• Adrenal steroid profiling as a diagnostic tool to differentiate polycystic ovary syndrome from nonclassic congenital adrenal hyperplasia: pinpointing easy screening possibilities and normal cutoff levels using liquid chromatography tandem mass spectrometry 

      Ueland, Grethe Åstrøm; Dahl, Sandra Rinne; Methlie, Paal; Hessen, Saleh; Husebye, Eystein Sverre; Thorsby, Per Medbøe (Journal article; Peer reviewed, 2022)
      Objective To define liquid chromatography tandem mass spectrometry (LC-MS/MS)–based cutoff levels and panels of steroid hormones, to improve diagnosis of nonclassic congenital adrenal hyperplasia (NCCAH) and other partial ...
    • Autoimmune Thyroid Disorders in Autoimmune Addison Disease 

      Stokland, Ann-Elin Meling; Ueland, Grethe Åstrøm; Lima, Kari; Grønning, Kaja; Finnes, Trine Elisabeth; Svendsen, Margrethe; Tomkowicz, Aneta Ewa; Holte, Synnøve Emblem; Sollid, Stina Therese; Debowska, Aleksandra; Singsås, Hallvard; Rensvik, Marthe Landsverk; Lejon, Helle; Sørmo, Dag-Erik; Svare, Anders; Blika, Sigrid; Milova, Petya; Korsgaard, Elin; Husby, Øystein; Breivik, Lars Ertesvåg; Jørgensen, Anders Palmstrøm; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2022)
      Context: Autoimmune thyroid disease is the most common endocrine co-morbidity in autoimmune Addison's disease (AAD), but detailed investigations of prevalence and clinical course is lacking. Objective: Provide comprehensive ...
    • Bedtime Salivary Cortisol as a Screening Test for Cushing Syndrome in Children 

      Ueland, Grethe Åstrøm; Kellmann, Ralf; Davidsen, Melissa Jørstad; Viste, Kristin; Husebye, Eystein Sverre; Almås, Bjørg; Storr, Helen L.; Sagen, Jørn Vegard; Mellgren, Gunnar; Juliusson, Pétur Benedikt; Methlie, Paal (Journal article; Peer reviewed, 2021)
      Background Diagnosing Cushing syndrome (CS) can be challenging. The 24-hour urine free cortisol (UFC) measurement is considered gold standard. This is a laborious test, dependent on correct urine collection. Late-night ...
    • Diabetisk ketoacidose ved bruk av SGLT2-hemmer – en pasientserie 

      Lejlic, Selma; Holmaas, Gunhild; Løvås, Kristian; Ueland, Grethe Åstrøm (Journal article; Peer reviewed, 2023)
      Bakgrunn: Hemmere av natriumglukose-kotransportør 2 (SGLT2-hemmere) benyttes i økende grad ved diabetes type 2. Resultater fra tidligere studier tyder på en økt forekomst av diabetisk ketoacidose ved bruk av disse ...
    • Diagnostic testing of autonomous cortisol secretion in adrenal incidentalomas 

      Ueland, Grethe Åstrøm; Grinde, Thea; Methlie, Paal; Kelp, Oskar; Løvås, Kristian; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2020)
      Objective: Autonomous cortisol secretion (ACS) is a condition with ACTH-independent cortisol overproduction from adrenal incidentalomas (AI) or adrenal hyperplasia. The hypercortisolism is often mild, and most patients ...
    • Fear of Covid 19 during the third wave of infection in Norwegian patients with type 1 diabetes 

      Ueland, Grethe Åstrøm; Ernes, Tony; Madsen, Tone Vonheim; Husebye, Eystein Sverre; Sandberg, Sverre; Løvaas, Karianne Fjeld; Cooper, John (Journal article; Peer reviewed, 2022)
      Objective To study the fear of Covid 19 infection among Norwegian patients with type 1 diabetes. Research design and methods Fear of Covid 19 scale, a validated scale assessing the fear of Covid 19, was sent electronically ...
    • Feminizing adrenal tumor identified by plasma steroid profiling 

