Blar i Bergen Open Research Archive på forfatter "Mustafa, Tehmina"
-
MPT64 antigen detection test improves routine diagnosis of extrapulmonary tuberculosis in a low-resource setting: A study from the tertiary care hospital in Zanzibar
Jørstad, Melissa Davidsen; Marijani, Msafiri; Dyrhol-Riise, Anne Ma; Sviland, Lisbeth; Mustafa, Tehmina (Peer reviewed; Journal article, 2018-05-09)Background: Extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. An immunochemistry-based MPT64 antigen detection test (MPT64 test) has reported higher sensitivity in the diagnosis of EPTB compared with conventional ... -
Multiplex Analysis of Pro- or Anti-Inflammatory Serum Cytokines and Chemokines in relation to Gender and Age among Tanzanian Tuberculous Lymphadenitis Patients
Mustafa, Tehmina; Brokstad, Karl Albert; Mfinanga, Sayoki Godfrey M.; Wiker, Harald G (Peer reviewed; Journal article, 2015)Objectives. Tuberculous lymphadenitis is the most common formof extrapulmonary tuberculosis (TB) with a female and paediatric preponderance, postulated to be due to differences in the immune response. The aim of this study ... -
Mycobacterial antigens accumulation in foamy macrophages in murine pulmonary tuberculosis lesions: Association with necrosis and making of cavities
Riaz, Syeda Mariam; Bjune, Gunnar Aksel; Wiker, Harald G; Sviland, Lisbeth; Mustafa, Tehmina (Journal article; Peer reviewed, 2020)Understanding mechanisms of cavitation in tuberculosis (TB) is the missing link that could advance the field towards better control of the infection. Descriptions of human TB suggest that postprimary TB begins as lipid ... -
Mycobacterial antigens in pleural fluid mononuclear cells to diagnose pleural tuberculosis in HIV co-infected patients
Mustafa, Tehmina; Wergeland, Ida; Baba, Kamaldeen; Pathak, Sharad; Hoosen, Anwar A.; Riise, Anne Margarita Dyrhol (Journal article; Peer reviewed, 2020)Background Extra pulmonary manifestation of tuberculosis (TB) accounts for approximately one-half of TB cases in HIV-infected individuals with pleural TB as the second most common location. Even though mycobacteria are ... -
Paediatric Contacts of Adult COVID-19 Patients: Clinical Parameters, Risk Factors, and Outcome
Farooq, Ammara; Sheikh, Taimur Khalil; Syed, Fibhaa; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)Background. There is insufficient data in Pakistan and in South Asia regarding paediatric COVID-19 demographics and related parameters. The main aim of this study was to assess the paediatric population exposed to SARS-CoV-2 ... -
Patient Health Seeking and Diagnostic Delay in Extrapulmonary Tuberculosis: A Hospital Based Study from Central India
Purohit, Manju; Purohit, Rajvi; Mustafa, Tehmina (Peer reviewed; Journal article, 2019)Objective. We aimed to investigate the awareness, health care seeking behavior, and diagnostic delay in extrapulmonary tuberculosis (EPTB) in a resource-constrained setting from Central India. Setting and Method. Questionnaire ... -
A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
Jenum, Synne; Tonby, Kristian; Rueegg, Corina Silvia; Ruhwald, Morten; Kristiansen, Max Per; Bang, Peter; Olsen, Inge Christoffer; Sellæg, Kjersti; Røstad, Kjerstin; Mustafa, Tehmina; Tasken, Kjetil; Kvale, Dag; Mortensen, Rasmus; Riise, Anne Margarita Dyrhol (Journal article; Peer reviewed, 2021)Host-directed-therapy strategies are warranted to fight tuberculosis. Here we assess the safety and immunogenicity of adjunctive vaccination with the H56:IC31 candidate and cyclooxygenase-2-inhibitor treatment (etoricoxib) ... -
Predictors of slow clinical response and extended treatment in patients with extra-pulmonary tuberculosis in Pakistan, A hospital-based prospective study
Ambreen, Atiqa; Tahseen, Sabira; Wali, Ahmad; Jamil, Muhammad; Naqvi, Syed Zeeshan Haider; Safdar, Nauman; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)The optimal duration of treatment in different forms of extrapulmonary tuberculosis (EPTB) is not clearly defined. This study aimed to identify predictors of slow clinical response and extended anti-TB treatment in EPTB ... -
Rapid and Specific Diagnosis of Extrapulmonary Tuberculosis by Immunostaining of Tissues and Aspirates With Anti-MPT64
Purohit, Manju; Sviland, Lisbeth; Wiker, Harald G; Mustafa, Tehmina (Peer reviewed; Journal article, 2017-04)Background: Extrapulmonary tuberculosis (EPTB) constitutes about 15% to 20% of all cases of tuberculosis (TB). The confirmation of EPTB has always been a challenge to laboratory personnel. We aim to evaluate the diagnostic ... -
Role of a Digital Clinical Decision–Support System in General Practitioners’ Management of COPD in Norway
Vijayakumar, Varun Kumar; Mustafa, Tehmina; Nore, Bjarte Kjell; Garatun-Tjeldstø, Kjell Yngvar; Næss, Øystein; Johansen, Odd Erik; Aarli, Bernt Bøgvald (Journal article; Peer reviewed, 2021)Background: The study investigated if a web-based clinical decision–support system (CDSS) tool would improve general practitioners’ (GPs) accuracy of diagnosis and classification of patients with chronic obstructive pulmonary ... -
Successful Outpatient Management of Children at a Secondary Care Hospital in Pakistan in a Dengue Fever Epidemic and Their Clinical Outcomes
Farooq, Ammara; Aurangzeb, Brekhna; Sheikh, Taimur Khalil; Bashir, Huma; Ghuncha, Maryam; Mustafa, Tehmina (Journal article, 2021)Background. There is limited published literature on the feasibility of WHO 2009 guidelines for the management of dengue fever (DF) in Pakistani children. This study aimed to assess the outcome of children with DF who ... -
Viable Mycobacterium tuberculosis in sputum after pulmonary tuberculosis cure
Ambreen, Atiqa; Jamil, Muhammad; Rahman, Mohammad Aqeel Ur; Mustafa, Tehmina (Peer reviewed; Journal article, 2019)Background: Pulmonary tuberculosis (TB) with detectable Mycobacterium tuberculosis in the sputum is a major source of transmission. In resource limited TB endemic settings, cure is declared through sputum smear examination ... -
Xpert MTB/RIF ultra for rapid diagnosis of extrapulmonary tuberculosis in a high‑income low‑tuberculosis prevalence setting
Hoel, Ida Marie; Syre, Heidi; Skarstein, Ingerid; Mustafa, Tehmina (Journal article; Peer reviewed, 2020)The diagnosis of extrapulmonary tuberculosis (EPTB) is often challenging due to paucibacillary nature of the disease. Xpert MTB/RIF Ultra (Ultra) has been developed to improve detection of Mycobacterium tuberculosis complex ...