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    • N-terminal acetylation of actin by NAA80 is essential for structural integrity of the Golgi apparatus 

      Beigl, Tobias; Hellesvik, Monica; Saraste, Jaakko; Arnesen, Thomas; Aksnes, Henriette (Journal article; Peer reviewed, 2020)
      N-alpha-acetyltransferase 80 (NAA80) was recently demonstrated to acetylate the N-terminus of actin, with NAA80 knockout cells showing actin cytoskeleton-related phenotypes, such as increased formation of membrane protrusions ...

    • N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity 

      Varland, Sylvia; Silva, Rui Duarte; Kjosås, Ine; Faustino, Alexandra; Bogaert, Annelies; Billmann, Maximilian; Boukhatmi, Hadi; Kellen, Barbara; Costanzo, Michael; Drazic, Adrian; Osberg, Camilla; Chan, Katherine; Zhang, Xiang; Tong, Amy Hin Yan; Andreazza, Simonetta; Lee, Juliette J.; Nedyalkova, Lyudmila; Ušaj, Matej; Whitworth, Alexander J.; Andrews, Brenda J.; Moffat, Jason; Myers, Chad L.; Gevaert, Kris; Boone, Charles; Martinho, Rui Gonçalo; Arnesen, Thomas (Journal article; Peer reviewed, 2023)
      Most eukaryotic proteins are N-terminally acetylated, but the functional impact on a global scale has remained obscure. Using genome-wide CRISPR knockout screens in human cells, we reveal a strong genetic dependency between ...

    • N-terminal pro-B-type natriuretic peptide as a prognostic indicator for 30-day mortality following out-of-hospital cardiac arrest: A prospective observational study 

      Aarsetøy, Reidun; Omland, Torbjørn; Røsjø, Helge; Strand, Heidi; Lindner, Thomas Werner; Aarsetøy, Hildegunn; Staines, Harry; Nilsen, Dennis W.T. (Journal article; Peer reviewed, 2020-08-24)
      Background Early risk stratification applying cardiac biomarkers may prove useful in sudden cardiac arrest patients. We investigated the prognostic utility of early-on levels of high sensitivity cardiac troponin-T (hs-cTnT), ...

    • N-terminal pro-B-type natriuretic peptide for prediction of ventricular arrhythmias: Data from the SMASH study 

      Sourour, Nur; Riveland, Egil Aarstad; Næsgaard, Patrycja; Kjekshus, Harald; Larsen, Alf Inge; Omland, Torbjørn; Røsjø, Helge Rørvik; Myhre, Peder Langeland (Journal article; Peer reviewed, 2023)
      Background Elevated N-terminal pro-B-type natriuretic peptide (NT-proBNP) concentrations predict heart failure (HF) and mortality, but whether NT-proBNP predicts ventricular arrhythmias (VA) is not clear. Hypothesis We ...

    • Na+ is shifted from the extracellular to the intracellular compartment and is not inactivated by glycosaminoglycans during high salt conditions in rats 

      Thowsen, Irene Matre; Karlsen, Tine Veronica; Nikpey, Elham; Haslene-Hox, Hanne; Skogstrand, Trude; Randolph, Gwendalyn J.; Zinselmeyer, Bernd H.; Tenstad, Olav; Wiig, Helge (Journal article; Peer reviewed, 2022)
      Recently, studies have emerged suggesting that the skin plays a role as major Na+ reservoir via regulation of the content of glycosaminoglycans and osmotic gradients. We investigated whether there were electrolyte gradients ...

    • NAA10 p.(D10G) and NAA10 p.(L11R) variants hamper formation of the NatA N-terminal acetyltransferase complex 

      Mc Tiernan, Nina; Darbakk, Christine; Ree, Rasmus; Arnesen, Thomas (Journal article; Peer reviewed, 2020)
      The majority of the human proteome is subjected to N-terminal (Nt) acetylation catalysed by N-terminal acetyltransferases (NATs). The NatA complex is composed of two core subunits—the catalytic subunit NAA10 and the ribosomal ...

    • NAA10 p.(N101K) disrupts N-terminal acetyltransferase complex NatA and is associated with developmental delay and hemihypertrophy 

      Mc Tiernan, Nina; Gill, Harinder; Prada, Carlos E.; Pachajoa, Harry; Lores, Juliana; Arnesen, Thomas (Journal article; Peer reviewed, 2020)
      Nearly half of all human proteins are acetylated at their N-termini by the NatA N-terminal acetyltransferase complex. NAA10 is evolutionarily conserved as the catalytic subunit of NatA in complex with NAA15, but may also ...

    • The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson’s disease 

      Brakedal, Brage; Dölle, Christian; Riemer, Frank; Ma, Yilong; Nido, Gonzalo Sanchez; Skeie, Geir Olve; Craven, Alexander R.; Schwarzlmüller, Thomas; Brekke, Njål; Diab, Joseph; Sverkeli, Lars Jansen; Skjeie, Vivian; Varhaug, Kristin Nielsen; Tysnes, Ole-Bjørn; Peng, Shichun; Haugarvoll, Kristoffer; Ziegler, Mathias; Grüner, Renate; Eidelberg, David; Tzoulis, Charalampos (Journal article; Peer reviewed, 2022)
      We conducted a double-blinded phase I clinical trial to establish whether nicotinamide adenine dinucleotide (NAD) replenishment therapy, via oral intake of nicotinamide riboside (NR), is safe, augments cerebral NAD levels, ...