      Vogt, Elinor Margrethe Chelsom; Hammerling, Katrin; Sorbye, Halfdan; Heie, Anette; Sulen, André; Ueland, Grethe Åstrøm; Husebye, Eystein Sverre; Methlie, Paal (Journal article; Peer reviewed, 2021)
      Feminizing estrogen-secreting adrenocortical carcinomas (ACCs) are exceedingly rare and carry a poor prognosis. The most common presenting trait is gynecomastia, but enlarged breasts are also a frequent clinical finding ...
    • Intensified follow-up of patients with type 1 diabetes and poor glycaemic control: A multicentre quality improvement collaborative based on data from the Norwegian Diabetes Register for Adults 

      Madsen, Tone Vonheim; Cooper, John Graham; Carlsen, Siri; Loevaas, Karianne; Rekdal, Magne; Igland, Jannicke; Sandberg, Sverre; Ueland, Grethe Åstrøm; Iversen, Marjolein M.; Sølvik, Una Ørvim (Journal article; Peer reviewed, 2023)
      Background Patients with type 1 diabetes mellitus (T1DM) and poor glycaemic control are at high risk of developing microvascular and macrovascular complications. The aim of this study was to determine if a quality improvement ...
    • Molecular Biomarkers in Thyroid Eye Disease: A Literature Review 

      Ueland, Hans Olav; Neset, Mikael Thomassen; Methlie, Paal; Ueland, Grethe Åstrøm; Pakdel, Farzad; Rødahl, Eyvind (Journal article; Peer reviewed, 2023)
      Purpose: Thyroid eye disease (TED) is the most common extrathyroidal manifestation of Graves disease. Patients may be severely affected with eyelid retraction, exophthalmos, diplopia, pain, and threatened vision. ...
    • Novel inflammatory biomarkers in thyroid eye disease 

      Ueland, Hans Olav; Ueland, Grethe Åstrøm; Løvås, Kristian; Breivik, Lars Ertesvåg; Thrane, Alexander Stanley; Stokland, Ann-Elin Meling; Rødahl, Eyvind; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2022)
      Purpose: The aim of this study is to identify biochemical inflammatory markers predicting the presence or risk of developing thyroid eye disease (TED) in patients with Graves' disease (GD). Methods: Patients with GD ...
    • Prevalence, Risk Factors, and Clinical and Biochemical Characteristics of Alemtuzumab-Induced Graves Disease 

      Ueland, Grethe Åstrøm; Ueland, Hans Olav; Stokland, Ann-Elin Meling; Bhan, Alok; Schønberg, Anne; Sollid, Stina Therese; Morgas, Dina Edvarda; Holmøy, Trygve; Lima, Kari; Methlie, Paal; Løvås, Kristian; Torkildsen, Øivind; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2024)
      Objective Atypical Graves disease (GD) is a common complication in multiple sclerosis (MS) patients treated with alemtuzumab. We present epidemiological, clinical, and biochemical characteristics of alemtuzumab-induced ...
    • Substantial changes in inflammatory and cardiovascular biomarkers in patients with autonomous cortisol secretion 

      Ueland, Grethe Åstrøm; Methlie, Paal; Heie, Anette; Stokland, Ann-Elin Meling; Dahle, Anne Lise; Sævik, Åse Bjorvatn; Løvås, Kristian; Husebye, Eystein Sverre (Journal article; Peer reviewed, 2023)
      Objective To map inflammatory biomarkers in patients with autonomous cortisol secretion (ACS) and overt Cushing syndrome (CS). Method Observational study including serum from prospectively included patients with ACS ...
    • Systemic Activation of the Kynurenine Pathway in Graves Disease With and Without Ophthalmopathy 

      Ueland, Hans Olav; Ulvik, Arve; Løvås, Kristian; Wolff, Anette Susanne Bøe; Breivik, Lars Ertesvåg; Stokland, Ann-Elin Meling; Rødahl, Eyvind; Nilsen, Roy Miodini; Husebye, Eystein Sverre; Ueland, Grethe Åstrøm (Journal article; Peer reviewed, 2023)
      Context Graves disease (GD) is one of the most common autoimmune disorders. Recent literature has shown an immune response involving several different inflammatory related proteins in these patients. Objective This ...