Blar i Bergen Open Research Archive på forfatter "Mustafa, Tehmina"
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Isoniazid resistance profile and associated levofloxacin and pyrazinamide resistance in rifampicin resistant and sensitive isolates/ from pulmonary and extrapulmonary tuberculosis patients in Pakistan: A laboratory based surveillance study 2015-19
Tahseen, Sabira; Khanzada, Faisal Masood; Rizvi, Alamdar Hussain; Qadir, Mahmood; Ghazal, Aisha; Baloch, Aurangzaib Quadir; Mustafa, Tehmina (Journal article; Peer reviewed, 2020)Background Pakistan is among top five high burden countries for tuberculosis and drug resistant TB. Among rifampicin sensitive new pulmonary TB (PTB), prevalence of isoniazid resistance is 8.3% (95%CI: 7.0–10.7) and ... -
Maternal and paternal tuberculosis is associated with increased asthma and respiratory symptoms in their offspring: a study from Northern Europe
Gyawali, Sanjay; Lopez Cervantes, Juan Pablo; Johannessen, Ane; Gislason, Thorarinn; Holm, Mathias; Janson, Christer; Jögi, Rain; Modig, Lars; Schlünssen, Vivi; Mustafa, Tehmina; Svanes, Cecilie (Journal article; Peer reviewed, 2023)Background: Given the profound impact of tuberculosis (TB) on immunity and given murine studies suggesting that infections may influence immunity across generations, we hypothesize that parental TB might impact health and ... -
A Mouse Model for Latent Tuberculosis
Phyu, S.; Mustafa, Tehmina; Hofstad, T.; Nilsen, Rune; Fosse, R.; Bjune, Gunnar Aksel (Peer reviewed; Journal article, 1998-06)The aim of the study was to establish a reproducible murine model for latent tuberculosis. We propose an operational definition of latent murine tuberculosis as a stable Mycobacterium tuberculosis count in lungs and spleens ... -
A Mouse Model for Slowly Progressive Primary Tuberculosis
Mustafa, Tehmina; Phyu, S.; Nilsen, Rune; Jonsson, Roland; Bjune, Gunnar Aksel (Journal article, 1999-08)The progression from primary Mycobacterium tuberculosis infection to disease is usually slow in humans. The aim of this study was to develop and characterize a mouse model for slowly progressive primary tuberculosis, using ... -
MPT64 antigen detection test improves diagnosis of pediatric extrapulmonary tuberculosis in Mbeya, Tanzania
Grønningen, Erlend; Nanyaro, Marywinnie; Sviland, Lisbet; Ngadaya, Esther; Muller, William; Torres, Lisete; Mfinanga, Sayoki; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)Pediatric extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. A new immunochemistry based MPT64 antigen detection test has shown improved sensitivity compared to current laboratory tests. The aim of this study ... -
MPT64 antigen detection test improves routine diagnosis of extrapulmonary tuberculosis in a low-resource setting: A study from the tertiary care hospital in Zanzibar
Jørstad, Melissa Davidsen; Marijani, Msafiri; Dyrhol-Riise, Anne Ma; Sviland, Lisbeth; Mustafa, Tehmina (Peer reviewed; Journal article, 2018-05-09)Background: Extrapulmonary tuberculosis (EPTB) is a diagnostic challenge. An immunochemistry-based MPT64 antigen detection test (MPT64 test) has reported higher sensitivity in the diagnosis of EPTB compared with conventional ... -
Multiplex Analysis of Pro- or Anti-Inflammatory Serum Cytokines and Chemokines in relation to Gender and Age among Tanzanian Tuberculous Lymphadenitis Patients
Mustafa, Tehmina; Brokstad, Karl Albert; Mfinanga, Sayoki Godfrey M.; Wiker, Harald G (Peer reviewed; Journal article, 2015)Objectives. Tuberculous lymphadenitis is the most common formof extrapulmonary tuberculosis (TB) with a female and paediatric preponderance, postulated to be due to differences in the immune response. The aim of this study ... -
Mycobacterial antigens accumulation in foamy macrophages in murine pulmonary tuberculosis lesions: Association with necrosis and making of cavities
Riaz, Syeda Mariam; Bjune, Gunnar Aksel; Wiker, Harald G; Sviland, Lisbeth; Mustafa, Tehmina (Journal article; Peer reviewed, 2020)Understanding mechanisms of cavitation in tuberculosis (TB) is the missing link that could advance the field towards better control of the infection. Descriptions of human TB suggest that postprimary TB begins as lipid ... -
Mycobacterial antigens in pleural fluid mononuclear cells to diagnose pleural tuberculosis in HIV co-infected patients
Mustafa, Tehmina; Wergeland, Ida; Baba, Kamaldeen; Pathak, Sharad; Hoosen, Anwar A.; Riise, Anne Margarita Dyrhol (Journal article; Peer reviewed, 2020)Background Extra pulmonary manifestation of tuberculosis (TB) accounts for approximately one-half of TB cases in HIV-infected individuals with pleural TB as the second most common location. Even though mycobacteria are ... -
Novel Insights into the Pathogenesis of Human Post-Primary Tuberculosis from Archival Material of the Pre-Antibiotic Era, 1931–1947
Riaz, Syeda Mariam; Hanevik, Kurt; Helgeland, Lars; Sviland, Lisbet; Hunter, Robert L.; Mustafa, Tehmina (Journal article; Peer reviewed, 2023)Objectives: Primary and post-primary tuberculosis (TB) are distinct entities. The aim of this study was to study the histopathology of primary and post-primary TB by using the unique human autopsy material from the ... -