    • The Nag Hammadi Codices as Monastic Books 

      Lundhaug, Hugo; Bull, Christian (Studien und Texte zu Antike und Christentum (STAC);, Book; Peer reviewed, 2023)

    • Named Entity Extraction for Knowledge Graphs: A Literature Overview 

      Al-Moslmi, Tareq Abdo Abdullah; Gallofré Ocaña, Marc; Opdahl, Andreas Lothe; Veres, Csaba (Journal article; Peer reviewed, 2020)
      An enormous amount of digital information is expressed as natural-language (NL) text that is not easily processable by computers. Knowledge Graphs (KG) offer a widely used format for representing information in ...

    • Nano3P-seq: transcriptome-wide analysis of gene expression and tail dynamics using end-capture nanopore cDNA sequencing 

      Begik, Oguzhan; Diensthuber, Gregor; Liu, Huanle; Delgado-Tejedor, Anna; Kontur, Cassandra; Niazi, Adnan Muhammad; Valen, Eivind; Giraldez, Antonio J.; Beaudoin, Jean-Denis; Mattick, John S.; Novoa, Eva Maria (Journal article; Peer reviewed, 2022)
      RNA polyadenylation plays a central role in RNA maturation, fate, and stability. In response to developmental cues, polyA tail lengths can vary, affecting the translation efficiency and stability of mRNAs. Here we develop ...

    • Nanodiamond-treated flax: improving properties of natural fibers 

      Hinzmann, Carsten Peter; Parsons, Drew F.; Fiedler, Johannes; Zalieckas, Justas; Holst, Bodil (Journal article; Peer reviewed, 2023)
      Synthetic fibers are used extensively as reinforcement in composite materials, but many of them face environmental concerns such as high energy consumption during production and complicated decommissioning. Natural fibers ...

    • Nanoplasmonic laser fusion response to Földes and Pokol 

      Csernai, László Pál; Kroo, N; Papp, I; Strottman, Daniel D. (Journal article; Peer reviewed, 2020)
      Földes and Pokol in their letter “Inertial fusion without compression does not work either with or without nanoplasmonics” criticized our works. Here, we refute their argumentation. Our proposed improvement is the combination ...

    • Nanoscale organolanthanum clusters: Nuclearity-directing role of cyclopentadienyl and halogenido ligands 

      Buschmann, Dennis A.; Dietrich, H. Martin; Schneider, David; Birkelbach, Verena M.; Stuhl, Christoph; Törnroos, Karl Wilhelm; Maichle-Mössmer, Cäcilia; Anwander, Reiner (Journal article; Peer reviewed, 2020)
      Tetramethylaluminato/halogenido(X) ligand exchange reactions in half-sandwich complexes [CpRLa(AlMe4)2] are feasible in non-coordinating solvents and provide access to large coordination clusters of the type [CpRLaX2]x. ...

    • Narrative categorization in digital game-based learning: Engagement, motivation & learning 

      Breien, Fredrik Sundt; Wasson, Barbara (Journal article; Peer reviewed, 2021)
      Previous research shows that digital game-based learning (DGBL) can have positive effects on engagement, motivation, and learning and that using narratives may reinforce these effects. A systematic review identified 15 ...

    • Narrative Medical Visualization to Communicate Disease Data 

      Meuschke, Monique; Garrison, Laura Ann; Smit, Noeska Natasja; Bach, Benjamin; Mittentzwei, Sarah; Weiß, Veronika; Bruckner, Stefan; Lawonn, Kai; Preim, Bernhard (Journal article; Peer reviewed, 2022)
      This paper explores narrative techniques combined with medical visualizations to tell data-driven stories about diseases for a general audience. The field of medical illustration uses narrative visualization through ...

    • A Narrative of Oral Care in Palliative Patients 

      Kvalheim, Siri Flagestad; Strand, Gunhild Vesterhus (Journal article; Peer reviewed, 2022)
      Painful oral conditions represent a significant problem for most patients with a serious disease and palliative care needs. The main causes of such conditions may be associated with the underlying disease and its treatment, ...

    • Narrative review of citizen science in environmental epidemiology: Setting the stage for co-created research projects in environmental epidemiology 

      Froeling, Frederique; Gignac, Florence; Hoek, Gerard; Vermeulen, Roel; Nieuwenhuijsen, Mark J.; Ficorilli, Antonella; De Marchi, Bruna; Biggeri, Annibale; Kocman, David; Robinson, Johanna; Grazuleviciene, Regina; Andrusaityte, Sandra; Righi, Valeria; Basagaña, Xavier (Journal article; Peer reviewed, 2021)
      Several citizen science (CS) initiatives have been adopted in environmental science to monitor air and noise pollution, and water quality related to civic concerns. Nevertheless, CS projects in environmental epidemiology ...

    • Narratives of individual capacities: Positive organisational scholarship amongst child welfare workers in Norway 

      Olaniyan, Oyeniyi Samuel; Hetland, Hilde; Karanika-Murray, Maria (Journal article; Peer reviewed, 2022)
      Child welfare services across the world are often criticised for the quality of service and care that they provide. Whilst the validity of some of these criticisms is debatable, critics often neglect to take into account ...

    • Nasal symptoms increase the risk of snoring and snoring increases the risk of nasal symptoms. A longitudinal population study 

      Värendh, Maria; Janson, Christer; Bengtsson, Caroline; Hellgren, Johan; Holm, Mathias; Schlünssen, Vivi; Johannessen, Ane; Franklin, Karl A.; Storaas, Torgeir; Jõgi, Rain; Gislason, Thorarinn; Lindberg, Eva (Journal article; Peer reviewed, 2021)
      Purpose Humans have a preference for nasal breathing during sleep. This 10-year prospective study aimed to determine if nasal symptoms can predict snoring and also if snoring can predict development of nasal symptoms. The ...