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Early human impacts and ecosystem reorganization in southern-central Africa
(Journal article; Peer reviewed, 2021-05-05)Modern Homo sapiens engage in substantial ecosystem modification, but it is difficult to detect the origins or early consequences of these behaviors. Archaeological, geochronological, geomorphological, and paleoenvironmental ... -
Early identification of treatment non-response in first-episode psychosis
(Journal article; Peer reviewed, 2023)Background Approximately one-third of patients with psychotic disorders does not respond to standard antipsychotic treatments. Consensus criteria for treatment resistance (TR) may aid the identification of non-response ... -
Early indicators of disease progression in Fabry disease that may indicate the need for disease-specific treatment initiation: Findings from the opinion-based PREDICT-FD modified Delphi consensus initiative
(Journal article; Peer reviewed, 2020)Objectives The PRoposing Early Disease Indicators for Clinical Tracking in Fabry Disease (PREDICT-FD) initiative aimed to reach consensus among a panel of global experts on early indicators of disease progression that may ... -
Early Induction of Cross-Reactive CD8+ T-Cell Responses in Tonsils After Live-Attenuated Influenza Vaccination in Children
(Journal article; Peer reviewed, 2020)Background Live-attenuated influenza vaccine (LAIV) was licensed for prophylaxis of children 2–17 years old in Europe in 2012 and is administered as a nasal spray. Live-attenuated influenza vaccine induces both mucosal ... -
Early life exposures contributing to accelerated lung function decline in adulthood – a follow-up study of 11,000 adults from the general population
(Journal article; Peer reviewed, 2023)Background We aimed to assess whether exposure to risk factors in early life from conception to puberty continue to contribute to lung function decline later in life by using a pooled cohort comprising approx. 11,000 adults ... -
Early life growth and associations with lung function and bronchial hyperresponsiveness at 11-years of age
(Journal article; Peer reviewed, 2021)Low birthweight and being born small-for-gestational age (SGA) are linked to asthma and impaired lung function. Particularly, poor intrauterine growth followed by rapid catch-up growth during childhood may predispose for ... -
Early life growth is affecting timing of spawning in the semelparous Barents Sea capelin (Mallotus villosus)
(Journal article; Peer reviewed, 2021)Capelin (Mallotus villosus) is a forage fish and a key species in the Barents Sea (BS). The BS capelin are semelparous and hence only spawn once along the north coasts of Norway and Russia before they die. The age at ... -
Early Maladaptive Schemas and Mental Disorders in Adulthood: a Systematic Review and Meta-analysis
(Journal article; Peer reviewed, 2022)Early maladaptive schemas (EMSs) are broad and pervasive themes regarding oneself and one’s relationships with others originating from adverse childhood experiences. Although the concept of EMSs was initially developed for ... -
Early manifestations of genetic risk for neurodevelopmental disorders
(Journal article; Peer reviewed, 2021)Background: Attention deficit/hyperactivity disorder (ADHD), autism spectrum disorder (autism) and schizophrenia are highly heritable neurodevelopmental disorders, affecting the lives of many individuals. It is important ... -
Early Nutritional Interventions with Zinc, Selenium and Vitamin D for Raising Anti-Viral Resistance Against Progressive COVID-19
(Journal article; Peer reviewed, 2020)Objectives: The novel coronavirus infection (COVID-19) conveys a serious threat globally to health and economy because of a lack of vaccines and specific treatments. A common factor for conditions that predispose for serious ... -
Early pilgrimage traditions in South Asia
(Chapter, 2021)This chapter looks at early history of pilgrimage in South Asia. Sacred sites that were believed to offer rewards to those who visited them have been a significant feature of South Asian religious traditions since at least ... -
Early Puberty Is Associated With Higher Academic Achievement in Boys and Girls and Partially Explains Academic Sex Differences
(Journal article; Peer reviewed, 2021-03-29)Purpose On average, boys have lower academic achievement than girls. We investigated whether the timing of puberty is associated with academic achievement, and whether later puberty among boys contributes to the sex ... -
Early radiologic signal of responsiveness to immune checkpoint blockade in microsatellite-stable/mismatch repair-proficient metastatic colorectal cancer
(Journal article; Peer reviewed, 2022)Background: Immune checkpoint blockade (ICB) results in radiologic tumour response dynamics that differ from chemotherapy efficacy measures and require an early signal of clinical utility. Methods: Previously untreated, ... -
Early response evaluation by single cell signaling profiling in acute myeloid leukemia
(Journal article; Peer reviewed, 2023)Aberrant pro-survival signaling is a hallmark of cancer cells, but the response to chemotherapy is poorly understood. In this study, we investigate the initial signaling response to standard induction chemotherapy in a ... -
Early retirement from the labour market among immigrants and natives: A register-based study of Norway
(Journal article; Peer reviewed, 2022)This study investigates early exit from the labour market among natives and immigrants in Norway, and to what extent this be explained by push, pull, or other factors. To answer these questions, we use high-quality Norwegian ... -
Early screening outcomes among non-immigrants and immigrants targeted by BreastScreen Norway, 2010–2019
(Journal article; Peer reviewed, 2022)Aims: This study aimed to analyse results on early screening outcomes, including recall and cancer rates, and histopathological tumour characteristics among non-immigrants and immigrants invited to BreastScreen ... -
Early screening outcomes before, during, and after a randomized controlled trial with digital breast tomosynthesis
(Journal article; Peer reviewed, 2023)Purpose To describe and compare early screening outcomes before, during and after a randomized controlled trial with digital breast tomosynthesis (DBT) including synthetic 2D mammography versus standard digital mammography ... -
Early start of enzyme replacement therapy in pediatric male patients with classical Fabry disease is associated with attenuated disease progression
(Journal article; Peer reviewed, 2022)Background Enzyme replacement therapy (ERT) slows disease progression of Fabry disease (FD), especially when initiated before the onset of irreversible organ damage. However, with the clinically asymptomatic progression ... -
Early surfactant and non-invasive ventilation versus intubation and surfactant: a propensity score-matched national study
(Journal article; Peer reviewed, 2022)Objective: To compare outcome after less invasive surfactant administration (LISA) and primary endotracheal intubation (non-LISA) in infants born before gestational age (GA) 28 weeks. Setting: All neonatal intensive ... -
Early-life course factors and oral health among young Norwegian adults
(Journal article; Peer reviewed, 2021)Objective Using a national sample of young Norwegian adults, we examined whether unpleasant experience with dental care during childhood is associated with tooth loss and oral health–related quality of life in adulthood ...