Paediatric Contacts of Adult COVID-19 Patients: Clinical Parameters, Risk Factors, and Outcome
Farooq, Ammara; Sheikh, Taimur Khalil; Syed, Fibhaa; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)Background. There is insufficient data in Pakistan and in South Asia regarding paediatric COVID-19 demographics and related parameters. The main aim of this study was to assess the paediatric population exposed to SARS-CoV-2 ... -
Parental TB associated with offspring asthma and rhinitis
Lopez Cervantes, Juan Pablo; Shigdel, Rajesh; Accordini, S.; Mustafa, Tehmina; Bertelsen, Randi Jacobsen; Makvandi-Nejad, Shokouh; Lerm, M.; Horsnell, W.; Svanes, Cecilie (Journal article; Peer reviewed, 2022)BACKGROUND: Infections in early life are associated with asthma and allergies in one-generation settings; however, the link between parental infection and offspring phenotype is rarely investigated. We aim to study the ... -
Patient Health Seeking and Diagnostic Delay in Extrapulmonary Tuberculosis: A Hospital Based Study from Central India
Purohit, Manju; Purohit, Rajvi; Mustafa, Tehmina (Peer reviewed; Journal article, 2019)Objective. We aimed to investigate the awareness, health care seeking behavior, and diagnostic delay in extrapulmonary tuberculosis (EPTB) in a resource-constrained setting from Central India. Setting and Method. Questionnaire ... -
A Phase I/II randomized trial of H56:IC31 vaccination and adjunctive cyclooxygenase-2-inhibitor treatment in tuberculosis patients
Jenum, Synne; Tonby, Kristian; Rueegg, Corina Silvia; Ruhwald, Morten; Kristiansen, Max Per; Bang, Peter; Olsen, Inge Christoffer; Sellæg, Kjersti; Røstad, Kjerstin; Mustafa, Tehmina; Tasken, Kjetil; Kvale, Dag; Mortensen, Rasmus; Riise, Anne Margarita Dyrhol (Journal article; Peer reviewed, 2021)Host-directed-therapy strategies are warranted to fight tuberculosis. Here we assess the safety and immunogenicity of adjunctive vaccination with the H56:IC31 candidate and cyclooxygenase-2-inhibitor treatment (etoricoxib) ... -
Predictors of slow clinical response and extended treatment in patients with extra-pulmonary tuberculosis in Pakistan, A hospital-based prospective study
Ambreen, Atiqa; Tahseen, Sabira; Wali, Ahmad; Jamil, Muhammad; Naqvi, Syed Zeeshan Haider; Safdar, Nauman; Mustafa, Tehmina (Journal article; Peer reviewed, 2021)The optimal duration of treatment in different forms of extrapulmonary tuberculosis (EPTB) is not clearly defined. This study aimed to identify predictors of slow clinical response and extended anti-TB treatment in EPTB ... -
Previous tuberculosis infection associated with increased frequency of asthma and respiratory symptoms in a Nordic–Baltic multicentre population study
Gyawali, Sanjay; Lopez Cervantes, Juan Pablo; Jögi, Nils Oskar; Mustafa, Tehmina; Johannessen, Ane; Janson, Christer; Holm, Mathias; Modig, Lars; Cramer, Christine; Gislason, Thorarinn; Svanes, Cecilie; Shigdel, Rajesh (Journal article; Peer reviewed, 2023)Background: Tuberculosis (TB) infection induces profound local and systemic, immunological and inflammatory changes that could influence the development of other respiratory diseases; however, the association between TB ... -
Proteomic analysis of peripheral blood mononuclear cells isolated from patients with pulmonary tuberculosis: A pilot study from Zanzibar, Tanzania
Barakat, Ahmed Samy Mohamed Ali; Birkeland, Even; Jørstad, Melissa Davidsen; el Hajj, Magalie; Marijani, Msafiri; Døskeland, Anne Marie Simonne; Mjaavatten, Olav; Berven, Frode Steingrimsen; Mustafa, Tehmina (Journal article; Peer reviewed, 2023)This study aimed at exploring the proteomic profile of PBMCs to predict treatment response in pulmonary tuberculosis (PTB). This was a pilot study conducted among 8 adult patients from Zanzibar, Tanzania with confirmed ... -
Rapid and Specific Diagnosis of Extrapulmonary Tuberculosis by Immunostaining of Tissues and Aspirates With Anti-MPT64
Purohit, Manju; Sviland, Lisbeth; Wiker, Harald G; Mustafa, Tehmina (Peer reviewed; Journal article, 2017-04)Background: Extrapulmonary tuberculosis (EPTB) constitutes about 15% to 20% of all cases of tuberculosis (TB). The confirmation of EPTB has always been a challenge to laboratory personnel. We aim to evaluate the diagnostic ... -
Role of a Digital Clinical Decision–Support System in General Practitioners’ Management of COPD in Norway
Vijayakumar, Varun Kumar; Mustafa, Tehmina; Nore, Bjarte Kjell; Garatun-Tjeldstø, Kjell Yngvar; Næss, Øystein; Johansen, Odd Erik; Aarli, Bernt Bøgvald (Journal article; Peer reviewed, 2021)Background: The study investigated if a web-based clinical decision–support system (CDSS) tool would improve general practitioners’ (GPs) accuracy of diagnosis and classification of patients with chronic obstructive pulmonary ... -
Significance of non-granulomatous cytomorphology on fine needle aspirate in lymphadenitis cases classified as tuberculous by using a composite reference standard
Helle, Ole Magnus Bjørgaas; Kanthali, Mala; Akhtar, Naish; Purohit, Manju; Mustafa, Tehmina (Journal article; Peer reviewed, 2023)Background Fine needle aspiration cytology (FNAC) is established as a first line investigation for tuberculous lymphadenitis (TBLA). We aimed to describe the various cytomorphologic features of tuberculosis (TB) on FNAC ...