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Low levels of endogenous anabolic androgenic steroids in females with severe asthma taking corticosteroids
(Journal article; Peer reviewed, 2023)Rationale Patients with severe asthma are dependent upon treatment with high doses of inhaled corticosteroids (ICS) and often also oral corticosteroids (OCS). The extent of endogenous androgenic anabolic steroid (EAAS) ... -
Low Molecular Weight Hydrogel for Wound Healing
(Journal article; Peer reviewed, 2023)Octadecylazanediyl dipropionic acid (C18ADPA) is a zwitterionic amphiphile with a dendritic headgroup. C18ADPA self-assembles to lamellar networks, which encompasses water and forms a low-molecular-weight hydrogel (LMWG). ... -
Low myocardial energetic efficiency is associated with increased mortality in aortic stenosis
(Journal article; Peer reviewed, 2021)Objectives In hypertension, low myocardial energetic efficiency (MEEi) has been documented as an integrated marker of metabolic and left ventricular (LV) myocardial dysfunction. We tested the predictive performance of MEEi ... -
Low Persistence of Inattention Symptoms From Childhood to Adolescence: A Population-Based Study
(Journal article; Peer reviewed, 2023)Objective: To investigate the persistence of dimensional measures of inattention in a population-based, gender-balanced sample of adolescents with parent reports of inattention from childhood and self-reports of inattention ... -
Low risk pregnancies after a cesarean section: Determinants of trial of labor and its failure
(Journal article; Peer reviewed, 2020-01-13)Introduction: In pregnancies after a previous cesarean section (CS), a planned repeat CS delivery has been associated with excess risk of adverse outcome. However, also the alternative, a trial of labor after CS (TOLAC), ... -
Low serum DHEA-S is associated with impaired lung function in women
(Journal article; Peer reviewed, 2020)Background Emerging evidence suggests that androgens and estrogens have a role in respiratory health, but it is largely unknown whether levels of these hormones can affect lung function in adults from the general population. ... -
Low vitamin D, but not tobacco use or high BMI, is associated with long-term disability progression in multiple sclerosis
(Journal article; Peer reviewed, 2021)Background: Low vitamin D levels, tobacco use and high body mass index (BMI) have been linked to adverse disease outcomes in multiple sclerosis (MS), but their influence on long-term disability progression remains unclear. ... -
Low Z-4OHtam concentrations are associated with adverse clinical outcome among early stage premenopausal breast cancer patients treated with adjuvant tamoxifen
(Journal article; Peer reviewed, 2021)Low steady‐state levels of active tamoxifen metabolites have been associated with inferior treatment outcomes. In this retrospective analysis of 406 estrogen receptor‐positive breast cancer (BC) patients receiving adjuvant ... -
Low-energy electron ionization mass spectrometer for efficient detection of low mass species
(Journal article; Peer reviewed, 2021)The design of a high-efficiency mass spectrometer is described, aimed at residual gas detection of low mass species using low-energy electron impact, with particular applications in helium atom microscopy and atomic or ... -
Low-energy probes of no-scale SU(5) super-GUTs
(Journal article; Peer reviewed, 2021)We explore the possible values of the \(\mu \rightarrow e \gamma \) branching ratio, \(\text {BR}(\mu \rightarrow e\gamma )\), and the electron dipole moment (eEDM), \(d_e\), in no-scale SU(5) super-GUT models with the ... -
Low-Intensity Sonoporation-Induced Intracellular Signalling of Pancreatic Cancer Cells, Fibroblasts and Endothelial Cells
(Journal article; Peer reviewed, 2020)The use of ultrasound (US) and microbubbles (MB), usually referred to as sonoporation, has great potential to increase the efficacy of chemotherapy. However, the molecular mechanisms that mediate sonoporation response are ... -
Low-Rank Binary Matrix Approximation in Column-Sum Norm
(Journal article; Peer reviewed, 2020)We consider 𝓁₁-Rank-r Approximation over {GF}(2), where for a binary m× n matrix 𝐀 and a positive integer constant r, one seeks a binary matrix 𝐁 of rank at most r, minimizing the column-sum norm ‖ 𝐀 -𝐁‖₁. We show ... -
The lower airways microbiome and antimicrobial peptides in idiopathic pulmonary fibrosis differ from chronic obstructive pulmonary disease
(Journal article; Peer reviewed, 2022)Background The lower airways microbiome and host immune response in chronic pulmonary diseases are incompletely understood. We aimed to investigate possible microbiome characteristics and key antimicrobial peptides and ... -
The lower airways microbiota and antimicrobial peptides indicate dysbiosis in sarcoidosis
(Journal article; Peer reviewed, 2022-10-19)Background: The role of the pulmonary microbiome in sarcoidosis is unknown. The objectives of this study were the following: (1) examine whether the pulmonary fungal and bacterial microbiota differed in patients with ... -
Lower antibiotic prescription rates in hospitalized COVID-19 patients than influenza patients, a prospective study
(Journal article; Peer reviewed, 2022)Background COVID-19 patients are extensively treated with antibiotics despite few bacterial complications. We aimed to study antibiotic use in hospitalized COVID-19 patients compared to influenza patients in two consecutive ... -
The lower bathyal and abyssal seafloor fauna of eastern Australia
(Journal article; Peer reviewed, 2020)Background Our knowledge of the benthic fauna at lower bathyal to abyssal (LBA, > 2000 m) depths off Eastern Australia was very limited with only a few samples having been collected from these habitats over the last ... -
Lower Cardiac Vagal Activity Predicts Self-Reported Difficulties With Emotion Regulation in Adolescents With ADHD
(Journal article; Peer reviewed, 2020)Objective: To investigate the relation between cardiac vagal activity (CVA), a measure of autonomic nervous system (ANS) flexibility, and self-reported emotion regulation (ER) difficulties in adolescents with attention-d ... -
Lower circulating neuron-specific enolase concentrations in adults and adolescents with severe mental illness
(Journal article; Peer reviewed, 2021)Background: Both neurodegenerative and neurodevelopmental abnormalities have been suggested to be part of the etiopathology of severe mental illness (SMI). Neuron-specific enolase (NSE), mainly located in the neuronal ... -
Lower conversion rate with robotic assisted rectal resections compared with conventional laparoscopy; a national cohort study
(Journal article; Peer reviewed, 2021)Background Conversion from laparoscopic to open access colorectal surgery is associated with a poorer postoperative outcome. The aim of this study was to assess conversion rates and outcomes after standard laparoscopic ... -
Lower education and immigrant background are associated with lower participation in a diabetes education program - Insights from adult patients in the Outcomes & Multi-morbidity In Type 2 diabetes cohort (OMIT)
(Journal article; Peer reviewed, 2023)Objectives Diabetes educational programmes should be offered to patients with type 2 diabetes mellitus (T2DM). We assessed the proportion of diabetes educational program participation among adults with T2DM, and its ...