Blar i Bergen Open Research Archive på tittel
Viser treff 22973-22992 av 35876
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Novel PCDH10-Wnt-MALAT1 regulatory axis in endometrioid endometrial adenocarcinoma
(Peer reviewed; Journal article, 2019)Key Messages: 1. Protocadherin 10 (PCDH10) is silenced in endometrioid endometrial cancer through promoter hypermethylation. 2. Ectopic expression of PCDH10 inhibits tumour growth and induces cell apoptosis. 3. Transcriptomic ... -
Novel Points of Attack for Targeted Cancer Therapy
(Peer reviewed; Journal article, 2015-01)New molecular insight reveals novel points of attack for targeted cancer therapy. The recent advances in cancer genomics and novel insight into the complex biology of cancer make the promise of personalized, targeted cancer ... -
Novel Points of Attack for Targeted Cancer Therapy
(Peer reviewed; Journal article, 2014-10-30)New molecular insight reveals novel points of attack for targeted cancer therapy. The recent advances in cancer genomics and novel insight into the complex biology of cancer make the promise of personalized, targeted cancer ... -
A novel poly-oxygenated flavone glucoside from aerial parts of the Brazilian plant Neoglaziovia variegata (Bromeliaceae)
(Peer reviewed; Journal article, 2019)Neoglaziovia variegata is endemic to northeastern Brazil. The drought resistant plant produces edible fruits and is used as a fibre plant by rural communities in the Caatinga region where a variety of products are made ... -
Novel preoperative biomarkers and evaluation of altered treatment strategies to improve outcome for endometrial cancer patients
(Doctoral thesis, 2021-10-01)Background: Endometrial cancer is the most common gynecological cancer among women in countries with a high developmental index, and the incidence is expected to rise. Major controversies in the treatment of endometrial ... -
A Novel Prophylaxis Strategy Using Liposomal Vaccine Adjuvant CAF09b Protects against Influenza Virus Disease
(Journal article; Peer reviewed, 2022-02-06)The SARS-CoV-2 pandemic caused a massive health and societal crisis, although the fast development of effective vaccines reduced some of the impact. To prepare for future respiratory virus pandemics, a pan-viral prophylaxis ... -
A novel protist parasite, Salmoxcellia vastator n. gen., n. sp. (Xcelliidae, Perkinsozoa), infecting farmed salmonids in Norway
(Journal article; Peer reviewed, 2021)Background In Norway, x-cell parasites associated with disease in farmed salmonids have been known as a rare phenomenon for two decades. These parasites cause systemic infections in farmed rainbow trout (Oncorhynchus ... -
Novel RAB27A Variant Associated with Late-Onset Hemophagocytic Lymphohistiocytosis Alters Effector Protein Binding
(Journal article; Peer reviewed, 2022)Autosomal recessive mutations in RAB27A are associated with Griscelli syndrome type 2 (GS2), characterized by hypopigmentation and development of early-onset, potentially fatal hemophagocytic lymphohistiocytosis (HLH). We ... -
Novel Reclassification of Adult Diabetes Is Useful to Distinguish Stages of β-Cell Function Linked to the Risk of Vascular Complications: The DOLCE Study From Northern Ukraine
(Journal article; Peer reviewed, 2021)Background: Presently, persons with diabetes are classified as having type 1 (T1D) or type 2 diabetes (T2D) based on clinical diagnosis. However, adult patients exhibit diverse clinical representations and this makes ... -
The novel reconsidered: Emotions and anti-realism in mid-19th-century Scandinavian literature
(Journal article; Peer reviewed, 2021)The aim of the present article is to investigate the novel as remediation of nationalist pedagogy: how was the pedagogical, nationalist project charged with emotions? How did elements from non-realist genres make emotions ... -
A novel splice-affecting HNF1A variant with large population impact on diabetes in Greenland
(Journal article; Peer reviewed, 2023)Background: The genetic disease architecture of Inuit includes a large number of common high-impact variants. Identification of such variants contributes to our understanding of the genetic aetiology of diseases and improves ... -
Novel STAT3 Inhibitors Targeting STAT3 Dimerization by Binding to the STAT3 SH2 Domain
(Journal article; Peer reviewed, 2022)Our drug discovery model has identified two novel STAT3 SH2 domain inhibitors 323–1 and 323–2 (delavatine A stereoisomers) in a series of experiments. In silico computational modeling, drug affinity responsive target ... -
A novel synthesis of tin oxide thin films by the sol-gel process for optoelectronic applications
(Peer reviewed; Journal article, 2015)A novel and simple chemical method based on sol-gel processing was proposed to deposit metastable orthorhombic tin oxide (SnOx) thin films on glass substrates at room temperature. The resultant samples are labeled according ... -
A novel synthesis of tin oxide thin films by the sol-gel process for optoelectronic applications
(Peer reviewed; Journal article, 2015-02-13)A novel and simple chemical method based on sol-gel processing was proposed to deposit metastable orthorhombic tin oxide (SnOx) thin films on glass substrates at room temperature. The resultant samples are labeled according ... -
Novel Synthetic Methodology and Total Syntheses of Highly Functionalized Carbazoles and Benzo[c]cinnolines
(Doctoral thesis, 2018-01-19)This dissertation discloses a project encompassing a synthetic strategies and new methods for the synthesis of some functionalized N-heterocyclic compounds. Much attention have been focused to synthesize N-heterocyclic ... -
Novel theoretical tools in jet quenching
(Doctoral thesis, 2023-06-13)Jet quenching er studiet av hvordan egenskapene til en QCD-jet endrer seg når den passerer gjennom varmt nukleært materiale. Dette er relevant for kollisjoner av tunge ioner ved LHC og RHIC, da slike kollisjoner produserer ... -
Novel Tools for Research and Education in Seismology
(Master thesis, 2002)It’s first part describes the noise performances of an inexpensive instrument for seismic data collection; the geophone-based seismograph used in the SEIS-SCHOOL network and now called Cossac Ranger. The analysis of its ... -
Novel tools to investigate Arc protein molecular function in synaptic plasticity
(Doctoral thesis, 2024-09-11)Synaptisk plastisitet er en korrelasjon for læring og hukommelse i det mammale hjernen, som produserer endringer på et synaptisk nivå i det nevrale nettverket, som kan være av kortvarig eller langvarig art. For langvarige ... -
Novel transcriptional signatures for sputum-independent diagnostics of tuberculosis in children
(Peer reviewed; Journal article, 2017-07-19)Pediatric tuberculosis (TB) is challenging to diagnose, confirmed by growth of Mycobacterium tuberculosis at best in 40% of cases. The WHO has assigned high priority to the development of non-sputum diagnostic tools. We ...