation of β-cell insulin secretion. Its role in insulin secretion became apparent in 2001 when ... -
Functional and Binding H1N1pdm09-Specific Antibody Responses in Occasionally and Repeatedly Vaccinated Healthcare Workers: A Five-Year Study (2009-2014)
(Journal article; Peer reviewed, 2021)Background: In 2009, a novel influenza A/H1N1pdm09 emerged and caused a pandemic. This strain continued to circulate and was therefore included in the seasonal vaccines up to the 2016/2017-season. This provided a unique ... -
Functional and molecular characterisation of a unique double homozygous variant causing ABCA4-related retinopathy
(Master thesis, 2023-06-02) -
Functional and Prognostic Role of MicroRNAs in Cancer Associated Fibroblasts and Stroma in Oral Squamous Cell Carcinoma
(Doctoral thesis, 2023-11-23)Nyere studier har vist at forandringer i bindevevscellene som omgir kreftsvulsten er viktige for utviklingen av munnhulekreft. Kreft stroma kan regulere fenotypen av kreftcellene, og på den måten kan påvirke klinisk forløpet ... -
The functional and structural asymmetries of the superior temporal sulcus
(Peer reviewed; Journal article, 2018-02)The superior temporal sulcus (STS) is an anatomical structure that increasingly interests researchers. This structure appears to receive multisensory input and is involved in several perceptual and cognitive core functions, ... -
Functional annotation of human long noncoding RNAs via molecular phenotyping
(Journal article; Peer reviewed, 2020)Long noncoding RNAs (lncRNAs) constitute the majority of transcripts in the mammalian genomes, and yet, their functions remain largely unknown. As part of the FANTOM6 project, we systematically knocked down the expression ... -
Functional assessment of 3'UTR regulatory elements using the zebrafish (Danio rerio) model system - towards modulating protein levels in Atlantic salmon (Salmo salar) for more sustainable aquaculture
(Master thesis, 2021-11-22)Post-transcriptional regulation is a complex process that encompasses a myriad of different structures and mechanisms. There are several indications that regulatory elements in the 3'UTR play an important role in the ...