Browsing Bergen Open Research Archive by Title

Now showing items 22934-22953 of 35876

    • A novel bicyclic lactone and other polyphenols from the commercially important vegetable Anthriscus cerefolium 

      Slimestad, Rune; Rathe, Bendik Auran; Aesoy, Reidun; Diaz, Andrea Estefania Carpinteyro; Herfindal, Lars; Fossen, Torgils (Journal article; Peer reviewed, 2022)
      Garden chervil, Anthriscus cerefolium (L.) Hoffm. is an important herb commonly applied in Norwegian large-scale commercial kitchens. This species is a highly enriched source of phenolics, containing 1260 mg gallic acid ...

    • Novel biomarkers in multiple sclerosis pathology with a focus on neuroprotection and myelin repair 

      Ahmad, Intakhar (Doctoral thesis, 2024-01-16)
      Multippel sklerose (MS) er en sykdom som fører til skade på nervesystemet, kjennetegnet av definerte områder med vevsskade (lesjoner) i sentralnervesystemet (CNS). Dette resulterer i varig funksjonshemming hos pasienter. ...

    • Novel Calcium-Binding Motif Stabilizes and Increases the Activity of Aspergillus fumigatus Ecto-NADase 

      Ferrario, Eugenio; Kallio, Juha Pekka; Strømland, Øyvind; Ziegler, Mathias (Journal article; Peer reviewed, 2023)
      Nicotinamide adenine dinucleotide (NAD) is an essential molecule in all kingdoms of life, mediating energy metabolism and cellular signaling. Recently, a new class of highly active fungal surface NADases was discovered. ...

    • Novel carbenes, and ruthenium- carbene complexes in ruthenium-based olefin metathesis 

      Thorsen, Petter Aarbø (Master thesis, 2021-11-22)

    • A novel case of impaired C-reactive protein response following open-heart surgery: A case report and review of the literature 

      Vinnes, Erik Wilhelm; Lillemoen, Paul Kjetil Soldal; Persson, Robert; Meyer, Klaus; Haaverstad, Rune; Monsen, Anne-Lise Bjørke (Journal article; Peer reviewed, 2021)
      Background C-reactive protein (CRP) is expected to increase in response to a range of inflammatory stimuli such as infections or extensive tissue trauma. Case report We present a novel case of severely impaired CRP ...

    • A novel CCA attack using decryption errors against LAC 

      Guo, Qian; Johansson, Thomas; Yang, Jing (Peer reviewed; Journal article, 2019)
      Cryptosystems based on Learning with Errors or related problems are central topics in recent cryptographic research. One main witness to this is the NIST Post-Quantum Cryptography Standardization effort. Many submitted ...

    • Novel clearance of muscle proteins by muscle cells 

      Muslimovic, Aida; Friden, Vincent; Starnberg, Karin; Tenstad, Olav; Espedal, Heidi; Vukusic, Kristina; Nyström, Susanne; Wesén, Emelie; Esbjörner, Elin K; Granholm, Kristoffer; Lindahl, Bertil; Hammarsten, Ola (Journal article; Peer reviewed, 2020)
      Blood levels of cardiac troponins (cTn) and myoglobin are analysed when myocardial infarction (MI) is suspected. Here we describe a novel clearance mechanism for muscle proteins by muscle cells. The complete plasma clearance ...

    • A novel collaboration platform: Structuring books as networks 

      Steensen, Ole Eskild (Master thesis, 2018-08-21)
      Ever since Gutenberg introduced the art of printing in Europe in the mid 1400s, the way we consume and author books has remained somewhat static. In spite of several technological advances since that time, the very structure ...

    • A novel concentrated, interdisciplinary group rehabilitation program for patients with chronic obstructive pulmonary disease: Protocol for a nonrandomized clinical intervention study 

      Frisk, Bente; Njøten, Kiri Lovise; Aarli, Bernt Bøgvald; Hystad, Sigurd William; Rykken, Sidsel; Kjosås, Ane; Søfteland, Eirik; Kvale, Gerd (Journal article; Peer reviewed, 2022)
      Background: Pulmonary rehabilitation has been demonstrated to be a highly effective treatment for people with chronic obstructive pulmonary disease (COPD). However, its availability is scarce worldwide, and new and ...

    • A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function 

      Lam, M.; Coppola, S.; Krumbach, Oliver H.F.; Prencipe, Giuseppe; Insalaco, Antonella; Cifaldi, C.; Brigida, I.; Zara, Erika; Scala, Serena; Di Cesare, Silvia; Martinelli, Simone; Di Rocco, Martina; Pascarella, Antonia; Niceta, Marcello; Pantaleoni, Francesca; Ciolfi, Andrea; Netter, Petra; Carisey, Alexandre; Diehl, Michael; Akbarzadeh, Mohammad; Conti, Francesca; Merli, Pietro; Pastore, Anna; Mortera, Stefano Levi; Camerini, Serena; Farina, L; Buchholzer, Marcel; Pannone, L.; Cao, T.; Coban-Akdemir, Zeynep H.; Jhangiani, Shalini N.; Muzny, Donna M.; Gibbs, Richard A.; Basso-Ricci, L.; Chiriaco, M.; Dvorsky, Radovan; Putignani, L.; Carsetti, Rita; Janning, Petra; Stray-Pedersen, Asbjørg; Erichsen, Hans Christian; Horne, AnnaCarin; Bryceson, Yenan; Torralba-Raga, Lamberto; Ramme, Kim; Rosti, Vittorio; Bracaglia, Claudia; Messia, Virginia; Palma, Paolo; Finocchi, Andrea; Lupski, James R. (Peer reviewed; Journal article, 2019)
      Hemophagocytic lymphohistiocytosis (HLH) is characterized by immune dysregulation due to inadequate restraint of overactivated immune cells and is associated with a variable clinical spectrum having overlap with more common ...

