Browsing Bergen Open Research Archive by Title
Now showing items 25473-25492 of 35875
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Polygenic overlap and shared genetic loci between loneliness, severe mental disorders, and cardiovascular disease risk factors suggest shared molecular mechanisms
(Journal article; Peer reviewed, 2021)Clinical and epidemiological evidence suggest that loneliness is associated with severe mental disorders (SMDs) and increases the risk of cardiovascular disease (CVD). However, the mechanisms underlying the relationship ... -
Polygenic overlap between C-reactive protein, plasma lipids, and Alzheimer disease
(Peer reviewed; Journal article, 2015-06)Background—Epidemiological findings suggest a relationship between Alzheimer disease (AD), inflammation, and dyslipidemia, although the nature of this relationship is not well understood. We investigated whether this ... -
Polygenic overlap with body-mass index improves prediction of treatment-resistant schizophrenia
(Journal article; Peer reviewed, 2023)Treatment resistant schizophrenia (TRS) is characterized by repeated treatment failure with antipsychotics. A recent genome-wide association study (GWAS) of TRS showed a polygenic architecture, but no significant loci were ... -
Polygenic risk modeling for prediction of epithelial ovarian cancer risk
(Journal article; Peer reviewed, 2022)Polygenic risk scores (PRS) for epithelial ovarian cancer (EOC) have the potential to improve risk stratification. Joint estimation of Single Nucleotide Polymorphism (SNP) effects in models could improve predictive performance ... -
A polygenic risk score to help discriminate primary adrenal insufficiency of different etiologies
(Journal article; Peer reviewed, 2023)Background Autoimmune Addison's disease (AAD) is the most common cause of primary adrenal insufficiency (PAI). Despite its exceptionally high heritability, tools to estimate disease susceptibility in individual patients ... -
Polygenic scores for schizophrenia and general cognitive ability: associations with six cognitive domains, premorbid intelligence, and cognitive composite score in individuals with a psychotic disorder and in healthy controls
(Journal article; Peer reviewed, 2020-11)Cognitive impairments are considered core features in schizophrenia and other psychotic disorders. Cognitive impairments are, to a lesser degree, also documented in healthy first-degree relatives. Although recent studies ... -
Polygonal faults in the northern North Sea
(Master thesis, 2021-06-01)Polygonal faults have been studied in sedimentary basins at the Norwegian continental shelf and globally as non-tectonic normal faults. The polygonal faults have been recognized for a long time, but no one has described ... -
Polygonalforkastninger - karakteristikk og dannelsesmekanismer. En studie basert på tolking av seismiske data fra Norske-Barentshavsmarginen
(Master thesis, 2014-09-22)Polygonale forkastningssystemer (PFS) er bemerkelsesverdige strukturer som er identifisert i en rekke sedimentære bassenger over hele verden. Polygonalforkastninger er normalforkastninger med små sprang som hovedsakelig ... -
Polyhedra and algorithms for problems bridging notions of connectivity and independence
(Doctoral thesis, 2023-12-21)I denne avhandlinga interesserer vi oss for å finne delgrafer som svarer til utvalgte modeller for begrepene sammenheng og uavhengighet. I korthet betyr dette stabile (også kalt uavhengige) mengder med gitt kardinalitet, ... -
Polyhedral approach to weighted connected matchings in general graphs
(Journal article; Peer reviewed, 2024)A connected matching in a graph G consists of a set of pairwise disjoint edges whose covered vertices induce a connected subgraph of G. While finding a connected matching of maximum cardinality is a well-solved problem, ... -
Polyhedral results and stronger Lagrangean bounds for stable spanning trees
(Journal article; Peer reviewed, 2023)Given a graph G=(V,E) and a set C of unordered pairs of edges regarded as being in conflict, a stable spanning tree in G is a set of edges T inducing a spanning tree in G, such that for each {ei,ej}∈C, at most one of the ... -
Polymastiidae (Demospongiae: Hadromerida) with ornamented exotyles: a review of morphological affinities and description of a new genus and three new species
(Peer reviewed; Journal article, 2016)All polymastiid sponges displaying ornamented exotyles are reviewed and their morphological affinities are reconsidered. The study embraces all known species of Proteleia, Sphaerotylus, Trachyteleia and Tylexocladus as ... -
Polymer Enhanced Foam in Unconsolidated Sand
(Master thesis, 2016-06-01)Foam is an EOR technique that significantly can improve the macroscopic sweep efficiency by lowering the gas mobility. Limited stability of conventional surfactants for foam generation is one of the reasons why foam is not ... -
Polymer flow in porous media: Relevance to Enhanced Oil Recovery
(Peer reviewed; Journal article, 2018-07-10)Polymer flooding is one of the most successful chemical EOR (enhanced oil recovery) methods, and is primarily implemented to accelerate oil production by sweep improvement. However, additional benefits have extended the ... -
Polymer Injectivity : Experimental Studies of Flow in Porous Media for EOR Polymers
(Doctoral thesis, 2021-02-12)Despite the maturity of the polymer flooding process that is applied in enhanced oil recovery (EOR) technologies, the core of the process, which is the flow of the polymer in porous media, is poorly understood. The types ... -
Polymer Injectivity Test Design Using Numerical Simulation
(Journal article; Peer reviewed, 2020-04-03)Polymer flooding is an enhanced oil recovery (EOR) process, which has received increasing interest in the industry. In this process, water-soluble polymers are used to increase injected water viscosity in order to improve ... -
Polymer Injectivity: Investigation of Mechanical Degradation of Enhanced Oil Recovery Polymers Using In-Situ Rheology
(Peer reviewed; Journal article, 2018-12-24)Water soluble polymers have attracted increasing interest in enhanced oil recovery (EOR) processes, especially polymer flooding. Despite the fact that the flow of polymer in porous medium has been a research subject for ... -
The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males
(Journal article; Peer reviewed, 2021)The polymorphism L412F in TLR3 has been associated with several infectious diseases. However, the mechanism underlying this association is still unexplored. Here, we show that the L412F polymorphism in TLR3 is a marker of ... -
Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users
(Peer reviewed; Journal article, 2012-10-27)Introduction: Mammographic density (MD) is one of the strongest known breast cancer risk factors. Estrogen and progestin therapy (EPT) has been associated with increases in MD. Dense breast tissue is characterized by ... -
Polymorphisms in the TP53-MDM2-MDM4-axis in patients with rheumatoid arthritis
(Journal article; Peer reviewed, 2021)Background In addition to being a tumour suppressor, TP53 is a suppressor of inflammation, and dysfunction of this gene has been related to autoimmune diseases. Patients with autoimmunity, such as rheumatoid arthritis ...