    • Novel endoscopic and MRI-based methods for evaluating exocrine pancreatic function in pancreatitis and monogenic forms of diabetes 

      Tjora, Erling (Doctoral thesis, 2013-11-15)
      Background: Monogenic diabetes (Maturity onset diabetes in the young, MODY) are autosomal dominantly inherited diabetes syndromes characterized by diabetes due to beta cell dysfunction, with typical onset of diabetes before ...

    • A Novel Evolutionary Solution Approach for Many-objective Reliability-Redundancy Allocation Problem Based on Objective Prioritization and Constraint Optimization 

      Nath, Rahul (Journal article; Peer reviewed, 2024)
      The reliability redundancy allocation problem (RRAP) has been mostly solved either as a single or as a multi-objective optimization problem. However, this problem also has numerous important constraints which play prominent ...

    • A novel fibrosis index comprising a non-cholesterol sterol accurately predicts HCV-related liver cirrhosis 

      Ydreborg, Magdalena; Lisovskaja, Vera; Lagging, Martin; Christensen, Peer Brehm; Langeland, Nina; Buhl, Mads Rauning; Pedersen, Court; Mørch, Kristine; Wejstål, Rune; Norkrans, Gunnar; Lindh, Magnus; Färkkilä, Martti; Westin, Johan (Peer reviewed; Journal article, 2014-04-03)
      Diagnosis of liver cirrhosis is essential in the management of chronic hepatitis C virus (HCV) infection. Liver biopsy is invasive and thus entails a risk of complications as well as a potential risk of sampling error. ...

    • A novel Geriatric Assessment frailty score predicts two-year mortality after Transcatheter Aortic Valve implantation 

      Skaar, Elisabeth; Eide, Leslie Sofia Pareja; Norekvål, Tone M.; Ranhoff, Anette Hylen; Nordrehaug, Jan Erik; Forman, Daniel E.; Schönenberger, Anders; Hufthammer, Karl Ove; Kuiper, Karel Kier-Jan; Bleie, Øyvind; Haaverstad, Rune; Schaufel, Margrethe Aase; Packer, Erik Jerome Stene; Langørgen, Jørund (Peer reviewed; Journal article, 2018-10-31)
      Aims Established surgical scores have limitations in delineating risk among candidates for transcatheter aortic valve implantation (TAVI). Assessment of frailty might help to estimate the mortality risk and identify patients ...

    • A novel GFP nude rat model to investigate tumor-stroma interactions 

      Yang, Ning; Huang, Bin; Tsinkalovsky, Oleg; Brekkå, Narve; Zhu, Huaiyang; Leiss, Lina; Enger, Per Øyvind; Li, Xingang; Wang, Jian (Peer reviewed; Journal article, 2014-12-21)
      Backgroud: A key strategy for the study of the tumor microenvironment is to implant human tumor cells in an immunodeficient rodent strain ubiquitously expressing a fluorescent marker. Here, a novel nude rat expressing a ...

    • Novel GHB-derived natural products from European mistletoe (Viscum album) 

      Amer, Bashar; Juvik, Ole-Johan; Francis, George William; Fossen, Torgils (Peer reviewed; Journal article, 2013)
      Context: The European white-berry mistletoe [Viscum album L. (Loranthaceae)] is among the oldest known medicinal plants. At present the most important application of mistletoe extracts is in the treatment of cancer. However, ...

    • A novel human NatA N-alpha-terminal acetyltransferase complex: hNaa16p-hNaa10p (hNat2-hArd1) 

      Arnesen, Thomas; Gromyko, Darina; Kagabo, Diane; Betts, Matthew J.; Starheim, Kristian Kobbenes; Varhaug, Jan Erik; Anderson, Dave; Lillehaug, Johan (Peer reviewed; Journal article, 2009-05-29)
      Background: Protein acetylation is among the most common protein modifications. The two major types are post-translational Nε-lysine acetylation catalyzed by KATs (Lysine acetyltransferases, previously named HATs (histone ...

    • Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing 

      Tjensvoll, Kjersti; Lapin, Morten; Gilje, Bjørnar; Garresori, Herish; Oltedal, Satu; Forthun, Rakel Brendsdal; Molven, Anders; Rozenholc, Yves; Nordgård, Oddmund (Journal article; Peer reviewed, 2022)
      Circulating tumor DNA (ctDNA) analysis has emerged as a clinically useful tool for cancer diagnostics and treatment monitoring. However, ctDNA detection is complicated by low DNA concentrations and technical challenges. ...

    • Novel inflammatory biomarkers in thyroid eye disease 

      Ueland, Hans Olav; Ueland, Grethe Åstrøm; Løvås, Kristian; Breivik, Lars Ertesvåg; Thrane, Alexander Stanley; Stokland, Ann-Elin Meling; Rødahl, Eyvind; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2022)
      Purpose: The aim of this study is to identify biochemical inflammatory markers predicting the presence or risk of developing thyroid eye disease (TED) in patients with Graves' disease (GD). Methods: Patients with GD ...

    • Novel Insights into Integrin α11 Expression and Function 

      Alam, Jahedul (Doctoral thesis, 2020-01-31)
      Integrins are a major group of cell surface receptors, which link the extracellular matrix with the cell cytoskeleton. They are heterodimeric proteins consisting of non- covalently bound α- and β-subunits. By regulating ...